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| | ENSPFOP00000000215 | RAD17 checkpoint clamp loader component. (627 aa) |
| | uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | ENSPFOP00000001341 | RECA_2 domain-containing protein. (301 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (509 aa) |
| | brca2 | BRCA2 DNA repair associated. (3036 aa) |
| | ENSPFOP00000001647 | Uncharacterized protein. (468 aa) |
| | cdca7l | Cell division cycle associated 7b. (401 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | LOC103144613 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | ENSPFOP00000002084 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (346 aa) |
| | ENSPFOP00000002331 | Abraxas 1, BRCA1 A complex subunit. (350 aa) |
| | exo1 | Exonuclease 1. (769 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1822 aa) |
| | sirt7 | Sirtuin 7. (409 aa) |
| | ppp4r2 | Protein phosphatase 4, regulatory subunit 2b. (415 aa) |
| | ENSPFOP00000003275 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (722 aa) |
| | LOC103150116 | Small ubiquitin-related modifier. (96 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | ENSPFOP00000003632 | Nuclear receptor binding SET domain protein 2. (1301 aa) |
| | LOC103132215 | Ubiquitin-like domain-containing protein. (331 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (131 aa) |
| | brca1 | Uncharacterized protein. (1316 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | ENSPFOP00000004987 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (123 aa) |
| | LOC103142380 | RPA_C domain-containing protein. (255 aa) |
| | ENSPFOP00000005090 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1444 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (880 aa) |
| | blm | BLM RecQ like helicase. (1366 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2825 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | LOC103152057 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) |
| | recql4 | RecQ helicase-like 4. (1494 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | ENSPFOP00000006168 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3081 aa) |
| | rnf168 | Ring finger protein 168. (431 aa) |
| | LOC103152896 | Essential meiotic structure-specific endonuclease 1. (519 aa) |
| | LOC103147141 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa) |
| | LOC103144021 | Uncharacterized protein. (439 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (534 aa) |
| | LOC103132650 | Tumor protein p53 binding protein, 1. (1538 aa) |
| | pold1 | DNA polymerase. (1109 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | ENSPFOP00000008634 | Timeless circadian clock. (1126 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (635 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (560 aa) |
| | rnf169 | Ring finger protein 169. (574 aa) |
| | rfc1 | Replication factor C subunit 1. (1166 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (310 aa) |
| | ENSPFOP00000011005 | BRISC and BRCA1 A complex member 2. (331 aa) |
| | pold4 | Si:dkey-28b4.7. (108 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (382 aa) |
| | rad51c | RAD51 paralog C. (357 aa) |
| | rmi2 | RecQ mediated genome instability 2. (146 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (591 aa) |
| | sumo2 | Small ubiquitin-related modifier. (95 aa) |
| | sirt6 | Sirtuin 6. (390 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | cdca7 | Cell division cycle associated 7a. (401 aa) |
| | ENSPFOP00000013426 | Histone H2B; Belongs to the histone H2B family. (122 aa) |
| | ENSPFOP00000013687 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2661 aa) |
| | LOC103148896 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (264 aa) |
| | rpa2 | Replication protein A2. (278 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | ENSPFOP00000014359 | Methionine sulfoxide reductase B1b. (471 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | ENSPFOP00000014388 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | ENSPFOP00000014489 | Uncharacterized protein. (827 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2299 aa) |
| | ENSPFOP00000014766 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (977 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa) |
| | polh | Polymerase (DNA directed), eta. (776 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | ube2i | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | ENSPFOP00000015340 | Uncharacterized protein. (1194 aa) |
| | EME2 | ERCC4 domain-containing protein. (435 aa) |
| | LOC103133374 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa) |
| | ENSPFOP00000015694 | Cyclin A1; Belongs to the cyclin family. (419 aa) |
| | LOC103155113 | Small ubiquitin-related modifier. (94 aa) |
| | nbn | Nibrin. (843 aa) |
| | UBE2N | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (163 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | LOC103129309 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | rhno1 | Si:ch73-352p4.5. (291 aa) |
| | LOC103133711 | KxDL motif containing 1. (185 aa) |
| | LOC103134676 | Uncharacterized protein. (763 aa) |
| | ENSPFOP00000017410 | Uncharacterized protein. (573 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (424 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (301 aa) |
| | LOC103154042 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC103130469 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | ENSPFOP00000018137 | Polymerase (DNA directed) kappa. (592 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa) |
| | ubb | Ubiquitin B. (259 aa) |
| | ENSPFOP00000018931 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (642 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (514 aa) |
| | LOC103144707 | ERCC4 domain-containing protein. (518 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1515 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (462 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | abl1 | Tyrosine-protein kinase. (1117 aa) |
| | LOC103133374-2 | Histone H4. (103 aa) |
| | LOC103133374-3 | Histone H4. (103 aa) |
| | LOC103153205 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | ENSPFOP00000020401 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | ENSPFOP00000020763 | BRCA1/BRCA2-containing complex, subunit 3. (266 aa) |
| | LOC103144613-2 | Histone H2B 1/2. (124 aa) |
| | LOC103144613-3 | Histone H2B 1/2. (124 aa) |
| | LOC103133374-4 | Histone H4. (103 aa) |
| | LOC103154042-2 | Histone H2B 1/2-like. (124 aa) |
| | LOC103154042-3 | Histone H2B 1/2-like. (124 aa) |
| | LOC103133374-5 | Histone H4. (103 aa) |
| | ENSPFOP00000021397 | Reverse transcriptase domain-containing protein. (784 aa) |
| | ENSPFOP00000021872 | RAD9 checkpoint clamp component B. (369 aa) |
| | rad51ap1 | RAD51 associated protein 1. (319 aa) |
| | palb2 | PALB2_WD40 domain-containing protein. (1340 aa) |
| | ENSPFOP00000023184 | Uncharacterized protein. (679 aa) |
| | ENSPFOP00000023229 | Uncharacterized protein. (235 aa) |
| | tdrd3 | Tudor domain containing 3. (786 aa) |
| | ENSPFOP00000025830 | Uncharacterized protein. (2090 aa) |
| | LOC103130469-2 | Histone H2B 1/2-like. (124 aa) |
| | ENSPFOP00000028055 | Reverse transcriptase domain-containing protein. (432 aa) |
| | ENSPFOP00000028108 | Uncharacterized protein. (799 aa) |
| | ENSPFOP00000028950 | Reverse transcriptase domain-containing protein. (609 aa) |
| | ENSPFOP00000029491 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa) |
| | ENSPFOP00000030884 | Small ubiquitin like modifier 3b. (141 aa) |
