106 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	grem2	Gremlin 2, DAN family BMP antagonist a. (192 aa)
	LOC106950373	Uncharacterized protein. (1325 aa)
	LOC106941082	Huluwa. (217 aa)
	gsc	Goosecoid. (237 aa)
	GSC	Goosecoid. (225 aa)
	LOC106937271	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (347 aa)
	LOC106943016	SET domain-containing protein. (456 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (405 aa)
	ENSPLAP00000005822	Metalloendopeptidase. (958 aa)
	LOC106949244	Vestigial-like family member 2a. (296 aa)
	LOC106953020	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
	LOC106959222	Uncharacterized protein. (883 aa)
	GID8	GID complex subunit 8 homolog. (229 aa)
	gsx2	GS homeobox 2. (241 aa)
	LOC106959281	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
	bmp2	Bone morphogenetic protein 2b. (409 aa)
	LOC106946465	SIX homeobox 7. (260 aa)
	en1	Homeobox protein engrailed-like. (284 aa)
	ENSPLAP00000002455	Si:ch211-207e14.4. (407 aa)
	hhip	Hedgehog interacting protein. (697 aa)
	smad1	Mothers against decapentaplegic homolog. (467 aa)
	LOC106942026	Uncharacterized protein. (191 aa)
	LOC106964084	DZF domain-containing protein. (131 aa)
	LOC106959992	Forkhead box G1d. (344 aa)
	ENSPLAP00000000351	Zinc finger RNA binding protein. (477 aa)
	ddit4	DNA-damage-inducible transcript 4. (225 aa)
	LOC106958579	RE1-silencing transcription factor. (907 aa)
	LOC106939722	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (234 aa)
	fkbp8	Peptidylprolyl isomerase. (396 aa)
	LOC106936011	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (297 aa)
	MAX	MYC associated factor X. (150 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
	gdf6	Growth differentiation factor 6a. (418 aa)
	six6	SIX homeobox 6a. (245 aa)
	gli1	GLI family zinc finger 1. (1485 aa)
	tctn1	DUF1619 domain-containing protein. (524 aa)
	LOC106946879	Endothelin 1. (183 aa)
	acvr1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (691 aa)
	LOC106956259	DUF1619 domain-containing protein. (614 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	ttc21b	Tetratricopeptide repeat domain 21B. (1317 aa)
	rfx4	Regulatory factor X, 4. (688 aa)
	LOC106957085	Axin 2 (conductin, axil). (838 aa)
	LOC106938520	Zinc finger RNA binding protein 2. (1027 aa)
	LOC106934858	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
	hhex	Homeobox domain-containing protein. (302 aa)
	mapk10	Mitogen-activated protein kinase. (360 aa)
	LOC106954890	GID complex subunit 8 homolog b (S. cerevisiae). (228 aa)
	chrd	Chordin; Belongs to the chordin family. (933 aa)
	LOC106960571	Uncharacterized protein. (269 aa)
	fbxl15	F-box and leucine-rich repeat protein 15. (292 aa)
	bmpr1b	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
	LOC106940086	Homeobox protein engrailed-like. (254 aa)
	LOC106936562	GLI family zinc finger 3. (1066 aa)
	LOC106939272	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (322 aa)
	LOC106937270	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
	max	Myc associated factor X. (160 aa)
	il17rd	Interleukin 17 receptor D. (779 aa)
	LOC106957970	Mothers against decapentaplegic homolog. (475 aa)
	ift46	Uncharacterized protein. (335 aa)
	ENSPLAP00000020867	SIX homeobox 3a. (259 aa)
	foxn4	Forkhead box N4. (502 aa)
	LOC106934576	Forkhead box G1a. (346 aa)
	rnf220	Ring finger protein 220a. (384 aa)
	RNF220	RNF220 domain-containing protein. (268 aa)
	LOC106942166	Lysine methyltransferase 5Ab. (336 aa)
	LOC106948662	SIX homeobox 3b. (277 aa)
	pkd2	Polycystic kidney disease 2. (892 aa)
	gdf5	Growth differentiation factor 5. (486 aa)
	wdr19	WD repeat domain 19. (1334 aa)
	bmp1	Metalloendopeptidase. (970 aa)
	LOC106948175	POU domain protein. (476 aa)
	LOC106949389	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
	LOC106956667	Notochord homeobox. (241 aa)
	ppp4c	Serine/threonine-protein phosphatase. (311 aa)
	GREM1	Gremlin. (182 aa)
	axin1	Axin 1. (795 aa)
	foxh1	Forkhead box H1. (507 aa)
	LOC106960842	Ventral homeobox. (242 aa)
	aida	Axin interactor, dorsalization associated. (305 aa)
	ENSPLAP00000015949	Mindbomb E3 ubiquitin protein ligase 1. (1039 aa)
	LOC106944787	Mitogen-activated protein kinase. (460 aa)
	LOC106942497	N-lysine methyltransferase SETD8-like. (456 aa)
	LOC106954091	GLI family zinc finger 2a. (1446 aa)
	ENSPLAP00000013757	Ring finger protein 220b. (211 aa)
	LOC106957989	Uncharacterized protein. (529 aa)
	LHX3	LIM homeobox 3. (421 aa)
	AXIN2	Axin 2. (794 aa)
	LOC106962379	Mitogen-activated protein kinase 8b. (402 aa)
	kmt5a	Lysine methyltransferase 5Aa. (331 aa)
	ENSPLAP00000011711	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	ift52	Intraflagellar transport 52 homolog (Chlamydomonas). (435 aa)
	b4galt5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5. (382 aa)
	ENSPLAP00000010753	LIM zinc-binding domain-containing protein. (57 aa)
	lhx1	LIM homeobox 1a. (316 aa)
	ENSPLAP00000010696	Gremlin 1a, DAN family BMP antagonist. (159 aa)
	LOC106940886	DNA damage-inducible transcript 4 protein-like. (225 aa)
	LOC106945036	Fibroblast growth factor receptor. (831 aa)
	lhx4	LIM homeobox 4. (389 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
	lrrc6	Leucine rich repeat containing 6. (397 aa)
	fst	Follistatin a. (349 aa)
	yap1	Yes-associated protein 1. (433 aa)
	wnt3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	LOC106955590	Noggin; Belongs to the noggin family. (211 aa)
	LOC106945133	Fork-head domain-containing protein. (393 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	ENSPLAP00000011711	ENSPLAP00000012430	ENSPLAP00000011711	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.738
AXIN2	LOC106936011	ENSPLAP00000012430	ENSPLAP00000031502	Axin 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.431
AXIN2	LOC106937270	ENSPLAP00000012430	ENSPLAP00000023282	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.646
AXIN2	LOC106937271	ENSPLAP00000012430	ENSPLAP00000006365	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.646
AXIN2	LOC106949389	ENSPLAP00000012430	ENSPLAP00000017931	Axin 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.431
AXIN2	LOC106957085	ENSPLAP00000012430	ENSPLAP00000026802	Axin 2.	Axin 2 (conductin, axil).	0.787
AXIN2	LOC106959222	ENSPLAP00000012430	ENSPLAP00000004707	Axin 2.	Uncharacterized protein.	0.908
AXIN2	axin1	ENSPLAP00000012430	ENSPLAP00000016337	Axin 2.	Axin 1.	0.908
AXIN2	ctnnb1	ENSPLAP00000012430	ENSPLAP00000027240	Axin 2.	Catenin (cadherin-associated protein), beta 1.	0.983
AXIN2	wnt3	ENSPLAP00000012430	ENSPLAP00000008811	Axin 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.603
AXIN2	yap1	ENSPLAP00000012430	ENSPLAP00000008955	Axin 2.	Yes-associated protein 1.	0.728
ENSPLAP00000000351	LOC106942026	ENSPLAP00000000351	ENSPLAP00000001651	Zinc finger RNA binding protein.	Uncharacterized protein.	0.936
ENSPLAP00000000351	LOC106964084	ENSPLAP00000000351	ENSPLAP00000001078	Zinc finger RNA binding protein.	DZF domain-containing protein.	0.895
ENSPLAP00000005822	bmp2	ENSPLAP00000005822	ENSPLAP00000003581	Metalloendopeptidase.	Bone morphogenetic protein 2b.	0.466
ENSPLAP00000005822	chrd	ENSPLAP00000005822	ENSPLAP00000025317	Metalloendopeptidase.	Chordin; Belongs to the chordin family.	0.903
ENSPLAP00000005822	yap1	ENSPLAP00000005822	ENSPLAP00000008955	Metalloendopeptidase.	Yes-associated protein 1.	0.420
ENSPLAP00000010696	GREM1	ENSPLAP00000010696	ENSPLAP00000016954	Gremlin 1a, DAN family BMP antagonist.	Gremlin.	0.898
ENSPLAP00000010696	LOC106946879	ENSPLAP00000010696	ENSPLAP00000028390	Gremlin 1a, DAN family BMP antagonist.	Endothelin 1.	0.410
ENSPLAP00000010696	bmp2	ENSPLAP00000010696	ENSPLAP00000003581	Gremlin 1a, DAN family BMP antagonist.	Bone morphogenetic protein 2b.	0.901
ENSPLAP00000010696	chrd	ENSPLAP00000010696	ENSPLAP00000025317	Gremlin 1a, DAN family BMP antagonist.	Chordin; Belongs to the chordin family.	0.422