(97 nodes) Skeletal muscle organ development network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gpcpd1	Glycerophosphocholine phosphodiesterase 1. (673 aa)
	vgll2	Vestigial-like family member 2a. (294 aa)
	LOC103137826	Myozenin 2b. (210 aa)
	myl1	Myosin, light chain 1, alkali; skeletal, fast. (192 aa)
	ENSPFOP00000003607	Uncharacterized protein. (436 aa)
	six1	SIX homeobox 1a. (284 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
	LOC103132550	Kelch-like family member 40b. (612 aa)
	ENSPFOP00000004501	HLF transcription factor, PAR bZIP family member b. (296 aa)
	rb1	Retinoblastoma 1. (913 aa)
	LOC103144233	QKI, KH domain containing, RNA binding a. (342 aa)
	nf1	Neurofibromin 1b. (2774 aa)
	ENSPFOP00000005422	NPHS1 adhesion molecule, nephrin. (1232 aa)
	LOC103142634	Uncharacterized protein. (672 aa)
	ENSPFOP00000005975	R3H domain containing 2. (1063 aa)
	ENSPFOP00000006114	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2452 aa)
	LMOD3	Leiomodin 3. (638 aa)
	ENSPFOP00000006857	Uncharacterized protein. (473 aa)
	ENSPFOP00000007079	Blood vessel epicardial substance. (349 aa)
	LOC103141783	SET and MYND domain containing 1b. (476 aa)
	LOC103152364	Myosin light chain, phosphorylatable, fast skeletal muscle b. (170 aa)
	LOC103146859	MADS-box domain-containing protein. (566 aa)
	LOC103141134	Ankyrin repeat domain 33Aa. (450 aa)
	arpp21	Uncharacterized protein. (640 aa)
	klhl41	Kelch-like family member 41a. (598 aa)
	cemip2	Cell migration inducing hyaluronidase 2. (1389 aa)
	LOC103129995	Dystroglycan 1. (892 aa)
	LOC103136652	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (381 aa)
	LOC103142653	Myogenic factor. (268 aa)
	ENSPFOP00000000019	RNA binding motif protein 24b. (262 aa)
	ENSPFOP00000000021	RNA binding motif protein 24b. (247 aa)
	LOC103129669	Supervillin d. (1480 aa)
	taz	Tafazzin family protein; Belongs to the taffazin family. (262 aa)
	LOC103146108	Kruppel-like factor 5 like. (432 aa)
	LOC103130911	Supervillin d. (1031 aa)
	ENSPFOP00000000769	Dispatched homolog 1 (Drosophila). (925 aa)
	ENSPFOP00000001001	Ankyrin repeat domain 33Ab. (397 aa)
	hoxc8	Homeobox C10a. (396 aa)
	LOC103143420	Myozenin 2a. (264 aa)
	ENSPFOP00000009898	Uncharacterized protein. (655 aa)
	LOC103135272	Ankyrin repeat domain 33ba. (534 aa)
	ENSPFOP00000009950	Bridging integrator 3. (250 aa)
	LOC103130378	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1. (642 aa)
	tcf21	Transcription factor 21. (175 aa)
	ENSPFOP00000011381	Kelch-like family member 41b. (606 aa)
	ripor3	RIPOR family member 3. (994 aa)
	LOC103134743	Kruppel-like factor 5b. (431 aa)
	LOC103138120	Myostatin b. (378 aa)
	meox2	Mesenchyme homeobox 2a. (312 aa)
	kel	Kell metallo-endopeptidase (Kell blood group). (901 aa)
	LOC103135118	RNA binding motif protein 24a. (233 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	ENSPFOP00000013418	Delta/notch-like EGF repeat containing. (770 aa)
	LOC103149376	Myogenic factor. (294 aa)
	mylpf	Myosin light chain, phosphorylatable, fast skeletal muscle a. (170 aa)
	ENSPFOP00000013650	Selenoprotein N. (558 aa)
	LOC103135207	RHO family interacting cell polarization regulator 2. (940 aa)
	ENSPFOP00000014063	HP domain-containing protein. (2199 aa)
	LOC103143955	Supervillin a. (2269 aa)
	LOC103151548	Ankyrin repeat domain 33Bb. (529 aa)
	LOC103136485	SET and MYND domain containing 2a. (435 aa)
	stac3	SH3 and cysteine rich domain 3. (333 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	ENSPFOP00000014522	SPG11 vesicle trafficking associated, spatacsin. (2150 aa)
	ENSPFOP00000014564	E1A binding protein p300 b. (2474 aa)
	ENSPFOP00000014640	Growth differentiation factor 5. (363 aa)
	ENSPFOP00000014836	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (414 aa)
	ENSPFOP00000015212	R3H domain containing 1. (1027 aa)
	ENSPFOP00000015317	Laminin, gamma 3. (1644 aa)
	myo9a	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2632 aa)
	LOC103140457	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	ENSPFOP00000015675	Uncharacterized protein. (201 aa)
	LOC103138383	Kelch-like family member 40a. (613 aa)
	atf3	Activating transcription factor 3. (259 aa)
	ENSPFOP00000017344	Myogenin. (250 aa)
	myf5	Myogenic factor. (240 aa)
	myf6	Myogenic factor 6. (240 aa)
	LOC103142956	Homer scaffold protein 1b. (358 aa)
	unc45b	Unc-45 myosin chaperone B. (930 aa)
	ENSPFOP00000018131	Progesterone immunomodulatory binding factor 1. (516 aa)
	LOC103152156	Popeye domain containing 2. (371 aa)
	hlf	BZIP domain-containing protein. (301 aa)
	ENSPFOP00000018410	Myocyte enhancer factor 2d. (578 aa)
	phox2b	Paired like homeobox 2Bb. (285 aa)
	ENSPFOP00000019034	H2.0-like homeo box 1 (Drosophila). (383 aa)
	lamc1	Laminin, gamma 1. (1620 aa)
	gdf6	Growth differentiation factor 6a. (418 aa)
	ENSPFOP00000020849	Musculin (activated B-cell factor-1). (139 aa)
	ENSPFOP00000022661	Popeye domain containing 3. (289 aa)
	ENSPFOP00000023954	Myostatin b. (358 aa)
	FOXN2	Forkhead box N2b. (410 aa)
	LOC103141828	Peptidase S72 domain-containing protein. (907 aa)
	ENSPFOP00000027390	General transcription factor IIIC, polypeptide 5. (543 aa)
	LOC103150700	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (202 aa)
	ENSPFOP00000028624	Uncharacterized protein. (984 aa)
	MYOZ1	Myozenin 1. (313 aa)
	ENSPFOP00000030727	ANK_REP_REGION domain-containing protein. (422 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000000019	LOC103136652	ENSPFOP00000000019	ENSPFOP00000009377	RNA binding motif protein 24b.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.766
ENSPFOP00000000021	LOC103136652	ENSPFOP00000000021	ENSPFOP00000009377	RNA binding motif protein 24b.	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events.	0.767
ENSPFOP00000000769	LOC103140457	ENSPFOP00000000769	ENSPFOP00000015525	Dispatched homolog 1 (Drosophila).	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.937
ENSPFOP00000000769	smo	ENSPFOP00000000769	ENSPFOP00000003907	Dispatched homolog 1 (Drosophila).	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.556
ENSPFOP00000001001	ENSPFOP00000006114	ENSPFOP00000001001	ENSPFOP00000006114	Ankyrin repeat domain 33Ab.	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.453
ENSPFOP00000001001	ENSPFOP00000009898	ENSPFOP00000001001	ENSPFOP00000009898	Ankyrin repeat domain 33Ab.	Uncharacterized protein.	0.421
ENSPFOP00000001001	cdk5	ENSPFOP00000001001	ENSPFOP00000013235	Ankyrin repeat domain 33Ab.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.465
ENSPFOP00000001001	myo9a	ENSPFOP00000001001	ENSPFOP00000015424	Ankyrin repeat domain 33Ab.	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.453
ENSPFOP00000003607	ENSPFOP00000006857	ENSPFOP00000003607	ENSPFOP00000006857	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSPFOP00000003607	ENSPFOP00000014564	ENSPFOP00000003607	ENSPFOP00000014564	Uncharacterized protein.	E1A binding protein p300 b.	0.424
ENSPFOP00000003607	ENSPFOP00000028624	ENSPFOP00000003607	ENSPFOP00000028624	Uncharacterized protein.	Uncharacterized protein.	0.424
ENSPFOP00000003607	LOC103141783	ENSPFOP00000003607	ENSPFOP00000007458	Uncharacterized protein.	SET and MYND domain containing 1b.	0.692
ENSPFOP00000006114	ENSPFOP00000001001	ENSPFOP00000006114	ENSPFOP00000001001	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Ankyrin repeat domain 33Ab.	0.453
ENSPFOP00000006114	ENSPFOP00000009898	ENSPFOP00000006114	ENSPFOP00000009898	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.422
ENSPFOP00000006114	ENSPFOP00000013418	ENSPFOP00000006114	ENSPFOP00000013418	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Delta/notch-like EGF repeat containing.	0.412
ENSPFOP00000006114	ENSPFOP00000030727	ENSPFOP00000006114	ENSPFOP00000030727	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	ANK_REP_REGION domain-containing protein.	0.453
ENSPFOP00000006114	LOC103130378	ENSPFOP00000006114	ENSPFOP00000010034	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Ankyrin repeat and SOCS box containing 2a, tandem duplicate 1.	0.422
ENSPFOP00000006114	LOC103135272	ENSPFOP00000006114	ENSPFOP00000009915	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Ankyrin repeat domain 33ba.	0.453
ENSPFOP00000006114	LOC103141134	ENSPFOP00000006114	ENSPFOP00000008018	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Ankyrin repeat domain 33Aa.	0.453
ENSPFOP00000006114	LOC103150700	ENSPFOP00000006114	ENSPFOP00000028375	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.608