node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPFOP00000015509 | med1 | ENSPFOP00000015509 | ENSPFOP00000001635 | GATA binding protein 1a. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.563 |
ENSPFOP00000027968 | LHCGR | ENSPFOP00000027968 | ENSPFOP00000015184 | Luteinizing hormone/choriogonadotropin receptor. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.924 |
ENSPFOP00000027968 | slc26a5 | ENSPFOP00000027968 | ENSPFOP00000002847 | Luteinizing hormone/choriogonadotropin receptor. | Solute carrier family 26 member 5. | 0.452 |
LHCGR | ENSPFOP00000027968 | ENSPFOP00000015184 | ENSPFOP00000027968 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Luteinizing hormone/choriogonadotropin receptor. | 0.924 |
LHCGR | slc26a5 | ENSPFOP00000015184 | ENSPFOP00000002847 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Solute carrier family 26 member 5. | 0.452 |
LOC103145124 | slc26a5 | ENSPFOP00000009281 | ENSPFOP00000002847 | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Solute carrier family 26 member 5. | 0.452 |
LOC103147694 | TSHR | ENSPFOP00000001548 | ENSPFOP00000004982 | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.898 |
LOC103147694 | slc26a5 | ENSPFOP00000001548 | ENSPFOP00000002847 | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Solute carrier family 26 member 5. | 0.452 |
TSHR | LOC103147694 | ENSPFOP00000004982 | ENSPFOP00000001548 | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.898 |
TSHR | slc26a5 | ENSPFOP00000004982 | ENSPFOP00000002847 | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Solute carrier family 26 member 5. | 0.452 |
gclc | gclm | ENSPFOP00000009508 | ENSPFOP00000004496 | Glutamate-cysteine ligase, catalytic subunit. | Glutamate-cysteine ligase, modifier subunit. | 0.999 |
gclm | gclc | ENSPFOP00000004496 | ENSPFOP00000009508 | Glutamate-cysteine ligase, modifier subunit. | Glutamate-cysteine ligase, catalytic subunit. | 0.999 |
med1 | ENSPFOP00000015509 | ENSPFOP00000001635 | ENSPFOP00000015509 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | GATA binding protein 1a. | 0.563 |
slc26a5 | ENSPFOP00000027968 | ENSPFOP00000002847 | ENSPFOP00000027968 | Solute carrier family 26 member 5. | Luteinizing hormone/choriogonadotropin receptor. | 0.452 |
slc26a5 | LHCGR | ENSPFOP00000002847 | ENSPFOP00000015184 | Solute carrier family 26 member 5. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.452 |
slc26a5 | LOC103145124 | ENSPFOP00000002847 | ENSPFOP00000009281 | Solute carrier family 26 member 5. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.452 |
slc26a5 | LOC103147694 | ENSPFOP00000002847 | ENSPFOP00000001548 | Solute carrier family 26 member 5. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.452 |
slc26a5 | TSHR | ENSPFOP00000002847 | ENSPFOP00000004982 | Solute carrier family 26 member 5. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.452 |