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| | wee1 | Wee1-like protein kinase. (620 aa) |
| | LOC103130966 | Proteasome 26S subunit, non-ATPase 4a. (372 aa) |
| | LOC103133374-5 | Histone H4. (103 aa) |
| | LOC103154042-3 | Histone H2B 1/2-like. (124 aa) |
| | LOC103154042-2 | Histone H2B 1/2-like. (124 aa) |
| | LOC103133374-4 | Histone H4. (103 aa) |
| | LOC103144613-3 | Histone H2B 1/2. (124 aa) |
| | LOC103144613-2 | Histone H2B 1/2. (124 aa) |
| | ENSPFOP00000020763 | BRCA1/BRCA2-containing complex, subunit 3. (266 aa) |
| | ENSPFOP00000020401 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC103153205 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC103133374-3 | Histone H4. (103 aa) |
| | LOC103133374-2 | Histone H4. (103 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1515 aa) |
| | psmf1 | Proteasome inhibitor subunit 1. (272 aa) |
| | ENSPFOP00000019062 | Proteasome subunit alpha type. (235 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (514 aa) |
| | ENSPFOP00000018931 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (642 aa) |
| | ENSPFOP00000018798 | Proteasome subunit beta11b. (343 aa) |
| | ubb | Ubiquitin B. (259 aa) |
| | ENSPFOP00000018736 | Proteasome subunit alpha type. (258 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa) |
| | psmd9 | Proteasome 26S subunit, non-ATPase 9. (212 aa) |
| | ccnb1 | Cyclin B1; Belongs to the cyclin family. (401 aa) |
| | LOC103151986 | Proteasome 26S subunit, non-ATPase 11b. (423 aa) |
| | LOC103130469 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC103151127 | Cyclin B2; Belongs to the cyclin family. (385 aa) |
| | LOC103154042 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | psmd7 | Proteasome 26S subunit, non-ATPase 7. (330 aa) |
| | psma5 | Proteasome subunit alpha type. (283 aa) |
| | psme3 | Proteasome activator subunit 3. (257 aa) |
| | ENSPFOP00000017410 | Uncharacterized protein. (573 aa) |
| | LOC103134676 | Uncharacterized protein. (763 aa) |
| | ENSPFOP00000017291 | Cell division cycle 7 homolog (S. cerevisiae); Belongs to the protein kinase superfamily. (484 aa) |
| | ENSPFOP00000017246 | Proteasome subunit beta. (206 aa) |
| | LOC103133711 | KxDL motif containing 1. (185 aa) |
| | ENSPFOP00000014388 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | ENSPFOP00000014359 | Methionine sulfoxide reductase B1b. (471 aa) |
| | rpa2 | Replication protein A2. (278 aa) |
| | orc3 | Origin recognition complex, subunit 3. (726 aa) |
| | psma6 | Proteasome subunit alpha type. (246 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (871 aa) |
| | ENSPFOP00000013687 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2661 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (863 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa) |
| | LOC103138354 | DNA helicase; Belongs to the MCM family. (825 aa) |
| | ENSPFOP00000017052 | Proteasome subunit beta. (271 aa) |
| | LOC103145510 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (326 aa) |
| | nbn | Nibrin. (843 aa) |
| | LOC103135972 | Proteasome subunit alpha type. (261 aa) |
| | UBE2N | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (163 aa) |
| | psmd14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | orc5 | Origin recognition complex, subunit 5. (442 aa) |
| | dbf4 | DBF4 zinc finger. (597 aa) |
| | wee2 | Wee1-like protein kinase. (554 aa) |
| | ENSPFOP00000011005 | BRISC and BRCA1 A complex member 2. (331 aa) |
| | ywhaz | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa) |
| | psmb4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa) |
| | rnf169 | Ring finger protein 169. (574 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (560 aa) |
| | psme1 | Proteasome activator subunit 1. (250 aa) |
| | ENSPFOP00000010038 | Rhodanese domain-containing protein. (572 aa) |
| | psmd6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | psmd3 | Proteasome 26S subunit, non-ATPase 3. (527 aa) |
| | ENSPFOP00000000215 | RAD17 checkpoint clamp loader component. (627 aa) |
| | ENSPFOP00000000479 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (253 aa) |
| | psmd13 | Proteasome 26S subunit, non-ATPase 13. (378 aa) |
| | PIEZO2 | Piezo-type mechanosensitive ion channel component. (2971 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (509 aa) |
| | ENSPFOP00000001482 | Proteasome activator subunit 2. (251 aa) |
| | cdca7l | Cell division cycle associated 7b. (401 aa) |
| | psmb2 | Proteasome subunit beta. (199 aa) |
| | CLSPN | Claspin. (1195 aa) |
| | LOC103144613 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | psmc2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | psma8 | Proteasome subunit alpha type. (251 aa) |
| | ENSPFOP00000002331 | Abraxas 1, BRCA1 A complex subunit. (350 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa) |
| | exo1 | Exonuclease 1. (769 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1822 aa) |
| | ENSPFOP00000002543 | Proteasome subunit beta. (276 aa) |
| | LOC103155941 | Proteasome subunit alpha type. (246 aa) |
| | LOC103146403 | Proteasome subunit beta. (216 aa) |
| | ENSPFOP00000003275 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (722 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | LOC103153226 | Proteasome subunit beta. (278 aa) |
| | ENSPFOP00000003632 | Nuclear receptor binding SET domain protein 2. (1301 aa) |
| | psmd5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) |
| | ENSPFOP00000004459 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (573 aa) |
| | cdca7 | Cell division cycle associated 7a. (401 aa) |
| | ENSPFOP00000013373 | Proteasome 26S subunit, non-ATPase 12. (462 aa) |
| | ENSPFOP00000013426 | Histone H2B; Belongs to the histone H2B family. (122 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | cdc6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (586 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (591 aa) |
| | LOC103149670 | Proteasome subunit alpha type. (246 aa) |
| | rmi2 | RecQ mediated genome instability 2. (146 aa) |
| | chek2 | Checkpoint kinase 2. (514 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (886 aa) |
| | psmc1 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa) |
| | ENSPFOP00000011703 | Proteasome 26S subunit, non-ATPase 8. (267 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (571 aa) |
| | LOC103145207 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa) |
| | ENSPFOP00000021397 | Reverse transcriptase domain-containing protein. (784 aa) |
| | ENSPFOP00000021872 | RAD9 checkpoint clamp component B. (369 aa) |
| | ENSPFOP00000023184 | Uncharacterized protein. (679 aa) |
| | ENSPFOP00000023229 | Uncharacterized protein. (235 aa) |
| | ENSPFOP00000023669 | Proteasome subunit beta 7. (143 aa) |
| | tdrd3 | Tudor domain containing 3. (786 aa) |
| | ENSPFOP00000025830 | Uncharacterized protein. (2090 aa) |
| | LOC103143686 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | LOC103130469-2 | Histone H2B 1/2-like. (124 aa) |
| | LOC103140822 | Proteasome 26S subunit, non-ATPase 4b. (375 aa) |
| | ENSPFOP00000028041 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (390 aa) |
| | ENSPFOP00000028055 | Reverse transcriptase domain-containing protein. (432 aa) |
| | ENSPFOP00000028108 | Uncharacterized protein. (799 aa) |
| | wdr41 | WD repeat domain 41. (447 aa) |
| | ENSPFOP00000028950 | Reverse transcriptase domain-containing protein. (609 aa) |
| | ENSPFOP00000029491 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa) |
| | LOC103146405 | Proteasome subunit beta 12. (222 aa) |
| | psmd1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa) |
| | ENSPFOP00000031142 | Proteasome subunit beta 7. (166 aa) |
| | ENSPFOP00000031155 | Piezo_RRas_bdg domain-containing protein. (174 aa) |
| | LOC103129309 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | rhno1 | Si:ch73-352p4.5. (291 aa) |
| | ENSPFOP00000017041 | Proteasome subunit beta. (254 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (868 aa) |
| | psme4 | Proteasome activator subunit 4a. (1850 aa) |
| | PSMD11 | PCI domain-containing protein. (422 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (827 aa) |
| | psmc6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) |
| | ENSPFOP00000014766 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (977 aa) |
| | orc2 | Origin recognition complex, subunit 2. (586 aa) |
| | psmb1 | Proteasome subunit beta. (237 aa) |
| | psmc3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa) |
| | psmc4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa) |
| | ENSPFOP00000014868 | Piezo-type mechanosensitive ion channel component. (2525 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (954 aa) |
| | ENSPFOP00000015340 | Uncharacterized protein. (1194 aa) |
| | LOC103133374 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | ENSPFOP00000015551 | Cyclin-dependent kinase 1. (302 aa) |
| | CDK1 | Cyclin-dependent kinase 1. (303 aa) |
| | psmc5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | ENSPFOP00000015636 | Cyclin-dependent kinase 1. (304 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (382 aa) |
| | ENSPFOP00000004669 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (861 aa) |
| | brca1 | Uncharacterized protein. (1316 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | LOC103142380 | RPA_C domain-containing protein. (255 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (880 aa) |
| | ywhaq | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (249 aa) |
| | blm | BLM RecQ like helicase. (1366 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2825 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | ccnb3 | Cyclin B3; Belongs to the cyclin family. (430 aa) |
| | LOC103151589 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (250 aa) |
| | LOC103152057 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) |
| | recql4 | RecQ helicase-like 4. (1494 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | ENSPFOP00000006168 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3081 aa) |
| | rnf168 | Ring finger protein 168. (431 aa) |
| | LOC103147141 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa) |
| | psmd10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | pkmyt1 | Protein kinase, membrane associated tyrosine/threonine 1. (578 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (342 aa) |
| | ENSPFOP00000007732 | Piezo-type mechanosensitive ion channel component. (2754 aa) |
| | LOC103132800 | Proteasome subunit beta. (233 aa) |
| | LOC103132650 | Tumor protein p53 binding protein, 1. (1538 aa) |
| | ENSPFOP00000008051 | Uncharacterized protein. (1839 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | LOC103143238 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | LOC103148522 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) |
| | ENSPFOP00000008567 | Proteasome subunit alpha type. (263 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | LOC103142066 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa) |
