Your Input: | |||||
usp16 | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (835 aa) | ||||
ENSPFOP00000028108 | Uncharacterized protein. (799 aa) | ||||
ENSPFOP00000028055 | Reverse transcriptase domain-containing protein. (432 aa) | ||||
ENSPFOP00000021397 | Reverse transcriptase domain-containing protein. (784 aa) | ||||
ENSPFOP00000020763 | BRCA1/BRCA2-containing complex, subunit 3. (266 aa) |