(70 nodes) Signaling adaptor activity network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000019778	Uncharacterized protein. (263 aa)
	LOC103129977	Suppressor of cytokine signaling 2. (227 aa)
	ENSPFOP00000023967	PDZ domain-containing protein. (128 aa)
	LOC103147496	Uncharacterized protein. (370 aa)
	sav1	Salvador family WW domain containing protein 1. (396 aa)
	dok3	IRS-type PTB domain-containing protein. (501 aa)
	LOC103137054	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (781 aa)
	gnb4	G protein subunit beta 4. (340 aa)
	ENSPFOP00000000057	DBB domain-containing protein. (602 aa)
	ENSPFOP00000000259	Docking protein 2. (564 aa)
	dok1	Docking protein 1b. (656 aa)
	ENSPFOP00000000889	PH domain-containing protein. (749 aa)
	tradd	Tnfrsf1a-associated via death domain. (292 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
	wdr59	WD repeat domain 59. (958 aa)
	gab2	GRB2-associated binding protein 2. (676 aa)
	ENSPFOP00000004545	Uncharacterized protein. (2084 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (313 aa)
	sh2b3	SH2B adaptor protein 3. (710 aa)
	LOC103146039	Low density lipoprotein receptor adaptor protein 1a. (308 aa)
	LOC103152534	Fibroblast growth factor receptor substrate 2b. (533 aa)
	LOC103155169	Uncharacterized protein. (391 aa)
	LOC103151897	Dual specificity phosphatase 19. (203 aa)
	ENSPFOP00000006593	Mitogen-activated protein kinase 8 interacting protein 3. (1306 aa)
	LOC103129201	Abl-interactor 1b. (491 aa)
	sarm1	Sterile alpha and TIR motif containing 1. (712 aa)
	LOC103145639	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	gab1	GRB2-associated binding protein 1. (756 aa)
	ABI1	Abl-interactor 1a. (494 aa)
	ENSPFOP00000008934	Glutamate receptor interacting protein 2b. (1053 aa)
	LOC103156436	IRS-type PTB domain-containing protein. (512 aa)
	LOC103146452	Guanine nucleotide binding protein (G protein), beta polypeptide 3b. (342 aa)
	ENSPFOP00000010302	SH2B adaptor protein 1. (656 aa)
	ENSPFOP00000010700	Dual specificity phosphatase 19a. (202 aa)
	ENSPFOP00000010893	Si:dkey-17m8.1. (987 aa)
	LOC103145022	Glutamate receptor interacting protein 2a. (1080 aa)
	POC1A	POC1 centriolar protein A. (480 aa)
	LOC103145206	CRK proto-oncogene, adaptor protein. (306 aa)
	SH2B2	SH2B adaptor protein 2. (689 aa)
	ENSPFOP00000011880	Leucine-rich repeat kinase 2. (1882 aa)
	spag9	Sperm associated antigen 9a. (1292 aa)
	ENSPFOP00000012259	Uncharacterized protein. (1267 aa)
	LOC103151235	Signal transducing adaptor family member 2a. (392 aa)
	ENSPFOP00000012744	Glutamate receptor interacting protein 1. (1085 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (2069 aa)
	LOC103145868	SH2 domain-containing protein. (246 aa)
	nck1	Cytoplasmic protein. (394 aa)
	gnb3	Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (340 aa)
	GNB4	Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (340 aa)
	ksr2	Kinase suppressor of ras 2. (958 aa)
	ENSPFOP00000015175	Mitogen-activated protein kinase 8 interacting protein 1a. (579 aa)
	nck2	Cytoplasmic protein. (393 aa)
	LOC103147363	Si:ch211-25d12.7. (253 aa)
	ENSPFOP00000015962	Uncharacterized protein. (295 aa)
	LOC103143142	ABI family, member 3b. (299 aa)
	ENSPFOP00000016741	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1299 aa)
	gnb5	Guanine nucleotide binding protein (G protein), beta 5b. (395 aa)
	ENSPFOP00000017050	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (940 aa)
	mapk8ip2	Mitogen-activated protein kinase 8 interacting protein 2. (1272 aa)
	ENSPFOP00000018047	SH3 and multiple ankyrin repeat domains 3a. (1551 aa)
	ENSPFOP00000018212	SH3 and multiple ankyrin repeat domains 2a. (1922 aa)
	ENSPFOP00000018273	Fibroblast growth factor receptor substrate 3. (553 aa)
	LOC103137809	Fibroblast growth factor receptor substrate 3. (610 aa)
	sh3rf1	SH3 domain containing ring finger 1. (851 aa)
	SPAG9	Sperm associated antigen 9. (1351 aa)
	LOC103133939	Kinase suppressor of ras 1a. (967 aa)
	gab3	PH domain-containing protein. (559 aa)
	LOC103156493	Guanine nucleotide binding protein (G protein), beta 5a. (361 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	ENSPFOP00000000889	ENSPFOP00000008642	ENSPFOP00000000889	Abl-interactor 1a.	PH domain-containing protein.	0.449
ABI1	ENSPFOP00000015962	ENSPFOP00000008642	ENSPFOP00000015962	Abl-interactor 1a.	Uncharacterized protein.	0.614
ABI1	ENSPFOP00000019778	ENSPFOP00000008642	ENSPFOP00000019778	Abl-interactor 1a.	Uncharacterized protein.	0.614
ABI1	LOC103129201	ENSPFOP00000008642	ENSPFOP00000007222	Abl-interactor 1a.	Abl-interactor 1b.	0.899
ABI1	LOC103145206	ENSPFOP00000008642	ENSPFOP00000011517	Abl-interactor 1a.	CRK proto-oncogene, adaptor protein.	0.614
ABI1	crkl	ENSPFOP00000008642	ENSPFOP00000019777	Abl-interactor 1a.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.614
ABI1	gab1	ENSPFOP00000008642	ENSPFOP00000007453	Abl-interactor 1a.	GRB2-associated binding protein 1.	0.449
ABI1	nck1	ENSPFOP00000008642	ENSPFOP00000013873	Abl-interactor 1a.	Cytoplasmic protein.	0.790
ABI1	nck2	ENSPFOP00000008642	ENSPFOP00000015331	Abl-interactor 1a.	Cytoplasmic protein.	0.790
ENSPFOP00000000057	LOC103147363	ENSPFOP00000000057	ENSPFOP00000015851	DBB domain-containing protein.	Si:ch211-25d12.7.	0.509
ENSPFOP00000000259	ENSPFOP00000000889	ENSPFOP00000000259	ENSPFOP00000000889	Docking protein 2.	PH domain-containing protein.	0.531
ENSPFOP00000000259	ENSPFOP00000015962	ENSPFOP00000000259	ENSPFOP00000015962	Docking protein 2.	Uncharacterized protein.	0.674
ENSPFOP00000000259	ENSPFOP00000019778	ENSPFOP00000000259	ENSPFOP00000019778	Docking protein 2.	Uncharacterized protein.	0.674
ENSPFOP00000000259	LOC103145206	ENSPFOP00000000259	ENSPFOP00000011517	Docking protein 2.	CRK proto-oncogene, adaptor protein.	0.674
ENSPFOP00000000259	LOC103147363	ENSPFOP00000000259	ENSPFOP00000015851	Docking protein 2.	Si:ch211-25d12.7.	0.407
ENSPFOP00000000259	crkl	ENSPFOP00000000259	ENSPFOP00000019777	Docking protein 2.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.674
ENSPFOP00000000259	gab1	ENSPFOP00000000259	ENSPFOP00000007453	Docking protein 2.	GRB2-associated binding protein 1.	0.531
ENSPFOP00000000259	nck1	ENSPFOP00000000259	ENSPFOP00000013873	Docking protein 2.	Cytoplasmic protein.	0.489
ENSPFOP00000000259	nck2	ENSPFOP00000000259	ENSPFOP00000015331	Docking protein 2.	Cytoplasmic protein.	0.489
ENSPFOP00000000889	ABI1	ENSPFOP00000000889	ENSPFOP00000008642	PH domain-containing protein.	Abl-interactor 1a.	0.449