45 items (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000021252	3-hydroxy-3-methylglutaryl coenzyme A reductase. (815 aa)
	pcyox1l	Prenylcysteine oxidase 1 like. (501 aa)
	dhdds	Alkyl transferase; Belongs to the UPP synthase family. (335 aa)
	LOC103132185	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	KIF18A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (907 aa)
	hmgcs1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (519 aa)
	ENSPFOP00000003480	Uncharacterized protein. (111 aa)
	LOC103148254	RUN domain-containing protein. (1167 aa)
	ENSPFOP00000025881	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (380 aa)
	fnta	Farnesyltransferase, CAAX box, alpha. (368 aa)
	slc35f2	Solute carrier family 35 member F2. (372 aa)
	FBXO40	F-box protein 40. (690 aa)
	ENSPFOP00000025837	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (508 aa)
	pcyox1	Prenylcysteine oxidase 1. (509 aa)
	LOC103134931	Uncharacterized protein. (739 aa)
	ENSPFOP00000019545	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
	ggps1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (315 aa)
	churc1	Churchill domain containing 1. (112 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (404 aa)
	LOC103130771	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (432 aa)
	icmt	Protein-S-isoprenylcysteine O-methyltransferase. (291 aa)
	tomm70	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (578 aa)
	ENSPFOP00000015593	Abhydrolase_3 domain-containing protein. (369 aa)
	LOC103137064	OMA1 zinc metallopeptidase. (508 aa)
	LOC103129772-2	acetyl-CoA acetyltransferase, mitochondrial. (420 aa)
	LOC103129772	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
	LOC103144688	F-box protein 30a. (710 aa)
	nus1	NUS1 dehydrodolichyl diphosphate synthase subunit. (288 aa)
	LOC103146486-2	Zinc finger, C3HC-type containing 1. (495 aa)
	fdps	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)
	LOC103146567	Uncharacterized protein. (133 aa)
	LOC103148648	Uncharacterized protein. (102 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	pdss2	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (385 aa)
	idi1	Isopentenyl-diphosphate delta isomerase 1. (286 aa)
	LOC103138340	Info solute carrier family 35 member F2, like. (386 aa)
	ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1. (1004 aa)
	LOC103131722	Uncharacterized protein. (130 aa)
	ENSPFOP00000011785	Ras converting CAAX endopeptidase 1a. (300 aa)
	rusc2	RUN and SH3 domain containing 2. (1575 aa)
	LOC103135855	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	pmvk	Phosphomevalonate kinase. (264 aa)
	ENSPFOP00000008457	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (448 aa)
	ENSPFOP00000025013	Uncharacterized protein. (1837 aa)
	ENSPFOP00000022697	Si:dkey-193c22.1. (372 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000003480	ENSPFOP00000025881	ENSPFOP00000003480	ENSPFOP00000025881	Uncharacterized protein.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.782
ENSPFOP00000003480	hmgcs1	ENSPFOP00000003480	ENSPFOP00000004218	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.980
ENSPFOP00000003480	mvd	ENSPFOP00000003480	ENSPFOP00000017909	Uncharacterized protein.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.580
ENSPFOP00000008457	ENSPFOP00000021252	ENSPFOP00000008457	ENSPFOP00000021252	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.495
ENSPFOP00000008457	ENSPFOP00000025013	ENSPFOP00000008457	ENSPFOP00000025013	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Uncharacterized protein.	0.732
ENSPFOP00000008457	ENSPFOP00000025881	ENSPFOP00000008457	ENSPFOP00000025881	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.425
ENSPFOP00000008457	FBXO40	ENSPFOP00000008457	ENSPFOP00000000644	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	F-box protein 40.	0.778
ENSPFOP00000008457	LOC103130771	ENSPFOP00000008457	ENSPFOP00000017853	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.947
ENSPFOP00000008457	LOC103132185	ENSPFOP00000008457	ENSPFOP00000005251	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.495
ENSPFOP00000008457	LOC103134931	ENSPFOP00000008457	ENSPFOP00000019727	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Uncharacterized protein.	0.778
ENSPFOP00000008457	LOC103135855	ENSPFOP00000008457	ENSPFOP00000009402	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.495
ENSPFOP00000008457	LOC103138340	ENSPFOP00000008457	ENSPFOP00000012751	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Info solute carrier family 35 member F2, like.	0.617
ENSPFOP00000008457	LOC103144688	ENSPFOP00000008457	ENSPFOP00000015003	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	F-box protein 30a.	0.778
ENSPFOP00000008457	LOC103146486-2	ENSPFOP00000008457	ENSPFOP00000003428	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Zinc finger, C3HC-type containing 1.	0.473
ENSPFOP00000008457	LOC103148254	ENSPFOP00000008457	ENSPFOP00000030904	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	RUN domain-containing protein.	0.732
ENSPFOP00000008457	churc1	ENSPFOP00000008457	ENSPFOP00000019299	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Churchill domain containing 1.	0.816
ENSPFOP00000008457	dhdds	ENSPFOP00000008457	ENSPFOP00000006075	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Alkyl transferase; Belongs to the UPP synthase family.	0.975
ENSPFOP00000008457	fdps	ENSPFOP00000008457	ENSPFOP00000014399	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.972
ENSPFOP00000008457	fnta	ENSPFOP00000008457	ENSPFOP00000003220	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Farnesyltransferase, CAAX box, alpha.	0.969
ENSPFOP00000008457	ggps1	ENSPFOP00000008457	ENSPFOP00000019544	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.960