52 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFNA5	Ephrin A5; Belongs to the ephrin family. (167 aa)
	nodal	Nodal-related 2. (376 aa)
	LOC106938894	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	bmp2	Bone morphogenetic protein 2b. (409 aa)
	lclat1	Lysocardiolipin acyltransferase 1. (390 aa)
	LOC106961202	MADS-box domain-containing protein. (471 aa)
	LOC106949849	Mesoderm posterior ba. (249 aa)
	ENSPLAP00000005822	Metalloendopeptidase. (958 aa)
	LOC106937271	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (347 aa)
	LOC106953622	T-box transcription factor Ta. (421 aa)
	lef1	Lymphoid enhancer-binding factor 1. (364 aa)
	LOC106956949	Lysine (K)-specific demethylase 6A, like. (1474 aa)
	wnt3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (530 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	msgn1	Mesogenin 1. (144 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (189 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	LOC106950057	Neurofibromin 2b (merlin). (617 aa)
	tbx19	Uncharacterized protein. (407 aa)
	LOC106959542	Southpaw. (408 aa)
	LOC106935492	Lysine (K)-specific demethylase 6B, a. (2100 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	exoc4	Exocyst complex component 4. (983 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	LOC106937270	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
	ENSPLAP00000022901	BHLH domain-containing protein. (113 aa)
	LOC106949253	Lysine (K)-specific demethylase 6B, b. (1735 aa)
	kdm6a	Lysine (K)-specific demethylase 6A. (1447 aa)
	LOC106951145	Uncharacterized protein; Belongs to the integrin alpha chain family. (915 aa)
	tbxt	T-box transcription factor Tb. (436 aa)
	nf2	Neurofibromin 2a (merlin). (591 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	armc5	Armadillo repeat containing 5. (1130 aa)
	bmp1	Metalloendopeptidase. (970 aa)
	ENSPLAP00000017769	Integrin, alpha 3b; Belongs to the integrin alpha chain family. (846 aa)
	LOC106941352	Uncharacterized protein. (347 aa)
	srf	Serum response factor b. (601 aa)
	foxh1	Forkhead box H1. (507 aa)
	ENSPLAP00000016289	Uncharacterized protein. (91 aa)
	LOC106960842	Ventral homeobox. (242 aa)
	LOC106941507	Uncharacterized protein. (445 aa)
	taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
	LOC106948963	T-cell acute lymphocytic leukemia 1. (396 aa)
	itgb4	Integrin beta. (1722 aa)
	LOC106950119	Ephrin-A5a; Belongs to the ephrin family. (229 aa)
	apela	Apelin receptor early endogenous ligand. (54 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	ENSPLAP00000011711	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	LOC106962469	Protein O-fucosyltransferase 2. (410 aa)
	ENSPLAP00000010230	Protein O-fucosyltransferase 2. (168 aa)
	dkk1	TNFR-Cys domain-containing protein. (251 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFNA5	LOC106959966	ENSPLAP00000012778	ENSPLAP00000019635	Ephrin A5; Belongs to the ephrin family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.400
EFNA5	bmpr2	ENSPLAP00000012778	ENSPLAP00000027360	Ephrin A5; Belongs to the ephrin family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.400
ENSPLAP00000005822	bmp2	ENSPLAP00000005822	ENSPLAP00000003581	Metalloendopeptidase.	Bone morphogenetic protein 2b.	0.466
ENSPLAP00000011711	LOC106937270	ENSPLAP00000011711	ENSPLAP00000023282	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.610
ENSPLAP00000011711	LOC106937271	ENSPLAP00000011711	ENSPLAP00000006365	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.610
ENSPLAP00000011711	LOC106939913	ENSPLAP00000011711	ENSPLAP00000028818	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	FZ domain-containing protein.	0.950
ENSPLAP00000011711	LOC106953622	ENSPLAP00000011711	ENSPLAP00000006799	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor Ta.	0.551
ENSPLAP00000011711	dkk1	ENSPLAP00000011711	ENSPLAP00000009481	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	TNFR-Cys domain-containing protein.	0.820
ENSPLAP00000011711	lef1	ENSPLAP00000011711	ENSPLAP00000008638	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Lymphoid enhancer-binding factor 1.	0.638
ENSPLAP00000011711	sfrp2	ENSPLAP00000011711	ENSPLAP00000031613	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2.	0.947
ENSPLAP00000011711	tbxt	ENSPLAP00000011711	ENSPLAP00000019875	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor Tb.	0.561
ENSPLAP00000017769	LOC106951145	ENSPLAP00000017769	ENSPLAP00000020351	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Uncharacterized protein; Belongs to the integrin alpha chain family.	0.936
ENSPLAP00000017769	itgb4	ENSPLAP00000017769	ENSPLAP00000013578	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Integrin beta.	0.918
LOC106935492	LOC106938894	ENSPLAP00000027536	ENSPLAP00000002910	Lysine (K)-specific demethylase 6B, a.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.411
LOC106935492	LOC106949253	ENSPLAP00000027536	ENSPLAP00000022699	Lysine (K)-specific demethylase 6B, a.	Lysine (K)-specific demethylase 6B, b.	0.696
LOC106935492	LOC106956949	ENSPLAP00000027536	ENSPLAP00000008797	Lysine (K)-specific demethylase 6B, a.	Lysine (K)-specific demethylase 6A, like.	0.696
LOC106935492	gpi	ENSPLAP00000027536	ENSPLAP00000009180	Lysine (K)-specific demethylase 6B, a.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.411
LOC106935492	kdm6a	ENSPLAP00000027536	ENSPLAP00000022069	Lysine (K)-specific demethylase 6B, a.	Lysine (K)-specific demethylase 6A.	0.696
LOC106937270	ENSPLAP00000011711	ENSPLAP00000023282	ENSPLAP00000011711	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.610
LOC106937270	LOC106939913	ENSPLAP00000023282	ENSPLAP00000028818	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	FZ domain-containing protein.	0.939