57 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	mstn	Myostatin b. (375 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1075 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (189 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	LOC106934858	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
	LOC106947313	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)
	LOC106954217	Troponin I type 1b (skeletal, slow). (186 aa)
	ccn1	Cellular communication network factor 1. (380 aa)
	LOC106959732	Mothers against decapentaplegic homolog. (332 aa)
	ENSPLAP00000024818	Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	LOC106941180	Uncharacterized protein. (479 aa)
	greb1	Growth regulating estrogen receptor binding 1. (1789 aa)
	LOC106944537	T-box transcription factor 5a. (517 aa)
	ENSPLAP00000020762	Troponin C type 1b (slow). (167 aa)
	LOC106947507	Transforming growth factor beta; Belongs to the TGF-beta family. (373 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (747 aa)
	hectd1	HECT domain containing 1. (2487 aa)
	LOC106937460	Mothers against decapentaplegic homolog. (510 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	LOC106946650	Troponin I type 1a (skeletal, slow). (187 aa)
	LOC106959997	PR domain containing 1a, with ZNF domain. (759 aa)
	nprl3	NPR3-like, GATOR1 complex subunit. (595 aa)
	LOC106953315	Neuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	trip11	Thyroid hormone receptor interactor 11. (1953 aa)
	LOC106952668	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (515 aa)
	gja5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
	LOC106963602	PR domain containing 1b, with ZNF domain. (630 aa)
	LOC106955479	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	nkx2-5	NK2 homeobox 5. (318 aa)
	LOC106938369	Aryl hydrocarbon receptor nuclear translocator. (810 aa)
	ENSPLAP00000013169	Uncharacterized protein. (99 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	ENSPLAP00000011951	Uncharacterized protein. (202 aa)
	LOC106954227	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	ENSPLAP00000011303	Zinc finger protein, FOG family member 2a. (1026 aa)
	sav1	Salvador family WW domain containing protein 1. (396 aa)
	smad6	Mothers against decapentaplegic homolog. (490 aa)
	dctn5	Dynactin 5. (182 aa)
	hace1	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (897 aa)
	ptcd2	Pentatricopeptide repeat domain 2. (383 aa)
	LOC106939239	Mothers against decapentaplegic homolog. (534 aa)
	LOC106957040	Uncharacterized protein. (783 aa)
	sall4	Spalt-like transcription factor 4. (1081 aa)
	TNNC1	Troponin C type 1a (slow). (163 aa)
	cpe	Carboxypeptidase E. (456 aa)
	LOC106949849	Mesoderm posterior ba. (249 aa)
	smad7	Mothers against decapentaplegic homolog. (364 aa)
	ENSPLAP00000004039	PWWP domain-containing protein. (171 aa)
	ENSPLAP00000004009	Nuclear receptor binding SET domain protein 2. (487 aa)
	LOC106944326	Mothers against decapentaplegic homolog. (503 aa)
	LOC106940303	Aryl-hydrocarbon receptor nuclear translocator 2. (381 aa)
	LOC106953195	Uncharacterized protein. (649 aa)
	tmem65	Transmembrane protein 65. (240 aa)
	TMEM65	Transmembrane protein 65. (212 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000004009	LOC106941180	ENSPLAP00000004009	ENSPLAP00000022678	Nuclear receptor binding SET domain protein 2.	Uncharacterized protein.	0.447
ENSPLAP00000004009	LOC106957040	ENSPLAP00000004009	ENSPLAP00000006839	Nuclear receptor binding SET domain protein 2.	Uncharacterized protein.	0.447
ENSPLAP00000004009	LOC106959997	ENSPLAP00000004009	ENSPLAP00000019406	Nuclear receptor binding SET domain protein 2.	PR domain containing 1a, with ZNF domain.	0.447
ENSPLAP00000004009	LOC106963602	ENSPLAP00000004009	ENSPLAP00000014721	Nuclear receptor binding SET domain protein 2.	PR domain containing 1b, with ZNF domain.	0.447
ENSPLAP00000004009	PTK7	ENSPLAP00000004009	ENSPLAP00000029954	Nuclear receptor binding SET domain protein 2.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.425
ENSPLAP00000004009	nkx2-5	ENSPLAP00000004009	ENSPLAP00000013697	Nuclear receptor binding SET domain protein 2.	NK2 homeobox 5.	0.573
ENSPLAP00000004009	sall4	ENSPLAP00000004009	ENSPLAP00000006604	Nuclear receptor binding SET domain protein 2.	Spalt-like transcription factor 4.	0.506
ENSPLAP00000004039	LOC106941180	ENSPLAP00000004039	ENSPLAP00000022678	PWWP domain-containing protein.	Uncharacterized protein.	0.447
ENSPLAP00000004039	LOC106957040	ENSPLAP00000004039	ENSPLAP00000006839	PWWP domain-containing protein.	Uncharacterized protein.	0.447
ENSPLAP00000004039	LOC106959997	ENSPLAP00000004039	ENSPLAP00000019406	PWWP domain-containing protein.	PR domain containing 1a, with ZNF domain.	0.447
ENSPLAP00000004039	LOC106963602	ENSPLAP00000004039	ENSPLAP00000014721	PWWP domain-containing protein.	PR domain containing 1b, with ZNF domain.	0.447
ENSPLAP00000004039	PTK7	ENSPLAP00000004039	ENSPLAP00000029954	PWWP domain-containing protein.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.425
ENSPLAP00000004039	nkx2-5	ENSPLAP00000004039	ENSPLAP00000013697	PWWP domain-containing protein.	NK2 homeobox 5.	0.573
ENSPLAP00000004039	sall4	ENSPLAP00000004039	ENSPLAP00000006604	PWWP domain-containing protein.	Spalt-like transcription factor 4.	0.506
ENSPLAP00000011303	ENSPLAP00000011951	ENSPLAP00000011303	ENSPLAP00000011951	Zinc finger protein, FOG family member 2a.	Uncharacterized protein.	0.672
ENSPLAP00000011951	ENSPLAP00000011303	ENSPLAP00000011951	ENSPLAP00000011303	Uncharacterized protein.	Zinc finger protein, FOG family member 2a.	0.672
ENSPLAP00000013169	LOC106938369	ENSPLAP00000013169	ENSPLAP00000013639	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.525
ENSPLAP00000013169	LOC106940303	ENSPLAP00000013169	ENSPLAP00000002930	Uncharacterized protein.	Aryl-hydrocarbon receptor nuclear translocator 2.	0.525
ENSPLAP00000020762	LOC106946650	ENSPLAP00000020762	ENSPLAP00000019627	Troponin C type 1b (slow).	Troponin I type 1a (skeletal, slow).	0.955
ENSPLAP00000020762	LOC106954217	ENSPLAP00000020762	ENSPLAP00000026763	Troponin C type 1b (slow).	Troponin I type 1b (skeletal, slow).	0.951