(45 nodes) Mixed, incl. Oligosaccharyltransferase complex, and Protein targeting to ER network (Poecilia latipinna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ncln	Nicalin. (530 aa)
	immp2l	Mitochondrial inner membrane protease subunit. (204 aa)
	ostc	Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (183 aa)
	spcs3	Signal peptidase complex subunit 3. (180 aa)
	LOC106937385	Nodal modulator. (1199 aa)
	tmem147	Transmembrane protein 147. (236 aa)
	LOC106945789	J domain-containing protein. (216 aa)
	ssr1	Signal sequence receptor, alpha. (292 aa)
	ddost	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (465 aa)
	ssr3	Signal sequence receptor, gamma. (185 aa)
	rpn2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (645 aa)
	ENSPLAP00000006151	Uncharacterized protein. (153 aa)
	dad1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
	ccdc47	Coiled-coil domain containing 47. (489 aa)
	ssr4	Signal sequence receptor, delta. (167 aa)
	sec62	SEC62 homolog, preprotein translocation factor. (416 aa)
	LOC106958153	Zgc:109965. (515 aa)
	ssr2	Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. (177 aa)
	mlec	Malectin. (286 aa)
	LOC106938528	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (394 aa)
	LOC106942657	Uncharacterized protein. (318 aa)
	stt3a	STT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
	LOC106957508	Uncharacterized protein. (702 aa)
	sec11a	Signal peptidase complex catalytic subunit SEC11. (179 aa)
	spcs2	Signal peptidase complex subunit 2. (201 aa)
	spcs1	Signal peptidase complex subunit 1. (102 aa)
	ENSPLAP00000013800	Oligosaccharyltransferase complex subunit 4 (non-catalytic). (53 aa)
	tmco1	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa)
	LOC106936854	Magnesium transporter 1. (328 aa)
	rab5if	RAB5 interacting factor. (127 aa)
	LOC106958414	Plug_translocon domain-containing protein. (476 aa)
	LOC106953257	Plug_translocon domain-containing protein. (476 aa)
	rpn1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (600 aa)
	tmem258	Transmembrane protein 258. (79 aa)
	LOC106934490	Uncharacterized protein. (285 aa)
	LOC106939419	Uncharacterized protein. (232 aa)
	tram2	Translocating chain-associated membrane protein; Belongs to the TRAM family. (369 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)
	stt3b	STT3 oligosaccharyltransferase complex catalytic subunit B. (812 aa)
	wdr83os	WD repeat domain 83 opposite strand. (104 aa)
	mogs	Mannosyl-oligosaccharide glucosidase. (845 aa)
	LOC106948895	Oxidative stress responsive kinase 1b. (535 aa)
	LOC106951992	Tumor suppressor candidate 3. (332 aa)
	sec61g	SEC61 translocon gamma subunit. (66 aa)
	LOC106934658	Oxidative stress responsive kinase 1a. (531 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000006151	LOC106937385	ENSPLAP00000006151	ENSPLAP00000003851	Uncharacterized protein.	Nodal modulator.	0.561
ENSPLAP00000006151	LOC106953257	ENSPLAP00000006151	ENSPLAP00000020068	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.711
ENSPLAP00000006151	LOC106958153	ENSPLAP00000006151	ENSPLAP00000009432	Uncharacterized protein.	Zgc:109965.	0.786
ENSPLAP00000006151	LOC106958414	ENSPLAP00000006151	ENSPLAP00000019167	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.711
ENSPLAP00000006151	ccdc47	ENSPLAP00000006151	ENSPLAP00000006997	Uncharacterized protein.	Coiled-coil domain containing 47.	0.887
ENSPLAP00000006151	ncln	ENSPLAP00000006151	ENSPLAP00000000239	Uncharacterized protein.	Nicalin.	0.891
ENSPLAP00000006151	rab5if	ENSPLAP00000006151	ENSPLAP00000018908	Uncharacterized protein.	RAB5 interacting factor.	0.674
ENSPLAP00000006151	sec61b	ENSPLAP00000006151	ENSPLAP00000024127	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.738
ENSPLAP00000006151	sec61g	ENSPLAP00000006151	ENSPLAP00000030144	Uncharacterized protein.	SEC61 translocon gamma subunit.	0.727
ENSPLAP00000006151	tmco1	ENSPLAP00000006151	ENSPLAP00000014011	Uncharacterized protein.	Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling.	0.888
ENSPLAP00000006151	wdr83os	ENSPLAP00000006151	ENSPLAP00000026652	Uncharacterized protein.	WD repeat domain 83 opposite strand.	0.757
ENSPLAP00000013800	LOC106934490	ENSPLAP00000013800	ENSPLAP00000021742	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Uncharacterized protein.	0.637
ENSPLAP00000013800	LOC106936854	ENSPLAP00000013800	ENSPLAP00000015550	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Magnesium transporter 1.	0.688
ENSPLAP00000013800	LOC106938528	ENSPLAP00000013800	ENSPLAP00000011567	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.826
ENSPLAP00000013800	LOC106939419	ENSPLAP00000013800	ENSPLAP00000021747	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Uncharacterized protein.	0.883
ENSPLAP00000013800	LOC106942657	ENSPLAP00000013800	ENSPLAP00000011620	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Uncharacterized protein.	0.688
ENSPLAP00000013800	LOC106951992	ENSPLAP00000013800	ENSPLAP00000029927	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Tumor suppressor candidate 3.	0.688
ENSPLAP00000013800	LOC106953257	ENSPLAP00000013800	ENSPLAP00000020068	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Plug_translocon domain-containing protein.	0.657
ENSPLAP00000013800	LOC106957508	ENSPLAP00000013800	ENSPLAP00000012702	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Uncharacterized protein.	0.883
ENSPLAP00000013800	LOC106958414	ENSPLAP00000013800	ENSPLAP00000019167	Oligosaccharyltransferase complex subunit 4 (non-catalytic).	Plug_translocon domain-containing protein.	0.657