STRINGSTRING
ENSPFOP00000021872 ENSPFOP00000021872 ENSPFOP00000022327 ENSPFOP00000022327 ENSPFOP00000023184 ENSPFOP00000023184 hipk3 hipk3 LOC103144355 LOC103144355 tdrd3 tdrd3 prkag1 prkag1 ENSPFOP00000026321 ENSPFOP00000026321 tp53inp1 tp53inp1 ENSPFOP00000030916 ENSPFOP00000030916 ENSPFOP00000000215 ENSPFOP00000000215 nuak2 nuak2 LOC103130849 LOC103130849 LOC103139502 LOC103139502 ENSPFOP00000000831 ENSPFOP00000000831 LOC103155213 LOC103155213 ENSPFOP00000001063 ENSPFOP00000001063 uba52 uba52 LOC103152767 LOC103152767 dyrk2 dyrk2 cdca7l cdca7l LOC103154558 LOC103154558 supt16h supt16h exo1 exo1 ankrd12 ankrd12 AURKB AURKB ENSPFOP00000002713 ENSPFOP00000002713 ENSPFOP00000002806 ENSPFOP00000002806 LOC103151779 LOC103151779 ENSPFOP00000003275 ENSPFOP00000003275 rad50 rad50 PRKAB2 PRKAB2 ENSPFOP00000003440 ENSPFOP00000003440 ENSPFOP00000003961 ENSPFOP00000003961 LOC103132215 LOC103132215 rpa1 rpa1 ENSPFOP00000004561 ENSPFOP00000004561 aurka aurka ENSPFOP00000004680 ENSPFOP00000004680 brca1 brca1 ENSPFOP00000004707 ENSPFOP00000004707 exd2 exd2 hus1 hus1 LOC103142380 LOC103142380 slf1 slf1 blm blm LOC103143028 LOC103143028 ankrd11 ankrd11 LOC103145803 LOC103145803 mapkapk5 mapkapk5 rfc4 rfc4 taf5 taf5 recql4 recql4 rfc2 rfc2 ENSPFOP00000006168 ENSPFOP00000006168 ENSPFOP00000007192 ENSPFOP00000007192 taf2 taf2 tp53 tp53 LOC103150981 LOC103150981 cdk2 cdk2 hipk2 hipk2 ENSPFOP00000008593 ENSPFOP00000008593 LOC103145653 LOC103145653 rad1 rad1 nuak1 nuak1 rpa3 rpa3 taf11 taf11 ssrp1 ssrp1 LOC103141875 LOC103141875 rad9a rad9a TAF4 TAF4 kat5 kat5 LOC103142493 LOC103142493 ENSPFOP00000010827 ENSPFOP00000010827 PRKAG2 PRKAG2 CSNK2A2 CSNK2A2 taf10 taf10 prkab1 prkab1 ENSPFOP00000011757 ENSPFOP00000011757 chek2 chek2 dyrk4 dyrk4 LOC103152715 LOC103152715 rmi2 rmi2 taf5l taf5l RPA1 RPA1 rps27a rps27a taf3 taf3 cdk5 cdk5 ENSPFOP00000013293 ENSPFOP00000013293 cdca7 cdca7 ENSPFOP00000013687 ENSPFOP00000013687 taf7 taf7 LOC103141200 LOC103141200 rpa2 rpa2 ENSPFOP00000014349 ENSPFOP00000014349 ENSPFOP00000014359 ENSPFOP00000014359 rfc3 rfc3 LOC103149224 LOC103149224 ENSPFOP00000014732 ENSPFOP00000014732 taf12 taf12 ENSPFOP00000014766 ENSPFOP00000014766 ENSPFOP00000014830 ENSPFOP00000014830 rfc5 rfc5 ENSPFOP00000015340 ENSPFOP00000015340 prkaa1 prkaa1 prkaa2 prkaa2 ENSPFOP00000015694 ENSPFOP00000015694 LOC103153544 LOC103153544 nbn nbn dyrk3 dyrk3 rhno1 rhno1 LOC103133711 LOC103133711 LOC103134676 LOC103134676 mdm4 mdm4 mdm2 mdm2 ENSPFOP00000017410 ENSPFOP00000017410 tpx2 tpx2 cdk5r1 cdk5r1 ccna2 ccna2 LOC103149938 LOC103149938 chek1 chek1 ubb ubb ENSPFOP00000018931 ENSPFOP00000018931 ENSPFOP00000019162 ENSPFOP00000019162 topbp1 topbp1 cdk5r2 cdk5r2 taf13 taf13 LOC103143475 LOC103143475 ENSPFOP00000021113 ENSPFOP00000021113 ENSPFOP00000021474 ENSPFOP00000021474
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPFOP00000021872RAD9 checkpoint clamp component B. (369 aa)
ENSPFOP00000022327Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (256 aa)
ENSPFOP00000023184Uncharacterized protein. (679 aa)
hipk3Homeodomain interacting protein kinase 3b. (1344 aa)
LOC103144355Mitogen-activated protein kinase. (360 aa)
tdrd3Tudor domain containing 3. (786 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (334 aa)
ENSPFOP00000026321Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (407 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (299 aa)
ENSPFOP00000030916Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (308 aa)
ENSPFOP00000000215RAD17 checkpoint clamp loader component. (627 aa)
nuak2NUAK family, SNF1-like kinase, 2. (606 aa)
LOC103130849TAFH domain-containing protein. (921 aa)
LOC103139502Si:ch211-160o17.4. (1147 aa)
ENSPFOP00000000831Uncharacterized protein. (127 aa)
LOC103155213Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (350 aa)
ENSPFOP00000001063Uncharacterized protein. (294 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC103152767Mitogen-activated protein kinase. (364 aa)
dyrk2Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (590 aa)
cdca7lCell division cycle associated 7b. (401 aa)
LOC103154558Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1030 aa)
exo1Exonuclease 1. (769 aa)
ankrd12Ankyrin repeat domain 12. (1822 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (331 aa)
ENSPFOP00000002713Aurora kinase B; Belongs to the protein kinase superfamily. (285 aa)
ENSPFOP00000002806TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (252 aa)
LOC103151779Mitogen-activated protein kinase. (361 aa)
ENSPFOP00000003275Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (722 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (267 aa)
ENSPFOP00000003440TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1725 aa)
ENSPFOP00000003961Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (216 aa)
LOC103132215Ubiquitin-like domain-containing protein. (331 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
ENSPFOP00000004561Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (427 aa)
ENSPFOP00000004680Peptidyl-prolyl cis-trans isomerase. (217 aa)
brca1Uncharacterized protein. (1316 aa)
ENSPFOP00000004707Zgc:86598; Belongs to the protein kinase superfamily. (408 aa)
exd2Exonuclease 3'-5' domain containing 2. (639 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
LOC103142380RPA_C domain-containing protein. (255 aa)
slf1SMC5-SMC6 complex localization factor 1. (880 aa)
blmBLM RecQ like helicase. (1366 aa)
LOC103143028Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (544 aa)
ankrd11Ankyrin repeat domain 11. (2825 aa)
LOC103145803TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (850 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
taf5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (745 aa)
recql4RecQ helicase-like 4. (1494 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
ENSPFOP00000006168ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3081 aa)
ENSPFOP00000007192Uncharacterized protein. (246 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1219 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (342 aa)
LOC103150981Homeodomain interacting protein kinase 1a. (1102 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
hipk2Homeodomain interacting protein kinase 2. (1225 aa)
ENSPFOP00000008593Uncharacterized protein. (227 aa)
LOC103145653TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (637 aa)
rad1RAD1 homolog (S. pombe). (279 aa)
nuak1NUAK family, SNF1-like kinase, 1b. (661 aa)
rpa3Replication protein A3. (122 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (208 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
LOC103141875Si:ch211-117c9.1. (702 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa)
TAF4TATA-box binding protein associated factor 4. (856 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (560 aa)
LOC103142493Protein kinase domain-containing protein. (1352 aa)
ENSPFOP00000010827TBP-like 1. (126 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (494 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
taf10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
prkab1Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
ENSPFOP00000011757TP53 regulating kinase. (230 aa)
chek2Checkpoint kinase 2. (514 aa)
dyrk4Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (595 aa)
LOC103152715Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (390 aa)
rmi2RecQ mediated genome instability 2. (146 aa)
taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (601 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (591 aa)
rps27aRibosomal protein S27a. (156 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (942 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSPFOP00000013293Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (269 aa)
cdca7Cell division cycle associated 7a. (401 aa)
ENSPFOP00000013687ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2661 aa)
taf7TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (362 aa)
LOC103141200Mitogen-activated protein kinase. (357 aa)
rpa2Replication protein A2. (278 aa)
ENSPFOP00000014349TAFH domain-containing protein. (953 aa)
ENSPFOP00000014359Methionine sulfoxide reductase B1b. (471 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
LOC103149224Cyclin-dependent kinase 5 activator. (334 aa)
ENSPFOP00000014732TAFH domain-containing protein. (1080 aa)
taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (131 aa)
ENSPFOP00000014766DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (977 aa)
ENSPFOP00000014830TATA box binding protein. (315 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSPFOP00000015340Uncharacterized protein. (1194 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
ENSPFOP00000015694Cyclin A1; Belongs to the cyclin family. (419 aa)
LOC103153544Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa)
nbnNibrin. (843 aa)
dyrk3Dual specificity tyrosine phosphorylation regulated kinase 3. (576 aa)
rhno1Si:ch73-352p4.5. (291 aa)
LOC103133711KxDL motif containing 1. (185 aa)
LOC103134676Uncharacterized protein. (763 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (490 aa)
mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (471 aa)
ENSPFOP00000017410Uncharacterized protein. (573 aa)
tpx2TPX2 microtubule nucleation factor. (681 aa)
cdk5r1Cyclin-dependent kinase 5 activator. (308 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
LOC103149938Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (401 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa)
ubbUbiquitin B. (259 aa)
ENSPFOP00000018931RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (642 aa)
ENSPFOP00000019162NOC2-like nucleolar associated transcriptional repressor. (743 aa)
topbp1DNA topoisomerase II binding protein 1. (1515 aa)
cdk5r2Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (290 aa)
taf13TATA-box binding protein associated factor 13. (125 aa)
LOC103143475Cyclin-dependent kinase 5 activator. (323 aa)
ENSPFOP00000021113Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (183 aa)
ENSPFOP00000021474Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (344 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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