39 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (466 aa)
	ENSPLAP00000026331	Vasoactive intestinal peptide. (180 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
	sp1	Sp1 transcription factor. (656 aa)
	ENSPLAP00000029046	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (455 aa)
	sirt6	Sirtuin 6. (351 aa)
	LOC106939157	Bone morphogenetic protein 16. (477 aa)
	LOC106956726	JunE proto-oncogene, AP-1 transcription factor subunit. (323 aa)
	agtr1	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	ecm1	Uncharacterized protein. (483 aa)
	LOC106945885	Uncharacterized protein. (1387 aa)
	prok1	Prokineticin 1. (102 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (561 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	ENSPLAP00000004479	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (176 aa)
	sirt1	Sirtuin 1. (677 aa)
	LOC106941138	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	jun	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
	LOC106959096	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	aggf1	Angiogenic factor with G patch and FHA domains 1. (752 aa)
	ENSPLAP00000008402	Fibronectin type-III domain-containing protein. (196 aa)
	adam17	ADAM metallopeptidase domain 17b. (841 aa)
	mydgf	Myeloid-derived growth factor. (191 aa)
	ENSPLAP00000000306	Uncharacterized protein. (581 aa)
	LOC106962201	Secretogranin II (chromogranin C), b. (585 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (208 aa)
	LOC106941476	Uncharacterized protein. (285 aa)
	ENSPLAP00000013913	Fibroblast growth factor binding protein 1b. (226 aa)
	apela	Apelin receptor early endogenous ligand. (54 aa)
	LOC106954181	ADAM metallopeptidase domain 17a. (859 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1294 aa)
	il10	Interleukin 10. (181 aa)
	LOC106953738	LRRCT domain-containing protein. (343 aa)
	LOC106959917	Insulin-like growth factor 2b. (235 aa)
	ENSPLAP00000002053	Raptor_N domain-containing protein. (101 aa)
	ENSPLAP00000002210	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (158 aa)
	nf1	Neurofibromin 1b. (2795 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000002053	sirt1	ENSPLAP00000002053	ENSPLAP00000005614	Raptor_N domain-containing protein.	Sirtuin 1.	0.470
ENSPLAP00000002053	sp1	ENSPLAP00000002053	ENSPLAP00000028305	Raptor_N domain-containing protein.	Sp1 transcription factor.	0.403
ENSPLAP00000002210	ENSPLAP00000004479	ENSPLAP00000002210	ENSPLAP00000004479	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.855
ENSPLAP00000002210	ENSPLAP00000029046	ENSPLAP00000002210	ENSPLAP00000029046	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.723
ENSPLAP00000002210	pdgfb	ENSPLAP00000002210	ENSPLAP00000020496	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.723
ENSPLAP00000004479	ENSPLAP00000002210	ENSPLAP00000004479	ENSPLAP00000002210	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.855
ENSPLAP00000004479	ENSPLAP00000029046	ENSPLAP00000004479	ENSPLAP00000029046	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.731
ENSPLAP00000004479	pdgfb	ENSPLAP00000004479	ENSPLAP00000020496	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.731
ENSPLAP00000004479	vegfa	ENSPLAP00000004479	ENSPLAP00000008541	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.794
ENSPLAP00000013913	LOC106939157	ENSPLAP00000013913	ENSPLAP00000029728	Fibroblast growth factor binding protein 1b.	Bone morphogenetic protein 16.	0.412
ENSPLAP00000013913	bmp4	ENSPLAP00000013913	ENSPLAP00000019124	Fibroblast growth factor binding protein 1b.	Bone morphogenetic protein 4.	0.412
ENSPLAP00000013913	fgf7	ENSPLAP00000013913	ENSPLAP00000028103	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.860
ENSPLAP00000029046	ENSPLAP00000002210	ENSPLAP00000029046	ENSPLAP00000002210	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.723
ENSPLAP00000029046	ENSPLAP00000004479	ENSPLAP00000029046	ENSPLAP00000004479	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.731
ENSPLAP00000029046	LOC106959917	ENSPLAP00000029046	ENSPLAP00000001936	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Insulin-like growth factor 2b.	0.610
ENSPLAP00000029046	vegfa	ENSPLAP00000029046	ENSPLAP00000008541	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.734
LOC106939157	ENSPLAP00000013913	ENSPLAP00000029728	ENSPLAP00000013913	Bone morphogenetic protein 16.	Fibroblast growth factor binding protein 1b.	0.412
LOC106939157	LOC106959966	ENSPLAP00000029728	ENSPLAP00000019635	Bone morphogenetic protein 16.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.965
LOC106939157	bmp4	ENSPLAP00000029728	ENSPLAP00000019124	Bone morphogenetic protein 16.	Bone morphogenetic protein 4.	0.888
LOC106939157	bmpr2	ENSPLAP00000029728	ENSPLAP00000027360	Bone morphogenetic protein 16.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.973