STRINGSTRING
ENSPFOP00000030074 ENSPFOP00000030074 l2hgdh l2hgdh dlat dlat LOC103146159 LOC103146159 ogdh ogdh suclg2 suclg2 MDH2 MDH2 LOC103136570 LOC103136570 fh fh LOC103148176 LOC103148176 me1 me1 LOC103141539 LOC103141539 LOC103141533 LOC103141533 ENSPFOP00000019283 ENSPFOP00000019283 LOC103135426 LOC103135426 ENSPFOP00000019047 ENSPFOP00000019047 SDHB SDHB GLO1 GLO1 pdp2 pdp2 LOC103152008 LOC103152008 pdpr pdpr pdp1 pdp1 IDH2 IDH2 ENSPFOP00000017440 ENSPFOP00000017440 LOC103143296 LOC103143296 d2hgdh d2hgdh sdhd sdhd mpc1 mpc1 LOC103150475 LOC103150475 gstz1 gstz1 LOC103143312 LOC103143312 pnkd pnkd LOC103140321 LOC103140321 ENSPFOP00000014649 ENSPFOP00000014649 mpc2 mpc2 pdhx pdhx dld dld ACO2 ACO2 ppard ppard sdhc sdhc pdk1 pdk1 ENSPFOP00000012326 ENSPFOP00000012326 ENSPFOP00000012004 ENSPFOP00000012004 rxra rxra idh3b idh3b ENSPFOP00000011188 ENSPFOP00000011188 cs cs sucla2 sucla2 ENSPFOP00000010769 ENSPFOP00000010769 LOC103150656 LOC103150656 LACTB2 LACTB2 ENSPFOP00000010208 ENSPFOP00000010208 LOC103130055 LOC103130055 OGDH OGDH LOC103141643 LOC103141643 HAGHL HAGHL ldhb ldhb DLST DLST mblac2 mblac2 pdhb pdhb vdac1 vdac1 LOC103147849 LOC103147849 suclg1 suclg1 ENSPFOP00000005242 ENSPFOP00000005242 ENSPFOP00000004761 ENSPFOP00000004761 LOC103151604 LOC103151604 pdk3 pdk3 LOC103152207 LOC103152207 LOC103134408 LOC103134408 ENSPFOP00000000018 ENSPFOP00000000018
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ENSPFOP00000030074Fumarylacetoacetate hydrolase domain containing 1. (222 aa)
l2hgdhL-2-hydroxyglutarate dehydrogenase. (447 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
LOC103146159NAD(P) transhydrogenase, mitochondrial-like. (650 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1029 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
MDH2Malate dehydrogenase, mitochondrial. (337 aa)
LOC103136570Malate dehydrogenase. (337 aa)
fhFumarate hydratase. (499 aa)
LOC103148176Nicotinamide nucleotide transhydrogenase. (1087 aa)
me1Malic enzyme. (588 aa)
LOC103141539Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
LOC103141533Uncharacterized protein. (608 aa)
ENSPFOP00000019283Malic enzyme. (559 aa)
LOC103135426Malic enzyme. (582 aa)
ENSPFOP00000019047Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
pdp2Putative pyruvate dehydrogenase phosphatase isoenzyme 2. (527 aa)
LOC103152008Protein-serine/threonine kinase. (408 aa)
pdprPyruvate dehydrogenase phosphatase regulatory subunit. (892 aa)
pdp1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (523 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (453 aa)
ENSPFOP00000017440Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (191 aa)
LOC103143296Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
d2hgdhD-2-hydroxyglutarate dehydrogenase. (536 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (157 aa)
mpc1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (88 aa)
LOC103150475Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa)
gstz1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (220 aa)
LOC103143312Uncharacterized protein; Belongs to the GST superfamily. (226 aa)
pnkdSi:ch73-71c20.5. (150 aa)
LOC103140321Malic enzyme. (618 aa)
ENSPFOP00000014649Dihydrolipoamide S-succinyltransferase. (508 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (123 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (783 aa)
ppardPeroxisome proliferator-activated receptor delta b. (508 aa)
sdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (169 aa)
pdk1Protein-serine/threonine kinase. (412 aa)
ENSPFOP00000012326Si:ch211-15p9.2. (464 aa)
ENSPFOP00000012004Protein-serine/threonine kinase. (420 aa)
rxraRetinoid X receptor, alpha a. (496 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
ENSPFOP00000011188Family with sequence similarity 114 member A1. (594 aa)
csCitrate synthase; Belongs to the citrate synthase family. (469 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
ENSPFOP00000010769Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (351 aa)
LOC103150656PNKD metallo-beta-lactamase domain containing. (360 aa)
LACTB2Lactamase beta 2. (287 aa)
ENSPFOP00000010208Alcohol dehydrogenase iron containing 1. (469 aa)
LOC103130055Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
OGDHOxoglutarate dehydrogenase. (1022 aa)
LOC103141643Hydroxyacylglutathione hydrolase. (309 aa)
HAGHLHydroxyacylglutathione hydrolase like. (290 aa)
ldhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
DLSTDihydrolipoamide S-succinyltransferase. (447 aa)
mblac2Metallo-beta-lactamase domain containing 2. (276 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
LOC103147849Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
ENSPFOP00000005242Nicotinamide nucleotide transhydrogenase 2. (1072 aa)
ENSPFOP00000004761Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
LOC103151604L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
pdk3Protein-serine/threonine kinase. (407 aa)
LOC103152207Voltage-dependent anion channel 1. (252 aa)
LOC103134408L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (355 aa)
ENSPFOP00000000018Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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