(36 nodes) Response to interleukin-1 network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000009709	SCY domain-containing protein. (112 aa)
	LOC103155921	Hyaluronidase. (445 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (876 aa)
	LOC103141111	Nuclear receptor subfamily 1, group D, member 4a. (580 aa)
	LOC103132862	Si:dkey-206d17.12. (370 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (580 aa)
	YTHDC2	YTH domain containing 2. (940 aa)
	ENSPFOP00000004442	Chemokine (C-C motif) ligand 25b. (119 aa)
	LOC103142445	SCY domain-containing protein. (97 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1120 aa)
	LOC103150965	CD40 molecule, TNF receptor superfamily member 5. (313 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	LOC103154418	Interleukin-1. (247 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (658 aa)
	LOC103153072	Nuclear receptor subfamily 1, group d, member 1. (581 aa)
	LOC103151217	C-C motif chemokine. (107 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	LOC103145687	NK3 homeobox 1. (196 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (766 aa)
	acod1	Aconitate decarboxylase 1. (474 aa)
	LOC103135609	Immunoresponsive gene 1, like. (494 aa)
	ENSPFOP00000012266	Immunoresponsive gene 1, like. (495 aa)
	rbmx	RNA binding motif protein X-linked. (383 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (627 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1045 aa)
	tank	TRAF family member-associated NFKB activator. (336 aa)
	LOC103134845	Zmp:0000000936. (524 aa)
	LOC103134846	Uncharacterized protein. (552 aa)
	ENSPFOP00000017743	Ribosomal protein S6 kinase. (805 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (601 aa)
	LOC103133881	Ribosomal protein S6 kinase. (783 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
	akap12	A kinase (PRKA) anchor protein 12b. (1420 aa)
	ENSPFOP00000022883	Uncharacterized protein. (217 aa)
	ENSPFOP00000023625	Peptidase_S8 domain-containing protein. (131 aa)
	irak1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (423 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000004442	ENSPFOP00000009709	ENSPFOP00000004442	ENSPFOP00000009709	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.877
ENSPFOP00000004442	LOC103142445	ENSPFOP00000004442	ENSPFOP00000004598	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.759
ENSPFOP00000004442	LOC103151217	ENSPFOP00000004442	ENSPFOP00000009491	Chemokine (C-C motif) ligand 25b.	C-C motif chemokine.	0.563
ENSPFOP00000009709	ENSPFOP00000004442	ENSPFOP00000009709	ENSPFOP00000004442	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25b.	0.877
ENSPFOP00000009709	LOC103151217	ENSPFOP00000009709	ENSPFOP00000009491	SCY domain-containing protein.	C-C motif chemokine.	0.413
ENSPFOP00000012266	acod1	ENSPFOP00000012266	ENSPFOP00000010842	Immunoresponsive gene 1, like.	Aconitate decarboxylase 1.	0.905
ENSPFOP00000017743	LOC103133881	ENSPFOP00000017743	ENSPFOP00000019031	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.901
ENSPFOP00000022883	LOC103134845	ENSPFOP00000022883	ENSPFOP00000017616	Uncharacterized protein.	Zmp:0000000936.	0.847
ENSPFOP00000022883	LOC103134846	ENSPFOP00000022883	ENSPFOP00000017639	Uncharacterized protein.	Uncharacterized protein.	0.847
ENSPFOP00000022883	LOC103154418	ENSPFOP00000022883	ENSPFOP00000007585	Uncharacterized protein.	Interleukin-1.	0.741
ENSPFOP00000022883	irak1	ENSPFOP00000022883	ENSPFOP00000024246	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.702
ENSPFOP00000022883	map2k7	ENSPFOP00000022883	ENSPFOP00000007380	Uncharacterized protein.	Mitogen-activated protein kinase kinase 7.	0.598
ENSPFOP00000022883	ripk2	ENSPFOP00000022883	ENSPFOP00000003613	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 2.	0.692
ENSPFOP00000022883	traf6	ENSPFOP00000022883	ENSPFOP00000019437	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.989
LOC103132862	rc3h1	ENSPFOP00000002795	ENSPFOP00000005057	Si:dkey-206d17.12.	Ring finger and CCCH-type domains 1b.	0.422
LOC103132862	tank	ENSPFOP00000002795	ENSPFOP00000017547	Si:dkey-206d17.12.	TRAF family member-associated NFKB activator.	0.617
LOC103132862	traf6	ENSPFOP00000002795	ENSPFOP00000019437	Si:dkey-206d17.12.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.408
LOC103133881	ENSPFOP00000017743	ENSPFOP00000019031	ENSPFOP00000017743	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.901
LOC103134845	ENSPFOP00000022883	ENSPFOP00000017616	ENSPFOP00000022883	Zmp:0000000936.	Uncharacterized protein.	0.847
LOC103134845	LOC103134846	ENSPFOP00000017616	ENSPFOP00000017639	Zmp:0000000936.	Uncharacterized protein.	0.844