13 items (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	disp2	Dispatched homolog 2 (Drosophila). (1469 aa)
	ENSPFOP00000021252	3-hydroxy-3-methylglutaryl coenzyme A reductase. (815 aa)
	ptch1	Patched 1. (1559 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1279 aa)
	scap	SREBF chaperone. (1313 aa)
	ENSPFOP00000012499	Patched domain containing 4. (628 aa)
	npc1	Niemann-Pick disease, type C1. (1277 aa)
	LOC103135855	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	ENSPFOP00000007191	SSD domain-containing protein. (547 aa)
	ENSPFOP00000003410	Patched domain containing 1. (934 aa)
	ENSPFOP00000003466	Patched domain containing 1. (916 aa)
	LOC103132185	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	ptch2	Patched 2. (1491 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000021252	LOC103132185	ENSPFOP00000021252	ENSPFOP00000005251	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.895
ENSPFOP00000021252	LOC103135855	ENSPFOP00000021252	ENSPFOP00000009402	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.895
LOC103132185	ENSPFOP00000021252	ENSPFOP00000005251	ENSPFOP00000021252	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.895
LOC103135855	ENSPFOP00000021252	ENSPFOP00000009402	ENSPFOP00000021252	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.895
ptch1	ptch2	ENSPFOP00000019445	ENSPFOP00000005818	Patched 1.	Patched 2.	0.926
ptch2	ptch1	ENSPFOP00000005818	ENSPFOP00000019445	Patched 2.	Patched 1.	0.926