STRINGSTRING
ENSPFOP00000007723 ENSPFOP00000007723 tp53 tp53 LOC103146504 LOC103146504 LOC103145381 LOC103145381 LOC103153494 LOC103153494 ENSPFOP00000006168 ENSPFOP00000006168 LOC103146770 LOC103146770 ENSPFOP00000025356 ENSPFOP00000025356 ENSPFOP00000019888 ENSPFOP00000019888 LOC103134364 LOC103134364 ubb ubb ccna2 ccna2 prdm1 prdm1 mdm2 mdm2 mdm4 mdm4 LOC103133711 LOC103133711 rictor rictor LOC103145516 LOC103145516 LOC103131405 LOC103131405 LOC103145819 LOC103145819 ENSPFOP00000015694 ENSPFOP00000015694 ENSPFOP00000015636 ENSPFOP00000015636 CDK1 CDK1 ENSPFOP00000015551 ENSPFOP00000015551 ENSPFOP00000015344 ENSPFOP00000015344 ENSPFOP00000015266 ENSPFOP00000015266 mlst8 mlst8 ENSPFOP00000013453 ENSPFOP00000013453 rps27a rps27a LOC103137460 LOC103137460 PPP2CA PPP2CA chek2 chek2 rffl rffl ENSPFOP00000010964 ENSPFOP00000010964 ccng1 ccng1 akt1 akt1 usp7 usp7 mapkap1 mapkap1 ENSPFOP00000000777 ENSPFOP00000000777 uba52 uba52 LOC103146385 LOC103146385 ENSPFOP00000003054 ENSPFOP00000003054 LOC103132215 LOC103132215 mtor mtor ppp2r1b ppp2r1b ppp2ca ppp2ca LOC103140705 LOC103140705 cdk2 cdk2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPFOP00000007723PHD finger protein 20, a. (1001 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (342 aa)
LOC103146504Uncharacterized protein. (471 aa)
LOC103145381Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC103153494C2H2-type domain-containing protein. (752 aa)
ENSPFOP00000006168ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3081 aa)
LOC103146770Ring finger protein 34a. (368 aa)
ENSPFOP00000025356Uncharacterized protein. (182 aa)
ENSPFOP00000019888Ring finger protein 34b. (410 aa)
LOC103134364Uncharacterized protein. (783 aa)
ubbUbiquitin B. (259 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
prdm1PR domain containing 1a, with ZNF domain. (844 aa)
mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (471 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (490 aa)
LOC103133711KxDL motif containing 1. (185 aa)
rictorRPTOR independent companion of MTOR, complex 2 a. (1666 aa)
LOC103145516Ubiquitin carboxyl-terminal hydrolase. (399 aa)
LOC103131405Serine/threonine-protein phosphatase. (309 aa)
LOC103145819PHD finger protein 20-like. (1001 aa)
ENSPFOP00000015694Cyclin A1; Belongs to the cyclin family. (419 aa)
ENSPFOP00000015636Cyclin-dependent kinase 1. (304 aa)
CDK1Cyclin-dependent kinase 1. (303 aa)
ENSPFOP00000015551Cyclin-dependent kinase 1. (302 aa)
ENSPFOP000000153443-phosphoinositide dependent protein kinase 1b. (318 aa)
ENSPFOP000000152663-phosphoinositide dependent protein kinase 1b. (567 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
ENSPFOP00000013453Thioredoxin domain containing 11. (826 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC103137460Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
chek2Checkpoint kinase 2. (514 aa)
rfflRing finger and FYVE-like domain containing E3 ubiquitin protein ligase. (344 aa)
ENSPFOP00000010964Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
ccng1Cyclin G1; Belongs to the cyclin family. (297 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1110 aa)
mapkap1MAPK associated protein 1. (525 aa)
ENSPFOP00000000777Non-specific serine/threonine protein kinase. (522 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC103146385Death-domain associated protein. (721 aa)
ENSPFOP00000003054PR domain containing 1b, with ZNF domain. (647 aa)
LOC103132215Ubiquitin-like domain-containing protein. (331 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC103140705Ubiquitin carboxyl-terminal hydrolase. (586 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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