30 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (747 aa)
	LOC106937460	Mothers against decapentaplegic homolog. (510 aa)
	tbx3	T-box transcription factor 3a. (703 aa)
	LOC106944326	Mothers against decapentaplegic homolog. (503 aa)
	LOC106939239	Mothers against decapentaplegic homolog. (534 aa)
	jun	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
	LOC106962756	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (489 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	LOC106956726	JunE proto-oncogene, AP-1 transcription factor subunit. (323 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	ENSPLAP00000011303	Zinc finger protein, FOG family member 2a. (1026 aa)
	ilk	Integrin linked kinase. (452 aa)
	ENSPLAP00000011500	Neuropilin 2a. (540 aa)
	LOC106954227	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	ENSPLAP00000011951	Uncharacterized protein. (202 aa)
	ENSPLAP00000012514	CUB domain-containing protein. (164 aa)
	nkx2-5	NK2 homeobox 5. (318 aa)
	LOC106955479	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	LOC106947313	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)
	LOC106946879	Endothelin 1. (183 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	ILK	Integrin linked kinase. (452 aa)
	LOC106953315	Neuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	dhrs3	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
	gja5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
	LOC106948550	Neuropilin; Belongs to the neuropilin family. (858 aa)
	LOC106952668	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (515 aa)
	ENSPLAP00000024818	Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (386 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000011303	ENSPLAP00000011951	ENSPLAP00000011303	ENSPLAP00000011951	Zinc finger protein, FOG family member 2a.	Uncharacterized protein.	0.672
ENSPLAP00000011500	ENSPLAP00000012514	ENSPLAP00000011500	ENSPLAP00000012514	Neuropilin 2a.	CUB domain-containing protein.	0.532
ENSPLAP00000011500	sema3c	ENSPLAP00000011500	ENSPLAP00000020709	Neuropilin 2a.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family.	0.513
ENSPLAP00000011951	ENSPLAP00000011303	ENSPLAP00000011951	ENSPLAP00000011303	Uncharacterized protein.	Zinc finger protein, FOG family member 2a.	0.672
ENSPLAP00000012514	ENSPLAP00000011500	ENSPLAP00000012514	ENSPLAP00000011500	CUB domain-containing protein.	Neuropilin 2a.	0.532
ENSPLAP00000012514	sema3c	ENSPLAP00000012514	ENSPLAP00000020709	CUB domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family.	0.513
ENSPLAP00000024818	LOC106946879	ENSPLAP00000024818	ENSPLAP00000028390	Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.589
ILK	ilk	ENSPLAP00000024838	ENSPLAP00000011483	Integrin linked kinase.	Integrin linked kinase.	0.904
LOC106937460	LOC106939239	ENSPLAP00000019866	ENSPLAP00000006841	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.786
LOC106937460	LOC106944326	ENSPLAP00000019866	ENSPLAP00000003577	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.796
LOC106937460	LOC106954227	ENSPLAP00000019866	ENSPLAP00000011505	Mothers against decapentaplegic homolog.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.783
LOC106937460	LOC106956726	ENSPLAP00000019866	ENSPLAP00000029854	Mothers against decapentaplegic homolog.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.516
LOC106937460	LOC106959966	ENSPLAP00000019866	ENSPLAP00000019635	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.776
LOC106937460	TGFBR2	ENSPLAP00000019866	ENSPLAP00000016741	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.783
LOC106937460	bmpr2	ENSPLAP00000019866	ENSPLAP00000027360	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.776
LOC106937460	jun	ENSPLAP00000019866	ENSPLAP00000007533	Mothers against decapentaplegic homolog.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.516
LOC106937460	nkx2-5	ENSPLAP00000019866	ENSPLAP00000013697	Mothers against decapentaplegic homolog.	NK2 homeobox 5.	0.417
LOC106939239	LOC106937460	ENSPLAP00000006841	ENSPLAP00000019866	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.786
LOC106939239	LOC106944326	ENSPLAP00000006841	ENSPLAP00000003577	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.904
LOC106939239	LOC106954227	ENSPLAP00000006841	ENSPLAP00000011505	Mothers against decapentaplegic homolog.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.783