STRINGSTRING
ENSPFOP00000026063 ENSPFOP00000026063 lig4 lig4 exosc3 exosc3 rnf168 rnf168 ENSPFOP00000007116 ENSPFOP00000007116 msh2 msh2 UNG UNG LOC103141722 LOC103141722 kiaa1841 kiaa1841 mlh1 mlh1 LOC103140155 LOC103140155 msh6 msh6 ENSPFOP00000026331 ENSPFOP00000026331 ercc1 ercc1 rnf8 rnf8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPFOP00000026063Activation-induced cytidine deaminase. (210 aa)
lig4DNA ligase. (908 aa)
exosc3Exosome component 3. (273 aa)
rnf168Ring finger protein 168. (431 aa)
ENSPFOP00000007116Basic leucine zipper transcription factor, ATF-like. (125 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (937 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (306 aa)
LOC103141722ATPase family AAA domain containing 5a. (1812 aa)
kiaa1841Si:ch211-189k9.2. (708 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (729 aa)
LOC103140155CD40 ligand; Belongs to the tumor necrosis factor family. (237 aa)
msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1379 aa)
ENSPFOP00000026331Uncharacterized protein. (197 aa)
ercc1Excision repair cross-complementation group 1. (356 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (514 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.