(13 nodes) Beta-catenin destruction complex network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
	LOC103141624	Axin 2 (conductin, axil). (838 aa)
	cacybp	Calcyclin binding protein. (227 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	LOC103143437	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2468 aa)
	AXIN2	Axin 2. (794 aa)
	LOC103136805	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	ankrd6	Ankyrin repeat domain 6b. (745 aa)
	LOC103130351	APC regulator of WNT signaling pathway. (2033 aa)
	LOC103136433	Uncharacterized protein. (883 aa)
	axin1	Axin 1. (850 aa)
	ENSPFOP00000009363	Ankyrin repeat domain 6a. (637 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	ENSPFOP00000009363	ENSPFOP00000016344	ENSPFOP00000009363	Axin 2.	Ankyrin repeat domain 6a.	0.430
AXIN2	LOC103130351	ENSPFOP00000016344	ENSPFOP00000013359	Axin 2.	APC regulator of WNT signaling pathway.	0.979
AXIN2	LOC103136433	ENSPFOP00000016344	ENSPFOP00000012631	Axin 2.	Uncharacterized protein.	0.902
AXIN2	LOC103136805	ENSPFOP00000016344	ENSPFOP00000016280	Axin 2.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.878
AXIN2	LOC103141624	ENSPFOP00000016344	ENSPFOP00000007069	Axin 2.	Axin 2 (conductin, axil).	0.752
AXIN2	LOC103143437	ENSPFOP00000016344	ENSPFOP00000000142	Axin 2.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.878
AXIN2	ankrd6	ENSPFOP00000016344	ENSPFOP00000014199	Axin 2.	Ankyrin repeat domain 6b.	0.430
AXIN2	apc2	ENSPFOP00000016344	ENSPFOP00000023022	Axin 2.	APC regulator of WNT signaling pathway 2.	0.977
AXIN2	axin1	ENSPFOP00000016344	ENSPFOP00000012187	Axin 2.	Axin 1.	0.902
AXIN2	gsk3b	ENSPFOP00000016344	ENSPFOP00000007509	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.	0.977
ENSPFOP00000009363	AXIN2	ENSPFOP00000009363	ENSPFOP00000016344	Ankyrin repeat domain 6a.	Axin 2.	0.430
ENSPFOP00000009363	LOC103136433	ENSPFOP00000009363	ENSPFOP00000012631	Ankyrin repeat domain 6a.	Uncharacterized protein.	0.430
ENSPFOP00000009363	LOC103141624	ENSPFOP00000009363	ENSPFOP00000007069	Ankyrin repeat domain 6a.	Axin 2 (conductin, axil).	0.430
ENSPFOP00000009363	axin1	ENSPFOP00000009363	ENSPFOP00000012187	Ankyrin repeat domain 6a.	Axin 1.	0.430
LOC103130351	AXIN2	ENSPFOP00000013359	ENSPFOP00000016344	APC regulator of WNT signaling pathway.	Axin 2.	0.979
LOC103130351	LOC103136433	ENSPFOP00000013359	ENSPFOP00000012631	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.982
LOC103130351	LOC103136805	ENSPFOP00000013359	ENSPFOP00000016280	APC regulator of WNT signaling pathway.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.887
LOC103130351	LOC103141624	ENSPFOP00000013359	ENSPFOP00000007069	APC regulator of WNT signaling pathway.	Axin 2 (conductin, axil).	0.982
LOC103130351	LOC103143437	ENSPFOP00000013359	ENSPFOP00000000142	APC regulator of WNT signaling pathway.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.887
LOC103130351	axin1	ENSPFOP00000013359	ENSPFOP00000012187	APC regulator of WNT signaling pathway.	Axin 1.	0.982