(12 nodes) ATP-grasp fold network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pcca	Propionyl-CoA carboxylase subunit alpha. (711 aa)
	ttll5	Tubulin tyrosine ligase-like family, member 5. (1258 aa)
	acacb	Acetyl-CoA carboxylase beta. (2418 aa)
	sucla2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
	ENSPFOP00000009049	Ribosomal modification protein rimK-like family member A. (424 aa)
	ENSPFOP00000006411	Uncharacterized protein. (265 aa)
	cps1	Carbamoyl-phosphate synthase 1, mitochondrial. (1508 aa)
	ENSPFOP00000002501	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (994 aa)
	cad	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2234 aa)
	mccc1	Methylcrotonoyl-CoA carboxylase 1 (alpha). (717 aa)
	suclg2	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
	acaca	Acetyl-CoA carboxylase alpha. (2404 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000002501	ENSPFOP00000006411	ENSPFOP00000002501	ENSPFOP00000006411	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Uncharacterized protein.	0.691
ENSPFOP00000002501	acaca	ENSPFOP00000002501	ENSPFOP00000019405	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Acetyl-CoA carboxylase alpha.	0.883
ENSPFOP00000002501	acacb	ENSPFOP00000002501	ENSPFOP00000014338	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Acetyl-CoA carboxylase beta.	0.883
ENSPFOP00000002501	cad	ENSPFOP00000002501	ENSPFOP00000002166	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.934
ENSPFOP00000002501	cps1	ENSPFOP00000002501	ENSPFOP00000003407	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.934
ENSPFOP00000002501	sucla2	ENSPFOP00000002501	ENSPFOP00000010788	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.633
ENSPFOP00000002501	suclg2	ENSPFOP00000002501	ENSPFOP00000021914	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.633
ENSPFOP00000006411	ENSPFOP00000002501	ENSPFOP00000006411	ENSPFOP00000002501	Uncharacterized protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.691
ENSPFOP00000006411	ENSPFOP00000009049	ENSPFOP00000006411	ENSPFOP00000009049	Uncharacterized protein.	Ribosomal modification protein rimK-like family member A.	0.886
ENSPFOP00000006411	acaca	ENSPFOP00000006411	ENSPFOP00000019405	Uncharacterized protein.	Acetyl-CoA carboxylase alpha.	0.795
ENSPFOP00000006411	acacb	ENSPFOP00000006411	ENSPFOP00000014338	Uncharacterized protein.	Acetyl-CoA carboxylase beta.	0.795
ENSPFOP00000006411	mccc1	ENSPFOP00000006411	ENSPFOP00000019293	Uncharacterized protein.	Methylcrotonoyl-CoA carboxylase 1 (alpha).	0.839
ENSPFOP00000006411	pcca	ENSPFOP00000006411	ENSPFOP00000015062	Uncharacterized protein.	Propionyl-CoA carboxylase subunit alpha.	0.839
ENSPFOP00000006411	sucla2	ENSPFOP00000006411	ENSPFOP00000010788	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.664
ENSPFOP00000006411	suclg2	ENSPFOP00000006411	ENSPFOP00000021914	Uncharacterized protein.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.664
ENSPFOP00000009049	ENSPFOP00000006411	ENSPFOP00000009049	ENSPFOP00000006411	Ribosomal modification protein rimK-like family member A.	Uncharacterized protein.	0.886
ENSPFOP00000009049	acaca	ENSPFOP00000009049	ENSPFOP00000019405	Ribosomal modification protein rimK-like family member A.	Acetyl-CoA carboxylase alpha.	0.471
ENSPFOP00000009049	acacb	ENSPFOP00000009049	ENSPFOP00000014338	Ribosomal modification protein rimK-like family member A.	Acetyl-CoA carboxylase beta.	0.471
ENSPFOP00000009049	cad	ENSPFOP00000009049	ENSPFOP00000002166	Ribosomal modification protein rimK-like family member A.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.554
ENSPFOP00000009049	cps1	ENSPFOP00000009049	ENSPFOP00000003407	Ribosomal modification protein rimK-like family member A.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.554