(115 nodes) Regulation of synaptic plasticity network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000011488	Zinc finger, ZZ-type with EF hand domain 1. (1873 aa)
	ENSPFOP00000000338	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
	ENSPFOP00000000360	Uncharacterized protein. (1029 aa)
	slc24a2	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (633 aa)
	neto1	Neuropilin (NRP) and tolloid (TLL)-like 1, like. (558 aa)
	ENSPFOP00000001139	Uncharacterized protein. (1189 aa)
	LOC103154709	Neuroplastin b. (390 aa)
	ENSPFOP00000001318	Uncharacterized protein. (194 aa)
	ENSPFOP00000001446	Neurochondrin. (722 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1633 aa)
	LOC103145251	Regulating synaptic membrane exocytosis 3. (324 aa)
	lrrtm2	Leucine rich repeat transmembrane neuronal 2. (546 aa)
	ENSPFOP00000002179	Methyl CpG binding protein 2. (540 aa)
	LOC103154561	Proline-rich transmembrane protein 1. (240 aa)
	ENSPFOP00000002513	NMDA receptor synaptonuclear signaling and neuronal migration factor b. (576 aa)
	gipc1	GIPC PDZ domain containing family, member 1. (335 aa)
	ENSPFOP00000002785	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (891 aa)
	LOC103138590	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1188 aa)
	ENSPFOP00000003012	Uncharacterized protein. (508 aa)
	LOC103147688	Uncharacterized protein. (507 aa)
	LOC103153039	CREB regulated transcription coactivator 1a. (580 aa)
	ENSPFOP00000003455	Si:ch73-330k17.3. (202 aa)
	LOC103144382	Teashirt zinc finger homeobox 3a. (1112 aa)
	ENSPFOP00000004030	Uncharacterized protein. (460 aa)
	ENSPFOP00000004315	Synaptotagmin VIIb. (563 aa)
	ENSPFOP00000004344	Fragile X mental retardation 1. (607 aa)
	ENSPFOP00000004592	Anaphase promoting complex subunit 2; Belongs to the cullin family. (789 aa)
	LOC103139080	YTH N(6)-methyladenosine RNA binding protein 1. (606 aa)
	nf1	Neurofibromin 1b. (2774 aa)
	ENSPFOP00000005447	Teashirt zinc finger homeobox 3b. (1151 aa)
	YTHDF1	YTH N6-methyladenosine RNA binding protein 1. (617 aa)
	LOC103143481	Apolipoprotein Ea. (251 aa)
	ENSPFOP00000005575	Contactin 2. (1039 aa)
	RASGRF1	Ras protein specific guanine nucleotide releasing factor 1. (1266 aa)
	LOC103154846	Activating transcription factor 4a. (424 aa)
	LOC103140931	BAI1-associated protein 2a. (543 aa)
	ENSPFOP00000006545	Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (522 aa)
	NSG1	Neuronal vesicle trafficking associated 1. (185 aa)
	LOC103150940	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1180 aa)
	s100b	S100 calcium binding protein, beta (neural); Belongs to the S-100 family. (94 aa)
	ENSPFOP00000007228	Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (727 aa)
	ENSPFOP00000007287	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (644 aa)
	ENSPFOP00000007731	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a. (963 aa)
	LOC103146510	ELKS/RAB6-interacting/CAST family member 1. (1151 aa)
	LOC103145518	Leucine zipper, putative tumor suppressor 1. (639 aa)
	syap1	Synapse associated protein 1. (365 aa)
	LOC103141587	Apolipoprotein Eb. (265 aa)
	ENSPFOP00000008817	Uncharacterized protein. (1319 aa)
	ENSPFOP00000008851	Uncharacterized protein. (1915 aa)
	SCGN	Secretagogin, EF-hand calcium binding protein. (272 aa)
	LOC103153091	Uncharacterized protein. (343 aa)
	igsf11	Immunoglobulin superfamily member 11. (490 aa)
	ENSPFOP00000010529	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b. (1853 aa)
	LOC103143781	Shisa family member 9b. (379 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1652 aa)
	ENSPFOP00000011353	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (408 aa)
	LOC103142510	Calbindin 2a. (270 aa)
	lgmn	Legumain. (437 aa)
	ENSPFOP00000011940	K(lysine) acetyltransferase 2A. (712 aa)
	ENSPFOP00000012052	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
	ENSPFOP00000012176	Nuclear factor of activated T cells 4. (368 aa)
	kat2a	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (799 aa)
	ncstn	Nicastrin. (701 aa)
	pick1	Protein interacting with prkca 1. (409 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	abhd6	Abhydrolase domain containing 6b. (378 aa)
	ENSPFOP00000013506	Uncharacterized protein. (1569 aa)
	eif4ebp2	Eukaryotic translation initiation factor 4E binding protein 2. (114 aa)
	RELN	Reelin. (3467 aa)
	ENSPFOP00000013739	Protein tyrosine phosphatase non-receptor type 5. (407 aa)
	LOC103142748	Angiotensin-converting enzyme. (640 aa)
	ENSPFOP00000013958	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (454 aa)
	ENSPFOP00000014072	Synaptotagmin XII. (426 aa)
	ENSPFOP00000014315	Neuropilin (NRP) and tolloid (TLL)-like 1. (597 aa)
	ENSPFOP00000014524	Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1677 aa)
	LOC103130040	Synaptogyrin. (237 aa)
	LOC103153877	Abhydrolase domain containing 6. (335 aa)
	ace	Angiotensin-converting enzyme. (1288 aa)
	ENSPFOP00000016127	Uncharacterized protein. (664 aa)
	LOC103149358	BSD domain-containing protein. (341 aa)
	sqstm1	Sequestosome 1. (463 aa)
	shisa8	Shisa family member 8b. (468 aa)
	ENSPFOP00000017524	ELKS/RAB6-interacting/CAST family member 1a. (1105 aa)
	grin2a	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1548 aa)
	LOC103146883	Synaptogyrin 1. (191 aa)
	LOC103136590	Calbindin 2b. (271 aa)
	LOC103146902	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1414 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (1186 aa)
	ENSPFOP00000019165	Regulating synaptic membrane exocytosis 1a. (1501 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1481 aa)
	ENSPFOP00000019801	NMDA receptor synaptonuclear signaling and neuronal migration factor a. (532 aa)
	ENSPFOP00000020513	Leucine rich repeat transmembrane neuronal 1. (522 aa)
	LOC103141262	Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (543 aa)
	LOC103146428	Shisa family member 7. (679 aa)
	ENSPFOP00000023967	PDZ domain-containing protein. (128 aa)
	ENSPFOP00000024367	Uncharacterized protein. (1591 aa)
	LOC103147399	Uncharacterized protein. (434 aa)
	ENSPFOP00000024634	Uncharacterized protein. (128 aa)
	ENSPFOP00000025550	Battenin. (445 aa)
	ENSPFOP00000026162	Serum response factor b. (601 aa)
	ENSPFOP00000026374	Uncharacterized protein. (401 aa)
	ENSPFOP00000026491	Uncharacterized protein. (182 aa)
	ENSPFOP00000027138	Si:ch73-343g19.4. (184 aa)
	LOC103130152	Uncharacterized protein. (278 aa)
	ENSPFOP00000027256	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1039 aa)
	gipc3	GIPC PDZ domain containing family, member 3. (332 aa)
	CRTC1	CREB regulated transcription coactivator 1b. (452 aa)
	LOC103129619	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (983 aa)
	LOC103141308	Synaptotagmin VIIa. (572 aa)
	gipc2	GIPC PDZ domain containing family, member 2. (329 aa)
	syngr1	Synaptogyrin. (233 aa)
	LOC103136663	Shisa family member 7a. (705 aa)
	LOC103147036	BAI1 associated protein 2. (533 aa)
	ENSPFOP00000030391	MADS-box domain-containing protein. (378 aa)
	ENSPFOP00000030811	Shisa family member 9a. (182 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRTC1	LOC103154846	ENSPFOP00000027805	ENSPFOP00000005968	CREB regulated transcription coactivator 1b.	Activating transcription factor 4a.	0.465
EIF2AK4	LOC103154846	ENSPFOP00000010986	ENSPFOP00000005968	Eukaryotic translation initiation factor 2 alpha kinase 4.	Activating transcription factor 4a.	0.585
ENSPFOP00000000338	ENSPFOP00000002785	ENSPFOP00000000338	ENSPFOP00000002785	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.641
ENSPFOP00000000338	LOC103129619	ENSPFOP00000000338	ENSPFOP00000028693	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.881
ENSPFOP00000000360	ENSPFOP00000008817	ENSPFOP00000000360	ENSPFOP00000008817	Uncharacterized protein.	Uncharacterized protein.	0.880
ENSPFOP00000000360	ENSPFOP00000013506	ENSPFOP00000000360	ENSPFOP00000013506	Uncharacterized protein.	Uncharacterized protein.	0.564
ENSPFOP00000000360	ENSPFOP00000019165	ENSPFOP00000000360	ENSPFOP00000019165	Uncharacterized protein.	Regulating synaptic membrane exocytosis 1a.	0.567
ENSPFOP00000000360	LOC103145251	ENSPFOP00000000360	ENSPFOP00000001493	Uncharacterized protein.	Regulating synaptic membrane exocytosis 3.	0.564
ENSPFOP00000000360	RIMS2	ENSPFOP00000000360	ENSPFOP00000019589	Uncharacterized protein.	Regulating synaptic membrane exocytosis 2.	0.880
ENSPFOP00000002179	ENSPFOP00000004344	ENSPFOP00000002179	ENSPFOP00000004344	Methyl CpG binding protein 2.	Fragile X mental retardation 1.	0.597
ENSPFOP00000002179	ENSPFOP00000007731	ENSPFOP00000002179	ENSPFOP00000007731	Methyl CpG binding protein 2.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a.	0.423
ENSPFOP00000002179	ENSPFOP00000010529	ENSPFOP00000002179	ENSPFOP00000010529	Methyl CpG binding protein 2.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b.	0.423
ENSPFOP00000002179	ENSPFOP00000014524	ENSPFOP00000002179	ENSPFOP00000014524	Methyl CpG binding protein 2.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b.	0.472
ENSPFOP00000002179	ENSPFOP00000024367	ENSPFOP00000002179	ENSPFOP00000024367	Methyl CpG binding protein 2.	Uncharacterized protein.	0.423
ENSPFOP00000002179	ENSPFOP00000027256	ENSPFOP00000002179	ENSPFOP00000027256	Methyl CpG binding protein 2.	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.423
ENSPFOP00000002179	GRIN2B	ENSPFOP00000002179	ENSPFOP00000001456	Methyl CpG binding protein 2.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.472
ENSPFOP00000002179	LOC103146902	ENSPFOP00000002179	ENSPFOP00000018450	Methyl CpG binding protein 2.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca.	0.423
ENSPFOP00000002179	grin2a	ENSPFOP00000002179	ENSPFOP00000017687	Methyl CpG binding protein 2.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a.	0.423
ENSPFOP00000002785	ENSPFOP00000000338	ENSPFOP00000002785	ENSPFOP00000000338	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.641
ENSPFOP00000002785	GRIN2B	ENSPFOP00000002785	ENSPFOP00000001456	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.608