(42 nodes) RNA Polymerase II Promoter Escape network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106953745	Cyclin H; Belongs to the cyclin family. (318 aa)
	LOC106953272	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (818 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (360 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	gtf2b	General transcription factor IIB. (318 aa)
	taf13	TATA-box binding protein associated factor 13. (125 aa)
	ENSPLAP00000005771	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (157 aa)
	taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (206 aa)
	LOC106957028	General transcription factor IIA, 1-like. (430 aa)
	LOC106943640	General transcription factor IIH, polypeptide 2. (275 aa)
	LOC106957710	TAFH domain-containing protein. (692 aa)
	tbp	TATA box binding protein. (304 aa)
	taf5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (782 aa)
	gtf2e1	General transcription factor IIE, polypeptide 1, alpha. (447 aa)
	ENSPLAP00000012054	Uncharacterized protein. (229 aa)
	LOC106959575	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (637 aa)
	taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
	taf2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1217 aa)
	ENSPLAP00000016416	TAF4 domain-containing protein. (283 aa)
	taf5l	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (601 aa)
	ercc3	Excision repair cross-complementation group 3. (771 aa)
	LOC106953350	Transcription initiation factor TFIID subunit. (1827 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	taf8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (306 aa)
	cdk20	Cyclin-dependent kinase 20. (261 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	LOC106938866	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (247 aa)
	TAF4	TATA-box binding protein associated factor 4. (856 aa)
	tbpl1	TBP-like 1. (143 aa)
	taf7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (368 aa)
	ENSPLAP00000024302	Uncharacterized protein. (284 aa)
	LOC106959106	Transcription initiation factor TFIID subunit 4-like. (921 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (419 aa)
	mnat1	MNAT1 component of CDK activating kinase. (296 aa)
	LOC106939932	Transcription initiation factor TFIID subunit 6-like. (637 aa)
	LOC106956922	General transcription factor IIA, 1. (393 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (300 aa)
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
	taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (941 aa)
	gtf2a2	General transcription factor IIA, 2. (119 aa)
	LOC106943114	General transcription factor IIH, polypeptide 2. (181 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000005771	ENSPLAP00000012054	ENSPLAP00000005771	ENSPLAP00000012054	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Uncharacterized protein.	0.974
ENSPLAP00000005771	ENSPLAP00000016416	ENSPLAP00000005771	ENSPLAP00000016416	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF4 domain-containing protein.	0.961
ENSPLAP00000005771	ENSPLAP00000024302	ENSPLAP00000005771	ENSPLAP00000024302	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Uncharacterized protein.	0.974
ENSPLAP00000005771	LOC106938866	ENSPLAP00000005771	ENSPLAP00000021256	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
ENSPLAP00000005771	LOC106939932	ENSPLAP00000005771	ENSPLAP00000025524	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Transcription initiation factor TFIID subunit 6-like.	0.991
ENSPLAP00000005771	LOC106943114	ENSPLAP00000005771	ENSPLAP00000031579	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIH, polypeptide 2.	0.874
ENSPLAP00000005771	LOC106943640	ENSPLAP00000005771	ENSPLAP00000007711	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIH, polypeptide 2.	0.874
ENSPLAP00000005771	LOC106953272	ENSPLAP00000005771	ENSPLAP00000001419	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.961
ENSPLAP00000005771	LOC106953350	ENSPLAP00000005771	ENSPLAP00000017972	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Transcription initiation factor TFIID subunit.	0.999
ENSPLAP00000005771	LOC106953745	ENSPLAP00000005771	ENSPLAP00000000607	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Cyclin H; Belongs to the cyclin family.	0.867
ENSPLAP00000005771	LOC106956922	ENSPLAP00000005771	ENSPLAP00000025597	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIA, 1.	0.961
ENSPLAP00000005771	LOC106957028	ENSPLAP00000005771	ENSPLAP00000007231	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIA, 1-like.	0.903
ENSPLAP00000005771	LOC106957710	ENSPLAP00000005771	ENSPLAP00000009314	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAFH domain-containing protein.	0.961
ENSPLAP00000005771	LOC106959106	ENSPLAP00000005771	ENSPLAP00000024347	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Transcription initiation factor TFIID subunit 4-like.	0.961
ENSPLAP00000005771	LOC106959575	ENSPLAP00000005771	ENSPLAP00000012633	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.991
ENSPLAP00000005771	TAF4	ENSPLAP00000005771	ENSPLAP00000021753	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TATA-box binding protein associated factor 4.	0.961
ENSPLAP00000005771	ccnh	ENSPLAP00000005771	ENSPLAP00000001502	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Cyclin H; Belongs to the cyclin family.	0.867
ENSPLAP00000005771	cdk20	ENSPLAP00000005771	ENSPLAP00000019780	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Cyclin-dependent kinase 20.	0.820
ENSPLAP00000005771	cdk7	ENSPLAP00000005771	ENSPLAP00000003235	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.820
ENSPLAP00000005771	ercc2	ENSPLAP00000005771	ENSPLAP00000020036	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Excision repair cross-complementation group 2.	0.911