(6 nodes) RSK activation, and cAMP response element binding (CREB) protein network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106962538	Activating transcription factor 1. (311 aa)
	CRTC1	CREB regulated transcription coactivator 1b. (607 aa)
	LOC106964704	BZIP domain-containing protein. (206 aa)
	LOC106956531	Ribosomal protein S6 kinase. (735 aa)
	rps6ka3	Non-specific serine/threonine protein kinase. (714 aa)
	LOC106936744	Ribosomal protein S6 kinase. (720 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRTC1	LOC106936744	ENSPLAP00000018952	ENSPLAP00000030725	CREB regulated transcription coactivator 1b.	Ribosomal protein S6 kinase.	0.432
CRTC1	LOC106956531	ENSPLAP00000018952	ENSPLAP00000022874	CREB regulated transcription coactivator 1b.	Ribosomal protein S6 kinase.	0.432
CRTC1	LOC106962538	ENSPLAP00000018952	ENSPLAP00000008241	CREB regulated transcription coactivator 1b.	Activating transcription factor 1.	0.736
CRTC1	LOC106964704	ENSPLAP00000018952	ENSPLAP00000021224	CREB regulated transcription coactivator 1b.	BZIP domain-containing protein.	0.736
CRTC1	rps6ka3	ENSPLAP00000018952	ENSPLAP00000025082	CREB regulated transcription coactivator 1b.	Non-specific serine/threonine protein kinase.	0.432
LOC106936744	CRTC1	ENSPLAP00000030725	ENSPLAP00000018952	Ribosomal protein S6 kinase.	CREB regulated transcription coactivator 1b.	0.432
LOC106936744	LOC106956531	ENSPLAP00000030725	ENSPLAP00000022874	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.900
LOC106936744	LOC106962538	ENSPLAP00000030725	ENSPLAP00000008241	Ribosomal protein S6 kinase.	Activating transcription factor 1.	0.674
LOC106936744	LOC106964704	ENSPLAP00000030725	ENSPLAP00000021224	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.674
LOC106936744	rps6ka3	ENSPLAP00000030725	ENSPLAP00000025082	Ribosomal protein S6 kinase.	Non-specific serine/threonine protein kinase.	0.900
LOC106956531	CRTC1	ENSPLAP00000022874	ENSPLAP00000018952	Ribosomal protein S6 kinase.	CREB regulated transcription coactivator 1b.	0.432
LOC106956531	LOC106936744	ENSPLAP00000022874	ENSPLAP00000030725	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.900
LOC106956531	LOC106962538	ENSPLAP00000022874	ENSPLAP00000008241	Ribosomal protein S6 kinase.	Activating transcription factor 1.	0.674
LOC106956531	LOC106964704	ENSPLAP00000022874	ENSPLAP00000021224	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.674
LOC106956531	rps6ka3	ENSPLAP00000022874	ENSPLAP00000025082	Ribosomal protein S6 kinase.	Non-specific serine/threonine protein kinase.	0.900
LOC106962538	CRTC1	ENSPLAP00000008241	ENSPLAP00000018952	Activating transcription factor 1.	CREB regulated transcription coactivator 1b.	0.736
LOC106962538	LOC106936744	ENSPLAP00000008241	ENSPLAP00000030725	Activating transcription factor 1.	Ribosomal protein S6 kinase.	0.674
LOC106962538	LOC106956531	ENSPLAP00000008241	ENSPLAP00000022874	Activating transcription factor 1.	Ribosomal protein S6 kinase.	0.674
LOC106962538	rps6ka3	ENSPLAP00000008241	ENSPLAP00000025082	Activating transcription factor 1.	Non-specific serine/threonine protein kinase.	0.674
LOC106964704	CRTC1	ENSPLAP00000021224	ENSPLAP00000018952	BZIP domain-containing protein.	CREB regulated transcription coactivator 1b.	0.736