119 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106965199	Si:ch211-11n16.2. (655 aa)
	map1lc3c	Microtubule-associated protein 1 light chain 3 gamma. (128 aa)
	ENSPLAP00000031455	Uncharacterized protein. (540 aa)
	ENSPLAP00000031447	Protein kinase domain-containing protein. (364 aa)
	seh1l	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (383 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (876 aa)
	cbwd1	COBW domain containing. (368 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1652 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (627 aa)
	gcn1	GCN1 activator of EIF2AK4. (2634 aa)
	LOC106960824	Sestrin 2. (558 aa)
	wdr45b	WD repeat domain 45B. (344 aa)
	JMY-2	Junction mediating and regulatory protein, p53 cofactor. (820 aa)
	LOC106934749	Protein kinase domain-containing protein. (92 aa)
	ENSPLAP00000028649	Uncharacterized protein. (166 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1181 aa)
	ENSPLAP00000027489	Protein kinase domain-containing protein. (92 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	LOC106949058	Protein phosphatase, Mg2+/Mn2+ dependent, 1Db. (591 aa)
	ZFYVE1	Uncharacterized protein. (783 aa)
	clec16a	C-type lectin domain containing 16A. (937 aa)
	wdr45	WD repeat domain 45. (363 aa)
	LOC106949141	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (544 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
	LOC106947675	Uncharacterized protein. (363 aa)
	LOC106962851	Death associated protein 1b. (116 aa)
	rrp8	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (548 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (564 aa)
	ENSPLAP00000024381	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (214 aa)
	LOC106949811	Si:zfos-80g12.1. (444 aa)
	gabarap	GABA(A) receptor-associated protein b. (122 aa)
	LOC106937241	Uncharacterized protein. (184 aa)
	zfyve1	Zinc finger, FYVE domain containing 1. (790 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9. (561 aa)
	LOC106953096	Si:ch211-125a15.1. (452 aa)
	LOC106952592	Non-specific serine/threonine protein kinase. (557 aa)
	ttc5	Tetratricopeptide repeat domain 5. (439 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1068 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	nprl3	NPR3-like, GATOR1 complex subunit. (595 aa)
	LOC106940492	E3 ubiquitin-protein ligase RNF152-like. (174 aa)
	sesn1	Sestrin 1. (545 aa)
	WIPI1	WD repeat domain, phosphoinositide interacting 1. (444 aa)
	LOC106945327	Uncharacterized protein. (639 aa)
	map1lc3a	Microtubule-associated protein 1 light chain 3 alpha. (121 aa)
	nprl2	NPR2 like, GATOR1 complex subunit. (381 aa)
	rragc	Ras-related GTP binding Ca. (382 aa)
	wdr24	WD repeat domain 24. (783 aa)
	ENSPLAP00000017168	Uncharacterized protein. (105 aa)
	ENSPLAP00000017163	Uncharacterized protein. (122 aa)
	LOC106942262	Ring finger protein 152. (174 aa)
	atf3	Activating transcription factor 3. (259 aa)
	LOC106937543	Uncharacterized protein. (677 aa)
	ENSPLAP00000016894	CBM21 domain-containing protein. (292 aa)
	bmt2	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (387 aa)
	LOC106941359	Mechanistic target of rapamycin kinase. (927 aa)
	ENSPLAP00000016678	WD repeat domain 59. (701 aa)
	LOC106960832	NUAK family, SNF1-like kinase, 1b. (661 aa)
	lamp2	Lysosomal-associated membrane protein 2. (420 aa)
	WHAMM	WASP homolog associated with actin, golgi membranes and microtubules. (782 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1104 aa)
	gabarapl2	GABA(A) receptor-associated protein like 2. (56 aa)
	LOC106940689	Salt-inducible kinase 1. (806 aa)
	LOC106940692	Uncharacterized protein. (654 aa)
	atg7	ATG7 autophagy related 7 homolog (S. cerevisiae). (728 aa)
	LOC106939808	Si:ch211-22d5.2; Belongs to the protein kinase superfamily. (435 aa)
	impact	Impact RWD domain protein. (323 aa)
	pick1	Protein interacting with prkca 1. (409 aa)
	LOC106953474	Cytoplasmic polyadenylation element binding protein 4a. (763 aa)
	ENSPLAP00000013433	UBA domain-containing protein. (448 aa)
	LOC106936283	Si:dkey-16p21.7. (727 aa)
	LOC106959558	Protein kinase domain-containing protein. (760 aa)
	lars1	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family. (1184 aa)
	fbxo22	F-box protein 22. (387 aa)
	LOC106951552	Si:dkey-206d17.12. (404 aa)
	LOC106952126	WD repeat domain, phosphoinositide interacting 1. (451 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2312 aa)
	prkag1	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (329 aa)
	pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1325 aa)
	map1lc3b	Microtubule-associated protein 1 light chain 3 beta. (134 aa)
	kptn	Kaptin (actin binding protein). (440 aa)
	itfg2	Integrin alpha FG-GAP repeat containing 2. (433 aa)
	dap	Death-associated protein. (105 aa)
	LOC106938980	Xenotropic and polytropic retrovirus receptor 1b. (582 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1294 aa)
	prkag3	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (340 aa)
	nuak2	NUAK family, SNF1-like kinase, 2. (606 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	sik2	Salt-inducible kinase 2b. (933 aa)
	JMY	Junction mediating and regulatory protein, p53 cofactor. (894 aa)
	flcn	Folliculin. (554 aa)
	LOC106958432	Transcription factor EB. (330 aa)
	ENSPLAP00000009100	Uncharacterized protein. (274 aa)
	becn1	Beclin 1, autophagy related. (448 aa)
	brsk1	Protein kinase domain-containing protein. (848 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	gas6	Uncharacterized protein. (650 aa)
	LOC106949189	Si:ch211-117c9.1. (696 aa)
	ppm1d	Protein phosphatase, Mg2+/Mn2+ dependent, 1Da. (552 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	ENSPLAP00000006441	Reverse transcriptase domain-containing protein. (323 aa)
	sirt1	Sirtuin 1. (677 aa)
	wipi2	WD repeat domain, phosphoinositide interacting 2. (427 aa)
	LOC106938764	Si:ch211-153j24.3. (382 aa)
	LOC106949313	GABA type A receptor associated protein like 2. (117 aa)
	LOC106955731	Ras-related GTP binding A. (315 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	ENSPLAP00000003531	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
	LOC106963230	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (319 aa)
	xbp1	X-box binding protein 1. (384 aa)
	ENSPLAP00000002770	Basic helix-loop-helix family, member a15. (192 aa)
	tbl2	Transducin (beta)-like 2. (441 aa)
	LOC106936789	Activating transcription factor 4a. (424 aa)
	ENSPLAP00000002053	Raptor_N domain-containing protein. (101 aa)
	fnip1	Folliculin interacting protein 1. (1220 aa)
	ENSPLAP00000000519	Reverse transcriptase domain-containing protein. (225 aa)
	ENSPLAP00000000507	Uncharacterized protein. (81 aa)
	mios	Missing oocyte, meiosis regulator, homolog (Drosophila). (867 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	ENSPLAP00000002053	ENSPLAP00000030376	ENSPLAP00000002053	Eukaryotic translation initiation factor 2 alpha kinase 4.	Raptor_N domain-containing protein.	0.829
EIF2AK4	ENSPLAP00000024381	ENSPLAP00000030376	ENSPLAP00000024381	Eukaryotic translation initiation factor 2 alpha kinase 4.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.709
EIF2AK4	ENSPLAP00000031455	ENSPLAP00000030376	ENSPLAP00000031455	Eukaryotic translation initiation factor 2 alpha kinase 4.	Uncharacterized protein.	0.709
EIF2AK4	LOC106936789	ENSPLAP00000030376	ENSPLAP00000002219	Eukaryotic translation initiation factor 2 alpha kinase 4.	Activating transcription factor 4a.	0.615
EIF2AK4	LOC106941359	ENSPLAP00000030376	ENSPLAP00000016783	Eukaryotic translation initiation factor 2 alpha kinase 4.	Mechanistic target of rapamycin kinase.	0.929
EIF2AK4	LOC106945327	ENSPLAP00000030376	ENSPLAP00000018431	Eukaryotic translation initiation factor 2 alpha kinase 4.	Uncharacterized protein.	0.709
EIF2AK4	LOC106955731	ENSPLAP00000030376	ENSPLAP00000004770	Eukaryotic translation initiation factor 2 alpha kinase 4.	Ras-related GTP binding A.	0.546
EIF2AK4	atg5	ENSPLAP00000030376	ENSPLAP00000007884	Eukaryotic translation initiation factor 2 alpha kinase 4.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.406
EIF2AK4	eif2ak3	ENSPLAP00000030376	ENSPLAP00000015768	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.942
EIF2AK4	eif2s1	ENSPLAP00000030376	ENSPLAP00000003800	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.996
EIF2AK4	gcn1	ENSPLAP00000030376	ENSPLAP00000030064	Eukaryotic translation initiation factor 2 alpha kinase 4.	GCN1 activator of EIF2AK4.	0.882
EIF2AK4	hspa5	ENSPLAP00000030376	ENSPLAP00000019917	Eukaryotic translation initiation factor 2 alpha kinase 4.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.513
EIF2AK4	impact	ENSPLAP00000030376	ENSPLAP00000015088	Eukaryotic translation initiation factor 2 alpha kinase 4.	Impact RWD domain protein.	0.554
EIF2AK4	lars1	ENSPLAP00000030376	ENSPLAP00000013047	Eukaryotic translation initiation factor 2 alpha kinase 4.	Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.692
EIF2AK4	nfe2l2	ENSPLAP00000030376	ENSPLAP00000006584	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2-like 2a.	0.958
EIF2AK4	rptor	ENSPLAP00000030376	ENSPLAP00000011506	Eukaryotic translation initiation factor 2 alpha kinase 4.	Regulatory associated protein of MTOR, complex 1.	0.829
EIF2AK4	sirt1	ENSPLAP00000030376	ENSPLAP00000005614	Eukaryotic translation initiation factor 2 alpha kinase 4.	Sirtuin 1.	0.434
EIF2AK4	ttc5	ENSPLAP00000030376	ENSPLAP00000020016	Eukaryotic translation initiation factor 2 alpha kinase 4.	Tetratricopeptide repeat domain 5.	0.494
EIF2AK4	xbp1	ENSPLAP00000030376	ENSPLAP00000003088	Eukaryotic translation initiation factor 2 alpha kinase 4.	X-box binding protein 1.	0.581
ENSPLAP00000002053	EIF2AK4	ENSPLAP00000002053	ENSPLAP00000030376	Raptor_N domain-containing protein.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.829