STRINGSTRING
adcy7 adcy7 ENSPFOP00000014641 ENSPFOP00000014641 LOC103146574 LOC103146574 LOC103136753 LOC103136753 LOC103136751 LOC103136751 LOC103134902 LOC103134902 cga cga LOC103141200 LOC103141200 ENSPFOP00000014096 ENSPFOP00000014096 ENSPFOP00000014004 ENSPFOP00000014004 LOC103155142 LOC103155142 LOC103155140 LOC103155140 LOC103150346 LOC103150346 map3k4 map3k4 LOC103140402 LOC103140402 ENSPFOP00000013324 ENSPFOP00000013324 SRC SRC ENSPFOP00000012816 ENSPFOP00000012816 ENSPFOP00000012691 ENSPFOP00000012691 ELK3 ELK3 ENSPFOP00000012149 ENSPFOP00000012149 LOC103150707 LOC103150707 pld1 pld1 ENSPFOP00000011900 ENSPFOP00000011900 calm2-2 calm2-2 ENSPFOP00000011418 ENSPFOP00000011418 jmjd7 jmjd7 ENSPFOP00000010708 ENSPFOP00000010708 LOC103151778-2 LOC103151778-2 cacna1s cacna1s egfr egfr LOC103147148 LOC103147148 LOC103146449 LOC103146449 mmp14 mmp14 LOC103137428 LOC103137428 ENSPFOP00000009386 ENSPFOP00000009386 ptx3 ptx3 calm2 calm2 sos1 sos1 PLCB2 PLCB2 ENSPFOP00000009094 ENSPFOP00000009094 LOC103138634 LOC103138634 egr1 egr1 ENSPFOP00000008816 ENSPFOP00000008816 map2k1 map2k1 ENSPFOP00000008202 ENSPFOP00000008202 LOC103152558 LOC103152558 LOC103152577 LOC103152577 LOC103145420 LOC103145420 itpr1 itpr1 LOC103135541 LOC103135541 ENSPFOP00000007615 ENSPFOP00000007615 map2k7 map2k7 LOC103153057 LOC103153057 ENSPFOP00000006967 ENSPFOP00000006967 LOC103150940 LOC103150940 ENSPFOP00000006708 ENSPFOP00000006708 MAP2K6 MAP2K6 LOC103145637 LOC103145637 LOC103141622 LOC103141622 mapk1 mapk1 LOC103147315 LOC103147315 LOC103154846 LOC103154846 mapk10 mapk10 LOC103156750 LOC103156750 CACNA1D CACNA1D LOC103147384 LOC103147384 grb2 grb2 LOC103134016 LOC103134016 LOC103144386 LOC103144386 mapk7 mapk7 prkaca prkaca LOC103135537 LOC103135537 LOC103144092 LOC103144092 ENSPFOP00000004131 ENSPFOP00000004131 PLCB1 PLCB1 ENSPFOP00000003798 ENSPFOP00000003798 ENSPFOP00000003624 ENSPFOP00000003624 LOC103144528 LOC103144528 adcy3 adcy3 ENSPFOP00000003322 ENSPFOP00000003322 ENSPFOP00000003238 ENSPFOP00000003238 LOC103144631 LOC103144631 LOC103138590 LOC103138590 LOC103149084 LOC103149084 LOC103151779 LOC103151779 ENSPFOP00000002785 ENSPFOP00000002785 LOC103151778 LOC103151778 hras hras ENSPFOP00000002298 ENSPFOP00000002298 ENSPFOP00000002132 ENSPFOP00000002132 PLCB4 PLCB4 map2k2 map2k2 LOC103145765 LOC103145765 LOC103152767 LOC103152767 ENSPFOP00000001062 ENSPFOP00000001062 ENSPFOP00000000972 ENSPFOP00000000972 ADCY9 ADCY9 LOC103152501 LOC103152501 ENSPFOP00000000338 ENSPFOP00000000338 ENSPFOP00000023942 ENSPFOP00000023942 ENSPFOP00000024131 ENSPFOP00000024131 ENSPFOP00000024266 ENSPFOP00000024266 LOC103144355 LOC103144355 ENSPFOP00000025375 ENSPFOP00000025375 ENSPFOP00000025965 ENSPFOP00000025965 PRKCB PRKCB ENSPFOP00000027845 ENSPFOP00000027845 LOC103129836 LOC103129836 CDC42 CDC42 LOC103129281 LOC103129281 LOC103129619 LOC103129619 pla2g4a pla2g4a CSDE1 CSDE1 ENSPFOP00000030671 ENSPFOP00000030671 rrad rrad ADCY9-2 ADCY9-2 ENSPFOP00000022348 ENSPFOP00000022348 LOC103130823 LOC103130823 LOC103137045 LOC103137045 ENSPFOP00000020202 ENSPFOP00000020202 calm2-3 calm2-3 camk2a camk2a map2k4 map2k4 ENSPFOP00000019002 ENSPFOP00000019002 LOC103142608 LOC103142608 camk2b camk2b LOC103135363 LOC103135363 LOC103136016 LOC103136016 ENSPFOP00000017922 ENSPFOP00000017922 ENSPFOP00000017888 ENSPFOP00000017888 mapk8 mapk8 REM1 REM1 LOC103133557 LOC103133557 LOC103135989 LOC103135989 ENSPFOP00000017136 ENSPFOP00000017136 sos2 sos2 ENSPFOP00000017065 ENSPFOP00000017065 ENSPFOP00000016965 ENSPFOP00000016965 LOC103138402 LOC103138402 LOC103150485 LOC103150485 pla2g4c pla2g4c mmp2 mmp2 ENSPFOP00000016031 ENSPFOP00000016031 KRAS KRAS LOC103135793 LOC103135793
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
ENSPFOP00000014641Calmodulin-like 4a. (152 aa)
LOC103146574Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
LOC103136753Uncharacterized protein. (191 aa)
LOC103136751Uncharacterized protein. (191 aa)
LOC103134902Calcium/calmodulin dependent protein kinase II beta. (526 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (126 aa)
LOC103141200Mitogen-activated protein kinase. (357 aa)
ENSPFOP00000014096Mitogen-activated protein kinase kinase kinase 3. (617 aa)
ENSPFOP00000014004Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC103155142Uncharacterized protein. (351 aa)
LOC103155140G protein subunit alpha q. (359 aa)
LOC1031503461-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1573 aa)
LOC103140402Mitogen-activated protein kinase kinase kinase 22. (618 aa)
ENSPFOP00000013324annotation not available (148 aa)
SRCTyrosine-protein kinase. (550 aa)
ENSPFOP00000012816Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa)
ENSPFOP00000012691Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1193 aa)
ELK3ETS transcription factor ELK3. (400 aa)
ENSPFOP00000012149Adenylate cyclase 6b; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (891 aa)
LOC103150707Mitogen-activated protein kinase kinase 6. (381 aa)
pld1Phospholipase. (1061 aa)
ENSPFOP00000011900Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
calm2-2Calmodulin. (149 aa)
ENSPFOP00000011418Protein kinase domain-containing protein. (616 aa)
jmjd7Jumonji domain containing 7. (312 aa)
ENSPFOP00000010708Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (86 aa)
LOC103151778-2Mitogen-activated protein kinase 12-like. (362 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1845 aa)
egfrReceptor protein-tyrosine kinase. (1204 aa)
LOC103147148Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (942 aa)
LOC103146449Uncharacterized protein. (191 aa)
mmp14Matrix metallopeptidase 14a (membrane-inserted). (557 aa)
LOC103137428Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (539 aa)
ENSPFOP00000009386G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
ptx3Pentraxin 3, long b. (444 aa)
calm2Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1329 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
ENSPFOP00000009094Phospholipase. (959 aa)
LOC103138634Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (995 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
ENSPFOP00000008816Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
ENSPFOP00000008202Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
LOC103152558ETS transcription factor ELK3. (376 aa)
LOC103152577ETS transcription factor ELK3. (284 aa)
LOC103145420Zgc:55558. (187 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1a. (2693 aa)
LOC103135541Mitogen-activated protein kinase. (420 aa)
ENSPFOP000000076151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1224 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
LOC103153057GRB2 related adaptor protein 2a. (288 aa)
ENSPFOP00000006967Uncharacterized protein. (391 aa)
LOC103150940Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1180 aa)
ENSPFOP00000006708G_PROTEIN_RECEP_F1_2 domain-containing protein. (385 aa)
MAP2K6Mitogen-activated protein kinase kinase 6. (336 aa)
LOC103145637Phospholipase. (957 aa)
LOC103141622Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
LOC103147315Inositol 1,4,5-trisphosphate receptor, type 1b. (2426 aa)
LOC103154846Activating transcription factor 4a. (424 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
LOC103156750Receptor protein-tyrosine kinase. (1168 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2237 aa)
LOC103147384Activating transcription factor 4b. (448 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC103134016Mitogen-activated protein kinase. (460 aa)
LOC103144386Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1066 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
LOC103135537GNAS complex locus. (379 aa)
LOC103144092Cell division cycle 42. (191 aa)
ENSPFOP00000004131JunE proto-oncogene, AP-1 transcription factor subunit. (303 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1248 aa)
ENSPFOP00000003798Adenylate cyclase 2b (brain). (925 aa)
ENSPFOP00000003624Heparin-binding EGF-like growth factor a. (238 aa)
LOC103144528Heparin-binding EGF-like growth factor a. (236 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (876 aa)
ENSPFOP00000003322Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
ENSPFOP00000003238Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2055 aa)
LOC103144631Uncharacterized protein. (1292 aa)
LOC103138590Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1188 aa)
LOC103149084Uncharacterized protein. (390 aa)
LOC103151779Mitogen-activated protein kinase. (361 aa)
ENSPFOP00000002785Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (891 aa)
LOC103151778Mitogen-activated protein kinase. (362 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSPFOP00000002298Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (339 aa)
ENSPFOP00000002132ETS domain-containing protein. (504 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC103145765Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
LOC103152767Mitogen-activated protein kinase. (364 aa)
ENSPFOP00000001062Protein kinase domain-containing protein. (432 aa)
ENSPFOP00000000972Luteinizing hormone, beta polypeptide. (147 aa)
ADCY9Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1305 aa)
LOC103152501Tyrosine-protein kinase. (527 aa)
ENSPFOP00000000338Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
ENSPFOP00000023942Inositol 1,4,5-trisphosphate receptor, type 3. (2680 aa)
ENSPFOP00000024131GTP binding protein overexpressed in skeletal muscle. (309 aa)
ENSPFOP00000024266FERM domain-containing protein. (419 aa)
LOC103144355Mitogen-activated protein kinase. (360 aa)
ENSPFOP00000025375Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
ENSPFOP00000025965Uncharacterized protein. (174 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ENSPFOP00000027845Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2027 aa)
LOC103129836Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
CDC42Cell division cycle 42. (191 aa)
LOC103129281Protein kinase domain-containing protein. (238 aa)
LOC103129619Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (983 aa)
pla2g4aPhospholipase A2. (749 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (648 aa)
ENSPFOP00000030671Uncharacterized protein. (135 aa)
rradRas-related associated with diabetes. (309 aa)
ADCY9-2Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (772 aa)
ENSPFOP00000022348Raf-1 proto-oncogene, serine/threonine kinase a. (651 aa)
LOC103130823Uncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC103137045Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (324 aa)
ENSPFOP00000020202BZIP domain-containing protein; Belongs to the bZIP family. (325 aa)
calm2-3Calmodulin. (149 aa)
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
map2k4Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
ENSPFOP00000019002Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2063 aa)
LOC103142608Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (539 aa)
LOC103135363Uncharacterized protein. (359 aa)
LOC103136016G_PROTEIN_RECEP_F1_2 domain-containing protein. (426 aa)
ENSPFOP00000017922Uncharacterized protein. (96 aa)
ENSPFOP00000017888Mitogen-activated protein kinase kinase kinase 2. (498 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
REM1RRAD and GEM like GTPase 1. (307 aa)
LOC103133557Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (89 aa)
LOC103135989G_PROTEIN_RECEP_F1_2 domain-containing protein. (422 aa)
ENSPFOP00000017136Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (470 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1325 aa)
ENSPFOP00000017065Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1202 aa)
ENSPFOP00000016965Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
LOC103138402Matrix metallopeptidase 14b (membrane-inserted). (618 aa)
LOC103150485Mitogen-activated protein kinase. (368 aa)
pla2g4cPLA2c domain-containing protein. (581 aa)
mmp2Matrix metallopeptidase 2. (658 aa)
ENSPFOP00000016031Inositol 1,4,5-trisphosphate receptor, type 2. (2684 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC103135793Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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