(5 nodes) IRE1-TRAF2-ASK1 complex network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	xbp1	X-box binding protein 1. (384 aa)
	ern1	Endoplasmic reticulum to nucleus signaling 1. (1060 aa)
	LOC106946130	Uncharacterized protein. (646 aa)
	LOC106940383	Uncharacterized protein. (230 aa)
	LOC106943519	Uncharacterized protein. (251 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106940383	LOC106946130	ENSPLAP00000020368	ENSPLAP00000014430	Uncharacterized protein.	Uncharacterized protein.	0.578
LOC106940383	ern1	ENSPLAP00000020368	ENSPLAP00000011603	Uncharacterized protein.	Endoplasmic reticulum to nucleus signaling 1.	0.882
LOC106940383	xbp1	ENSPLAP00000020368	ENSPLAP00000003088	Uncharacterized protein.	X-box binding protein 1.	0.928
LOC106943519	LOC106946130	ENSPLAP00000027493	ENSPLAP00000014430	Uncharacterized protein.	Uncharacterized protein.	0.560
LOC106943519	ern1	ENSPLAP00000027493	ENSPLAP00000011603	Uncharacterized protein.	Endoplasmic reticulum to nucleus signaling 1.	0.882
LOC106943519	xbp1	ENSPLAP00000027493	ENSPLAP00000003088	Uncharacterized protein.	X-box binding protein 1.	0.928
LOC106946130	LOC106940383	ENSPLAP00000014430	ENSPLAP00000020368	Uncharacterized protein.	Uncharacterized protein.	0.578
LOC106946130	LOC106943519	ENSPLAP00000014430	ENSPLAP00000027493	Uncharacterized protein.	Uncharacterized protein.	0.560
LOC106946130	ern1	ENSPLAP00000014430	ENSPLAP00000011603	Uncharacterized protein.	Endoplasmic reticulum to nucleus signaling 1.	0.883
LOC106946130	xbp1	ENSPLAP00000014430	ENSPLAP00000003088	Uncharacterized protein.	X-box binding protein 1.	0.928
ern1	LOC106940383	ENSPLAP00000011603	ENSPLAP00000020368	Endoplasmic reticulum to nucleus signaling 1.	Uncharacterized protein.	0.882
ern1	LOC106943519	ENSPLAP00000011603	ENSPLAP00000027493	Endoplasmic reticulum to nucleus signaling 1.	Uncharacterized protein.	0.882
ern1	LOC106946130	ENSPLAP00000011603	ENSPLAP00000014430	Endoplasmic reticulum to nucleus signaling 1.	Uncharacterized protein.	0.883
ern1	xbp1	ENSPLAP00000011603	ENSPLAP00000003088	Endoplasmic reticulum to nucleus signaling 1.	X-box binding protein 1.	0.978
xbp1	LOC106940383	ENSPLAP00000003088	ENSPLAP00000020368	X-box binding protein 1.	Uncharacterized protein.	0.928
xbp1	LOC106943519	ENSPLAP00000003088	ENSPLAP00000027493	X-box binding protein 1.	Uncharacterized protein.	0.928
xbp1	LOC106946130	ENSPLAP00000003088	ENSPLAP00000014430	X-box binding protein 1.	Uncharacterized protein.	0.928
xbp1	ern1	ENSPLAP00000003088	ENSPLAP00000011603	X-box binding protein 1.	Endoplasmic reticulum to nucleus signaling 1.	0.978