(41 nodes) Other glycan degradation network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103139033	Biorientation of chromosomes in cell division 1. (162 aa)
	LOC103137808	Beta-galactosidase. (653 aa)
	rabggtb	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (331 aa)
	tmem130	PKD domain-containing protein. (308 aa)
	ENSPFOP00000002641	Uncharacterized protein. (1896 aa)
	ENSPFOP00000002735	Uncharacterized protein. (297 aa)
	ENSPFOP00000003648	Beta-galactosidase. (643 aa)
	ENSPFOP00000003854	Beta-galactosidase. (650 aa)
	gba2	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (863 aa)
	LOC103141324	Beta-hexosaminidase. (540 aa)
	LOC103150598	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family. (634 aa)
	ENSPFOP00000007100	Sialidase domain-containing protein. (380 aa)
	ENSPFOP00000007117	Sialidase domain-containing protein. (392 aa)
	LOC103139024	Stanniocalcin 2b. (263 aa)
	manba	Mannosidase, beta A, lysosomal. (892 aa)
	man2c1	Mannosidase, alpha, class 2C, member 1. (1022 aa)
	NEU1	Neuraminidase 1. (408 aa)
	LOC103136352	Sialidase 4. (474 aa)
	LOC103148459	Beta-galactosidase. (653 aa)
	ENSPFOP00000012358	Beta-hexosaminidase. (548 aa)
	man2b2	Alpha-mannosidase. (1014 aa)
	ENSPFOP00000013390	Sialidase domain-containing protein. (404 aa)
	man2b1	Alpha-mannosidase. (989 aa)
	gba	Glucosylceramidase. (522 aa)
	ENSPFOP00000015305	Beta-galactosidase. (637 aa)
	fuca1	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (447 aa)
	fuca2	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (455 aa)
	hexd	Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing. (479 aa)
	FAM149B1	Family with sequence similarity 149 member B1. (616 aa)
	FAM149B1-2	DUF3719 domain-containing protein. (647 aa)
	ENSPFOP00000018799	Family with sequence similarity 149 member B1. (642 aa)
	ENSPFOP00000018912	Sialidase domain-containing protein. (374 aa)
	ENSPFOP00000031083	annotation not available (207 aa)
	LOC103151754	Sialidase domain-containing protein. (389 aa)
	ENSPFOP00000018950	Sialidase domain-containing protein. (382 aa)
	ENSPFOP00000018990	Aspartylglucosaminidase. (329 aa)
	LOC103141778	Sialidase 3 (membrane sialidase), tandem duplicate 1. (410 aa)
	ENSPFOP00000027107	Stanniocalcin 2b. (235 aa)
	ENSPFOP00000026384	Neuraminidase 1. (302 aa)
	engase	Endo-beta-N-acetylglucosaminidase. (724 aa)
	ENSPFOP00000023348	Glyco_hydro_38N domain-containing protein. (107 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000002641	ENSPFOP00000012358	ENSPFOP00000002641	ENSPFOP00000012358	Uncharacterized protein.	Beta-hexosaminidase.	0.554
ENSPFOP00000002641	ENSPFOP00000018799	ENSPFOP00000002641	ENSPFOP00000018799	Uncharacterized protein.	Family with sequence similarity 149 member B1.	0.533
ENSPFOP00000002641	ENSPFOP00000026384	ENSPFOP00000002641	ENSPFOP00000026384	Uncharacterized protein.	Neuraminidase 1.	0.719
ENSPFOP00000002641	FAM149B1	ENSPFOP00000002641	ENSPFOP00000018753	Uncharacterized protein.	Family with sequence similarity 149 member B1.	0.533
ENSPFOP00000002641	FAM149B1-2	ENSPFOP00000002641	ENSPFOP00000018782	Uncharacterized protein.	DUF3719 domain-containing protein.	0.533
ENSPFOP00000002641	LOC103141324	ENSPFOP00000002641	ENSPFOP00000006629	Uncharacterized protein.	Beta-hexosaminidase.	0.554
ENSPFOP00000002641	NEU1	ENSPFOP00000002641	ENSPFOP00000010686	Uncharacterized protein.	Neuraminidase 1.	0.719
ENSPFOP00000002641	gba	ENSPFOP00000002641	ENSPFOP00000014282	Uncharacterized protein.	Glucosylceramidase.	0.644
ENSPFOP00000002641	gba2	ENSPFOP00000002641	ENSPFOP00000006238	Uncharacterized protein.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.522
ENSPFOP00000002641	manba	ENSPFOP00000002641	ENSPFOP00000008542	Uncharacterized protein.	Mannosidase, beta A, lysosomal.	0.634
ENSPFOP00000002641	tmem130	ENSPFOP00000002641	ENSPFOP00000001905	Uncharacterized protein.	PKD domain-containing protein.	0.644
ENSPFOP00000002735	ENSPFOP00000012358	ENSPFOP00000002735	ENSPFOP00000012358	Uncharacterized protein.	Beta-hexosaminidase.	0.554
ENSPFOP00000002735	ENSPFOP00000018799	ENSPFOP00000002735	ENSPFOP00000018799	Uncharacterized protein.	Family with sequence similarity 149 member B1.	0.533
ENSPFOP00000002735	ENSPFOP00000026384	ENSPFOP00000002735	ENSPFOP00000026384	Uncharacterized protein.	Neuraminidase 1.	0.719
ENSPFOP00000002735	FAM149B1	ENSPFOP00000002735	ENSPFOP00000018753	Uncharacterized protein.	Family with sequence similarity 149 member B1.	0.533
ENSPFOP00000002735	FAM149B1-2	ENSPFOP00000002735	ENSPFOP00000018782	Uncharacterized protein.	DUF3719 domain-containing protein.	0.533
ENSPFOP00000002735	LOC103141324	ENSPFOP00000002735	ENSPFOP00000006629	Uncharacterized protein.	Beta-hexosaminidase.	0.554
ENSPFOP00000002735	NEU1	ENSPFOP00000002735	ENSPFOP00000010686	Uncharacterized protein.	Neuraminidase 1.	0.719
ENSPFOP00000002735	gba	ENSPFOP00000002735	ENSPFOP00000014282	Uncharacterized protein.	Glucosylceramidase.	0.644
ENSPFOP00000002735	gba2	ENSPFOP00000002735	ENSPFOP00000006238	Uncharacterized protein.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.522