54 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPLAP00000000066	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (136 aa)
	ENSPLAP00000001591	Zgc:136908; Belongs to the AAA ATPase family. (479 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (255 aa)
	ubac2	UBA domain containing 2. (397 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (826 aa)
	rnf145	Ring finger protein 145b. (704 aa)
	svip	Si:ch73-147o17.1. (80 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (748 aa)
	LOC106963812	Uncharacterized protein. (499 aa)
	pex6	Peroxisomal biogenesis factor 6. (1057 aa)
	plaa	Phospholipase A2-activating protein. (798 aa)
	LOC106935619	Si:dkey-24p1.6. (936 aa)
	LOC106964191	AAA domain-containing protein. (766 aa)
	SPATA5	Spermatogenesis associated 5. (904 aa)
	ENSPLAP00000011986	Uncharacterized protein. (75 aa)
	LOC106936332	YOD1 deubiquitinase. (300 aa)
	nploc4	NPL4 homolog, ubiquitin recognition factor. (630 aa)
	faf2	Fas associated factor family member 2. (445 aa)
	ufd1	Ubiquitin recognition factor in ER associated degradation 1. (311 aa)
	ubxn2a	UBX domain protein 2A. (235 aa)
	LOC106946836	Uncharacterized protein. (441 aa)
	derl2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	UBXN4	UBX domain protein 4. (516 aa)
	ube2g2	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	ENSPLAP00000017996	RING-type domain-containing protein. (68 aa)
	os9	OS9 endoplasmic reticulum lectin. (606 aa)
	ubxn1	UBX domain protein 1. (303 aa)
	aspscr1	ASPSCR1 tether for SLC2A4, UBX domain containing. (555 aa)
	ube4a	Ubiquitination factor E4A (UFD2 homolog, yeast). (1065 aa)
	nsfl1c	NSFL1 (p97) cofactor (p47). (374 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ubqln4	Ubiquilin 4. (583 aa)
	syvn1	Synovial apoptosis inhibitor 1, synoviolin. (635 aa)
	rad23a	RAD23 homolog A, nucleotide excision repair protein a. (365 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (680 aa)
	erlec1	Endoplasmic reticulum lectin 1. (460 aa)
	atad1	ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (411 aa)
	chfr	Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (627 aa)
	vcpip1	Valosin containing protein (p97)/p47 complex interacting protein 1. (1172 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)
	LOC106940083	Ubiquitin thioesterase OTU1. (300 aa)
	LOC106947714	Cytochrome c oxidase assembly factor 7. (230 aa)
	ube4b	Ubiquitination factor E4B, UFD2 homolog (S. cerevisiae). (1184 aa)
	LOC106951700	Ataxin 3. (322 aa)
	ubxn6	UBX domain protein 6. (438 aa)
	pex26	Uncharacterized protein. (297 aa)
	amfr	Autocrine motility factor receptor b. (622 aa)
	nvl	Nuclear VCP like. (815 aa)
	ngly1	N-glycanase 1. (634 aa)
	LOC106952049	Zmp:0000000662. (797 aa)
	ENSPLAP00000029134	UBX domain protein 10. (231 aa)
	pex1	Peroxisomal biogenesis factor 1. (1210 aa)
	ubxn7	UBX domain protein 7. (526 aa)
	ENSPLAP00000031476	UBX domain protein 11. (315 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000000066	ENSPLAP00000001591	ENSPLAP00000000066	ENSPLAP00000001591	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Zgc:136908; Belongs to the AAA ATPase family.	0.910
ENSPLAP00000000066	ENSPLAP00000011986	ENSPLAP00000000066	ENSPLAP00000011986	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.828
ENSPLAP00000000066	ENSPLAP00000017996	ENSPLAP00000000066	ENSPLAP00000017996	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	RING-type domain-containing protein.	0.845
ENSPLAP00000000066	ENSPLAP00000031476	ENSPLAP00000000066	ENSPLAP00000031476	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain protein 11.	0.677
ENSPLAP00000000066	LOC106935619	ENSPLAP00000000066	ENSPLAP00000010129	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Si:dkey-24p1.6.	0.964
ENSPLAP00000000066	LOC106946836	ENSPLAP00000000066	ENSPLAP00000014751	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.860
ENSPLAP00000000066	LOC106947714	ENSPLAP00000000066	ENSPLAP00000024138	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Cytochrome c oxidase assembly factor 7.	0.845
ENSPLAP00000000066	LOC106952049	ENSPLAP00000000066	ENSPLAP00000028914	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Zmp:0000000662.	0.833
ENSPLAP00000000066	LOC106963812	ENSPLAP00000000066	ENSPLAP00000008594	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.860
ENSPLAP00000000066	LOC106964191	ENSPLAP00000000066	ENSPLAP00000010621	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	AAA domain-containing protein.	0.711
ENSPLAP00000000066	SPATA5	ENSPLAP00000000066	ENSPLAP00000011814	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Spermatogenesis associated 5.	0.899
ENSPLAP00000000066	amfr	ENSPLAP00000000066	ENSPLAP00000027501	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor b.	0.961
ENSPLAP00000000066	atad1	ENSPLAP00000000066	ENSPLAP00000022219	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family.	0.708
ENSPLAP00000000066	aup1	ENSPLAP00000000066	ENSPLAP00000022813	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	AUP1 lipid droplet regulating VLDL assembly factor.	0.512
ENSPLAP00000000066	chfr	ENSPLAP00000000066	ENSPLAP00000022395	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase.	0.828
ENSPLAP00000000066	derl1	ENSPLAP00000000066	ENSPLAP00000004066	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.989
ENSPLAP00000000066	derl2	ENSPLAP00000000066	ENSPLAP00000014772	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.928
ENSPLAP00000000066	erlec1	ENSPLAP00000000066	ENSPLAP00000021676	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.962
ENSPLAP00000000066	faf1	ENSPLAP00000000066	ENSPLAP00000021567	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Fas (TNFRSF6) associated factor 1.	0.768
ENSPLAP00000000066	faf2	ENSPLAP00000000066	ENSPLAP00000013589	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Fas associated factor family member 2.	0.837