(48 nodes) Cardiac muscle cell differentiation network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000030391	MADS-box domain-containing protein. (378 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
	adprhl1	ADP-ribosylhydrolase like 1. (358 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ENSPFOP00000026162	Serum response factor b. (601 aa)
	opa1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1031 aa)
	ENSPFOP00000024185	Uncharacterized protein. (233 aa)
	ENSPFOP00000021548	Uncharacterized protein. (488 aa)
	GREM1	Gremlin. (182 aa)
	ENSPFOP00000020258	Uncharacterized protein. (287 aa)
	ENSPFOP00000020023	Uncharacterized protein. (290 aa)
	ENSPFOP00000020022	Uncharacterized protein. (250 aa)
	ENSPFOP00000019951	T-box transcription factor 5a. (525 aa)
	mef2a	Myocyte enhancer factor 2aa. (527 aa)
	LOC103133914	Lysine (K)-specific demethylase 6B, b. (1594 aa)
	map2k4	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
	LOC103136021	MADS-box domain-containing protein. (463 aa)
	sgcb	Sarcoglycan, beta (dystrophin-associated glycoprotein). (310 aa)
	alpk3	Uncharacterized protein. (1625 aa)
	irx3	Iroquois homeobox 3a. (428 aa)
	ENSPFOP00000016013	Mesoderm posterior ba. (248 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	sirt6	Sirtuin 6. (390 aa)
	LOC103130378	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (642 aa)
	ENSPFOP00000009898	Uncharacterized protein. (655 aa)
	tcap	Titin-cap (telethonin). (179 aa)
	ENSPFOP00000009618	T-box transcription factor 1. (358 aa)
	ENSPFOP00000009563	T-box transcription factor 1. (455 aa)
	hand2	Heart and neural crest derivatives expressed 2. (245 aa)
	LOC103136288	Bone morphogenetic protein 16. (512 aa)
	LOC103142390	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (489 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	ENSPFOP00000007617	FAD-binding FR-type domain-containing protein. (561 aa)
	ENSPFOP00000007219	Uncharacterized protein. (201 aa)
	ENSPFOP00000007079	Blood vessel epicardial substance. (349 aa)
	LOC103148943	Von Willebrand factor A domain containing 5B2. (1391 aa)
	LOC103147840	Uncharacterized protein. (1797 aa)
	LOC103146601	Lysine (K)-specific demethylase 6B, a. (2126 aa)
	ENSPFOP00000003608	TSC complex subunit 1b. (1249 aa)
	nrap	Nebulin-related anchoring protein. (1795 aa)
	bmp2	Bone morphogenetic protein 2b. (419 aa)
	mef2c	Myocyte enhancer factor 2cb. (472 aa)
	ENSPFOP00000002629	Mastermind-like transcriptional coactivator 1. (965 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (422 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	ENSPFOP00000000651	NK2 homeobox 5. (313 aa)
	LOC103131447	Uncharacterized protein. (757 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000000651	ENSPFOP00000007219	ENSPFOP00000000651	ENSPFOP00000007219	NK2 homeobox 5.	Uncharacterized protein.	0.490
ENSPFOP00000000651	ENSPFOP00000009563	ENSPFOP00000000651	ENSPFOP00000009563	NK2 homeobox 5.	T-box transcription factor 1.	0.490
ENSPFOP00000000651	ENSPFOP00000009618	ENSPFOP00000000651	ENSPFOP00000009618	NK2 homeobox 5.	T-box transcription factor 1.	0.490
ENSPFOP00000000651	ENSPFOP00000016013	ENSPFOP00000000651	ENSPFOP00000016013	NK2 homeobox 5.	Mesoderm posterior ba.	0.473
ENSPFOP00000000651	ENSPFOP00000019951	ENSPFOP00000000651	ENSPFOP00000019951	NK2 homeobox 5.	T-box transcription factor 5a.	0.898
ENSPFOP00000000651	ENSPFOP00000026162	ENSPFOP00000000651	ENSPFOP00000026162	NK2 homeobox 5.	Serum response factor b.	0.537
ENSPFOP00000000651	ENSPFOP00000030391	ENSPFOP00000000651	ENSPFOP00000030391	NK2 homeobox 5.	MADS-box domain-containing protein.	0.537
ENSPFOP00000000651	LOC103136021	ENSPFOP00000000651	ENSPFOP00000018300	NK2 homeobox 5.	MADS-box domain-containing protein.	0.829
ENSPFOP00000000651	bmp4	ENSPFOP00000000651	ENSPFOP00000015603	NK2 homeobox 5.	Bone morphogenetic protein 4.	0.478
ENSPFOP00000000651	fgf8	ENSPFOP00000000651	ENSPFOP00000001274	NK2 homeobox 5.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.428
ENSPFOP00000000651	hand2	ENSPFOP00000000651	ENSPFOP00000009486	NK2 homeobox 5.	Heart and neural crest derivatives expressed 2.	0.757
ENSPFOP00000000651	mef2a	ENSPFOP00000000651	ENSPFOP00000019313	NK2 homeobox 5.	Myocyte enhancer factor 2aa.	0.829
ENSPFOP00000000651	mef2c	ENSPFOP00000000651	ENSPFOP00000003129	NK2 homeobox 5.	Myocyte enhancer factor 2cb.	0.859
ENSPFOP00000003608	LOC103133914	ENSPFOP00000003608	ENSPFOP00000019268	TSC complex subunit 1b.	Lysine (K)-specific demethylase 6B, b.	0.825
ENSPFOP00000003608	LOC103146601	ENSPFOP00000003608	ENSPFOP00000003837	TSC complex subunit 1b.	Lysine (K)-specific demethylase 6B, a.	0.825
ENSPFOP00000003608	mtor	ENSPFOP00000003608	ENSPFOP00000008461	TSC complex subunit 1b.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.937
ENSPFOP00000007219	ENSPFOP00000000651	ENSPFOP00000007219	ENSPFOP00000000651	Uncharacterized protein.	NK2 homeobox 5.	0.490
ENSPFOP00000009563	ENSPFOP00000000651	ENSPFOP00000009563	ENSPFOP00000000651	T-box transcription factor 1.	NK2 homeobox 5.	0.490
ENSPFOP00000009618	ENSPFOP00000000651	ENSPFOP00000009618	ENSPFOP00000000651	T-box transcription factor 1.	NK2 homeobox 5.	0.490
ENSPFOP00000016013	ENSPFOP00000000651	ENSPFOP00000016013	ENSPFOP00000000651	Mesoderm posterior ba.	NK2 homeobox 5.	0.473