(18 nodes) Gamma-carboxyglutamic acid-rich (GLA) domain network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gas6	Uncharacterized protein. (650 aa)
	ENSPFOP00000012768	Coagulation factor IXa. (557 aa)
	LOC103137754	Gla domain-containing protein. (190 aa)
	LOC103138539	Proline rich Gla (G-carboxyglutamic acid) 1. (211 aa)
	ENSPFOP00000017229	Proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane). (222 aa)
	mgp	Gla domain-containing protein. (116 aa)
	LOC103130091	Coagulation factor VII, like. (429 aa)
	LOC103130090	Coagulation factor X. (512 aa)
	LOC103130094	Coagulation factor VII. (450 aa)
	proc	Uncharacterized protein. (485 aa)
	ENSPFOP00000001960	Gla domain-containing protein. (65 aa)
	LOC103141599	Protein Z, vitamin K-dependent plasma glycoprotein a; Belongs to the peptidase S1 family. (419 aa)
	LOC103130178	Uncharacterized protein. (439 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (617 aa)
	LOC103138877	Coagulation factor IXb. (545 aa)
	ENSPFOP00000006407	Protein Z, vitamin K-dependent plasma glycoprotein b; Belongs to the peptidase S1 family. (416 aa)
	LOC103130102	Coagulation factor VIIi. (447 aa)
	pros1	Protein S. (676 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000001960	mgp	ENSPFOP00000001960	ENSPFOP00000021315	Gla domain-containing protein.	Gla domain-containing protein.	0.561
ENSPFOP00000012768	LOC103130090	ENSPFOP00000012768	ENSPFOP00000021497	Coagulation factor IXa.	Coagulation factor X.	0.462
ENSPFOP00000012768	LOC103130094	ENSPFOP00000012768	ENSPFOP00000028410	Coagulation factor IXa.	Coagulation factor VII.	0.624
ENSPFOP00000012768	LOC103130102	ENSPFOP00000012768	ENSPFOP00000006584	Coagulation factor IXa.	Coagulation factor VIIi.	0.473
ENSPFOP00000012768	LOC103130178	ENSPFOP00000012768	ENSPFOP00000005375	Coagulation factor IXa.	Uncharacterized protein.	0.679
ENSPFOP00000012768	f2	ENSPFOP00000012768	ENSPFOP00000005858	Coagulation factor IXa.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.842
LOC103130090	ENSPFOP00000012768	ENSPFOP00000021497	ENSPFOP00000012768	Coagulation factor X.	Coagulation factor IXa.	0.462
LOC103130090	LOC103130094	ENSPFOP00000021497	ENSPFOP00000028410	Coagulation factor X.	Coagulation factor VII.	0.464
LOC103130090	LOC103130178	ENSPFOP00000021497	ENSPFOP00000005375	Coagulation factor X.	Uncharacterized protein.	0.677
LOC103130090	LOC103138877	ENSPFOP00000021497	ENSPFOP00000006072	Coagulation factor X.	Coagulation factor IXb.	0.467
LOC103130090	f2	ENSPFOP00000021497	ENSPFOP00000005858	Coagulation factor X.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.860
LOC103130091	LOC103130178	ENSPFOP00000027789	ENSPFOP00000005375	Coagulation factor VII, like.	Uncharacterized protein.	0.677
LOC103130091	f2	ENSPFOP00000027789	ENSPFOP00000005858	Coagulation factor VII, like.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.842
LOC103130094	ENSPFOP00000012768	ENSPFOP00000028410	ENSPFOP00000012768	Coagulation factor VII.	Coagulation factor IXa.	0.624
LOC103130094	LOC103130090	ENSPFOP00000028410	ENSPFOP00000021497	Coagulation factor VII.	Coagulation factor X.	0.464
LOC103130094	LOC103130102	ENSPFOP00000028410	ENSPFOP00000006584	Coagulation factor VII.	Coagulation factor VIIi.	0.454
LOC103130094	LOC103130178	ENSPFOP00000028410	ENSPFOP00000005375	Coagulation factor VII.	Uncharacterized protein.	0.675
LOC103130094	LOC103138877	ENSPFOP00000028410	ENSPFOP00000006072	Coagulation factor VII.	Coagulation factor IXb.	0.628
LOC103130094	f2	ENSPFOP00000028410	ENSPFOP00000005858	Coagulation factor VII.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.850
LOC103130094	pros1	ENSPFOP00000028410	ENSPFOP00000010256	Coagulation factor VII.	Protein S.	0.414