(72 nodes) FERM superfamily, second domain network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000000318	FERM domain-containing protein. (824 aa)
	ENSPFOP00000024493	FERM and PDZ domain containing 3. (1194 aa)
	ENSPFOP00000024266	FERM domain-containing protein. (419 aa)
	jak3	Tyrosine-protein kinase. (1106 aa)
	ENSPFOP00000019987	Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2. (1434 aa)
	ENSPFOP00000019827	Tyrosine-protein kinase. (1128 aa)
	LOC103133954	Moesin a. (579 aa)
	EZR	Ezrin b. (582 aa)
	frmd8	FERM domain containing 8. (467 aa)
	ENSPFOP00000019014	FERM domain containing 3. (608 aa)
	FRMD4A	FERM domain containing 4A. (1061 aa)
	ENSPFOP00000018235	Erythrocyte membrane protein band 4.1a. (689 aa)
	plekhh1	Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1. (1420 aa)
	ENSPFOP00000017362	Myosin VIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2180 aa)
	epb41l4b	Erythrocyte membrane protein band 4.1 like 4B. (772 aa)
	ENSPFOP00000017051	Protein tyrosine phosphatase non-receptor type 3. (875 aa)
	LOC103149891	Talin 2a. (2545 aa)
	FRMPD4	FERM and PDZ domain containing 4. (1662 aa)
	LOC103134342	Uncharacterized protein. (1040 aa)
	frmd6	FERM domain containing 6. (607 aa)
	ENSPFOP00000016294	FERM domain containing 5. (567 aa)
	ENSPFOP00000016291	Uncharacterized protein. (1545 aa)
	ENSPFOP00000016121	Myosin X, like 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2126 aa)
	nf2	Neurofibromin 2a (merlin). (591 aa)
	fermt2	Fermitin family member 2. (695 aa)
	mylip	Myosin regulatory light chain interacting protein a. (481 aa)
	PLEKHH3	Pleckstrin homology, MyTH4 and FERM domain containing H3. (789 aa)
	myo7a	Myosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2180 aa)
	frmd1	FERM domain containing 1. (582 aa)
	EPB41L2	Erythrocyte membrane protein band 4.1 like 2. (1034 aa)
	LOC103139469	Neurofibromin 2b (merlin). (591 aa)
	ENSPFOP00000010050	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1132 aa)
	EPB41L3	Erythrocyte membrane protein band 4.1-like 3a. (813 aa)
	ENSPFOP00000009804	Tyrosine-protein kinase. (1174 aa)
	ENSPFOP00000009702	Fermitin family member 3b. (651 aa)
	LOC103147148	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (942 aa)
	LOC103138634	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (995 aa)
	JAK2	Tyrosine-protein kinase. (1123 aa)
	ENSPFOP00000008555	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2227 aa)
	ENSPFOP00000007653	FERM domain-containing protein. (892 aa)
	LOC103156392	FERM domain-containing protein. (572 aa)
	krit1	KRIT1 ankyrin repeat containing. (739 aa)
	ENSPFOP00000007286	Myosin XVAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2272 aa)
	ENSPFOP00000007239	Ezrin a. (573 aa)
	frmd4b	FERM domain containing 4Bb. (986 aa)
	ENSPFOP00000007026	Protein tyrosine phosphatase non-receptor type 4a. (828 aa)
	ENSPFOP00000006906	Tyrosine-protein kinase. (1155 aa)
	LOC103147326	FERM domain containing 4Ba. (1027 aa)
	ENSPFOP00000006378	Erythrocyte membrane protein band 4.1 like 5. (778 aa)
	LOC103139927	Moesin b. (554 aa)
	ENSPFOP00000006355	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1831 aa)
	RDX	Radixin. (580 aa)
	ptpn13	Protein tyrosine phosphatase non-receptor type 13. (2565 aa)
	ENSPFOP00000005547	FERM domain-containing protein. (445 aa)
	LOC103153231	Talin 1. (2562 aa)
	LOC103152111	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived). (1018 aa)
	ENSPFOP00000004904	FERM domain-containing protein. (584 aa)
	ENSPFOP00000004495	Uncharacterized protein. (2365 aa)
	LOC103134243	Toll-like receptor 7. (1643 aa)
	ENSPFOP00000004226	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1071 aa)
	PTPN14	Protein tyrosine phosphatase non-receptor type 14. (1253 aa)
	ENSPFOP00000003343	Erythrocyte membrane protein band 4.1-like 3b. (948 aa)
	fermt1	Fermitin family member 1. (666 aa)
	ENSPFOP00000003079	Si:ch73-194h10.2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1793 aa)
	ENSPFOP00000002800	Uncharacterized protein. (571 aa)
	ENSPFOP00000001857	FERM and PDZ domain containing 1b. (1576 aa)
	ENSPFOP00000001578	FERM domain-containing protein. (701 aa)
	ENSPFOP00000001075	Myosin XVB. (1736 aa)
	farp2	FERM, RhoGEF and pleckstrin domain protein 2. (1062 aa)
	ENSPFOP00000030551	Uncharacterized protein. (571 aa)
	ENSPFOP00000028518	FERM domain-containing protein. (1311 aa)
	ptpn21	Protein tyrosine phosphatase non-receptor type 21. (1231 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000000318	ENSPFOP00000006378	ENSPFOP00000000318	ENSPFOP00000006378	FERM domain-containing protein.	Erythrocyte membrane protein band 4.1 like 5.	0.555
ENSPFOP00000000318	epb41l4b	ENSPFOP00000000318	ENSPFOP00000017220	FERM domain-containing protein.	Erythrocyte membrane protein band 4.1 like 4B.	0.555
ENSPFOP00000001578	ENSPFOP00000006906	ENSPFOP00000001578	ENSPFOP00000006906	FERM domain-containing protein.	Tyrosine-protein kinase.	0.446
ENSPFOP00000001578	ENSPFOP00000009804	ENSPFOP00000001578	ENSPFOP00000009804	FERM domain-containing protein.	Tyrosine-protein kinase.	0.446
ENSPFOP00000001578	ENSPFOP00000019827	ENSPFOP00000001578	ENSPFOP00000019827	FERM domain-containing protein.	Tyrosine-protein kinase.	0.446
ENSPFOP00000001578	JAK2	ENSPFOP00000001578	ENSPFOP00000008687	FERM domain-containing protein.	Tyrosine-protein kinase.	0.446
ENSPFOP00000001578	jak3	ENSPFOP00000001578	ENSPFOP00000023569	FERM domain-containing protein.	Tyrosine-protein kinase.	0.446
ENSPFOP00000003343	ENSPFOP00000006378	ENSPFOP00000003343	ENSPFOP00000006378	Erythrocyte membrane protein band 4.1-like 3b.	Erythrocyte membrane protein band 4.1 like 5.	0.555
ENSPFOP00000003343	epb41l4b	ENSPFOP00000003343	ENSPFOP00000017220	Erythrocyte membrane protein band 4.1-like 3b.	Erythrocyte membrane protein band 4.1 like 4B.	0.555
ENSPFOP00000004226	ENSPFOP00000006906	ENSPFOP00000004226	ENSPFOP00000006906	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.675
ENSPFOP00000004226	ENSPFOP00000009804	ENSPFOP00000004226	ENSPFOP00000009804	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.675
ENSPFOP00000004226	ENSPFOP00000019827	ENSPFOP00000004226	ENSPFOP00000019827	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.675
ENSPFOP00000004226	JAK2	ENSPFOP00000004226	ENSPFOP00000008687	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.675
ENSPFOP00000004226	LOC103149891	ENSPFOP00000004226	ENSPFOP00000016888	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Talin 2a.	0.670
ENSPFOP00000004226	LOC103153231	ENSPFOP00000004226	ENSPFOP00000005308	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Talin 1.	0.739
ENSPFOP00000004226	jak3	ENSPFOP00000004226	ENSPFOP00000023569	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.675
ENSPFOP00000004495	ENSPFOP00000005547	ENSPFOP00000004495	ENSPFOP00000005547	Uncharacterized protein.	FERM domain-containing protein.	0.475
ENSPFOP00000004495	frmd1	ENSPFOP00000004495	ENSPFOP00000012997	Uncharacterized protein.	FERM domain containing 1.	0.475
ENSPFOP00000004495	frmd6	ENSPFOP00000004495	ENSPFOP00000016322	Uncharacterized protein.	FERM domain containing 6.	0.475
ENSPFOP00000004904	ENSPFOP00000006378	ENSPFOP00000004904	ENSPFOP00000006378	FERM domain-containing protein.	Erythrocyte membrane protein band 4.1 like 5.	0.505