89 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106954657	Deltex 2, E3 ubiquitin ligase. (564 aa)
	adam17	ADAM metallopeptidase domain 17b. (841 aa)
	LOC106953946	Hairy-related 5. (196 aa)
	LOC106958437	Deltex 4, E3 ubiquitin ligase a. (611 aa)
	LOC106950609	RING-type domain-containing protein. (269 aa)
	LOC106950607	RING-type domain-containing protein. (285 aa)
	LOC106950610	RING-type domain-containing protein. (198 aa)
	susd5	Sushi domain containing 5. (528 aa)
	LOC106955286	Si:ch1073-396h14.1. (659 aa)
	ENSPLAP00000000734	EGF-like domain-containing protein. (91 aa)
	LOC106958371	Hes related family bHLH transcription factor with YRPW motif like. (316 aa)
	LOC106947336	Glutamate receptor interacting protein 2b. (960 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (587 aa)
	LOC106940390	Nuclear receptor interacting protein 2. (271 aa)
	LOC106963330	Notch receptor 1a. (2447 aa)
	ENSPLAP00000002808	MamL-1 domain-containing protein. (132 aa)
	gmds	GDP-mannose 4,6-dehydratase. (371 aa)
	gsx2	GS homeobox 2. (241 aa)
	pln	Si:ch211-270g19.5. (129 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (826 aa)
	traf7	TNF receptor-associated factor 7. (690 aa)
	got1	Aspartate aminotransferase. (410 aa)
	atoh7	Atonal bHLH transcription factor 7. (144 aa)
	LOC106960655	Pep_M12B_propep domain-containing protein. (129 aa)
	LOC106937192	RING-type domain-containing protein. (412 aa)
	snai2	Snail family zinc finger 2. (261 aa)
	LOC106938615	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa)
	lfng	Beta-1,3-N-acetylglucosaminyltransferase. (370 aa)
	LOC106936426	Beta-1,3-N-acetylglucosaminyltransferase. (387 aa)
	LOC106935602	Uncharacterized protein. (982 aa)
	nr0b2	Nuclear receptor subfamily 0, group B, member 2a. (260 aa)
	jag2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1248 aa)
	chac1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (202 aa)
	LOC106954227	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	LOC106948196	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (635 aa)
	rbpj	Recombination signal binding protein for immunoglobulin kappa J region. (468 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (459 aa)
	nrip2	Nuclear receptor interacting protein 2. (206 aa)
	LOC106954181	ADAM metallopeptidase domain 17a. (859 aa)
	LOC106940831	Uncharacterized protein. (777 aa)
	maml3	Mastermind-like transcriptional coactivator 3. (1159 aa)
	dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (712 aa)
	LOC106950874	RING-type domain-containing protein. (205 aa)
	LOC106963661	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (196 aa)
	nle1	Notchless homolog 1 (Drosophila). (478 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (340 aa)
	LOC106942401	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (424 aa)
	pofut1	Protein O-fucosyltransferase 1. (397 aa)
	ENSPLAP00000015949	Mindbomb E3 ubiquitin protein ligase 1. (1039 aa)
	LOC106952699	Recombination signal binding protein for immunoglobulin kappa J region a. (488 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
	LOC106936770	Mindbomb E3 ubiquitin protein ligase 2. (693 aa)
	tspear	Thrombospondin-type laminin G domain and EAR repeats b. (549 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1240 aa)
	LOC106937462	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (737 aa)
	ENSPLAP00000019040	Disintegrin domain-containing protein. (339 aa)
	LOC106953952	Hairy-related 11. (276 aa)
	ENSPLAP00000019193	MNNL domain-containing protein. (126 aa)
	pkd2	Polycystic kidney disease 2. (892 aa)
	ENSPLAP00000019276	RING-type domain-containing protein. (248 aa)
	ENSPLAP00000019292	RING-type domain-containing protein. (207 aa)
	LOC106947507	Transforming growth factor beta; Belongs to the TGF-beta family. (373 aa)
	ift74	Intraflagellar transport 74. (602 aa)
	psenen	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	bap1	Ubiquitin carboxyl-terminal hydrolase. (727 aa)
	TMEM100	Transmembrane protein 100. (134 aa)
	hey1	Hes-related family bHLH transcription factor with YRPW motif 1. (371 aa)
	LOC106947837	Nuclear receptor subfamily 1, group H, member 5. (477 aa)
	ENSPLAP00000022509	Mindbomb E3 ubiquitin protein ligase 2. (428 aa)
	ncstn	Ncstrn_small domain-containing protein. (604 aa)
	maml2	Uncharacterized protein. (756 aa)
	LOC106942802	RING-type domain-containing protein. (255 aa)
	LOC106954293	Notch receptor 1b. (2443 aa)
	DTX1	Deltex E3 ubiquitin ligase 1. (642 aa)
	LOC106958140	ADAM metallopeptidase domain 10b. (781 aa)
	LOC106934908	Glutamate receptor interacting protein 2a. (949 aa)
	LOC106936403	Methyl CpG binding protein 2. (997 aa)
	fsd1	Fibronectin type III and SPRY domain containing 1. (493 aa)
	LOC106957497	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (694 aa)
	LOC106950872	Zgc:66440. (368 aa)
	timp4	TIMP metallopeptidase inhibitor 4, tandem duplicate 2. (210 aa)
	LOC106957491	Thrombospondin-type laminin G domain and EAR repeats a. (636 aa)
	hes3	Uncharacterized protein. (248 aa)
	GALNT11	Polypeptide N-acetylgalactosaminyltransferase. (570 aa)
	LOC106951976	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (476 aa)
	LOC106935386	APH1B gamma secretase subunit. (258 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	nrarp	NOTCH regulated ankyrin repeat protein a. (112 aa)
	GOT1	Aspartate aminotransferase. (410 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DTX1	ENSPLAP00000000734	ENSPLAP00000025417	ENSPLAP00000000734	Deltex E3 ubiquitin ligase 1.	EGF-like domain-containing protein.	0.432
DTX1	ENSPLAP00000019193	ENSPLAP00000025417	ENSPLAP00000019193	Deltex E3 ubiquitin ligase 1.	MNNL domain-containing protein.	0.447
DTX1	ENSPLAP00000019276	ENSPLAP00000025417	ENSPLAP00000019276	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.527
DTX1	ENSPLAP00000019292	ENSPLAP00000025417	ENSPLAP00000019292	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.537
DTX1	ENSPLAP00000022509	ENSPLAP00000025417	ENSPLAP00000022509	Deltex E3 ubiquitin ligase 1.	Mindbomb E3 ubiquitin protein ligase 2.	0.481
DTX1	LOC106935602	ENSPLAP00000025417	ENSPLAP00000010341	Deltex E3 ubiquitin ligase 1.	Uncharacterized protein.	0.447
DTX1	LOC106936770	ENSPLAP00000025417	ENSPLAP00000017273	Deltex E3 ubiquitin ligase 1.	Mindbomb E3 ubiquitin protein ligase 2.	0.481
DTX1	LOC106937192	ENSPLAP00000025417	ENSPLAP00000007531	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.527
DTX1	LOC106937462	ENSPLAP00000025417	ENSPLAP00000018919	Deltex E3 ubiquitin ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.432
DTX1	LOC106938615	ENSPLAP00000025417	ENSPLAP00000009676	Deltex E3 ubiquitin ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.432
DTX1	LOC106942802	ENSPLAP00000025417	ENSPLAP00000025029	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.676
DTX1	LOC106948196	ENSPLAP00000025417	ENSPLAP00000012041	Deltex E3 ubiquitin ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.432
DTX1	LOC106950607	ENSPLAP00000025417	ENSPLAP00000000439	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.664
DTX1	LOC106950609	ENSPLAP00000025417	ENSPLAP00000000436	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.542
DTX1	LOC106950610	ENSPLAP00000025417	ENSPLAP00000000440	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.536
DTX1	LOC106950872	ENSPLAP00000025417	ENSPLAP00000027635	Deltex E3 ubiquitin ligase 1.	Zgc:66440.	0.688
DTX1	LOC106950874	ENSPLAP00000025417	ENSPLAP00000012975	Deltex E3 ubiquitin ligase 1.	RING-type domain-containing protein.	0.536
DTX1	LOC106954293	ENSPLAP00000025417	ENSPLAP00000025395	Deltex E3 ubiquitin ligase 1.	Notch receptor 1b.	0.945
DTX1	LOC106957497	ENSPLAP00000025417	ENSPLAP00000026478	Deltex E3 ubiquitin ligase 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.432
DTX1	LOC106963330	ENSPLAP00000025417	ENSPLAP00000001986	Deltex E3 ubiquitin ligase 1.	Notch receptor 1a.	0.945