53 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106952593	Phospholipid phosphatase 3. (302 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (924 aa)
	mst1r	Macrophage stimulating 1 receptor b. (1365 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (627 aa)
	ENSPLAP00000030099	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
	LOC106949456	Macrophage stimulating 1 receptor a. (1374 aa)
	ENSPLAP00000029046	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (455 aa)
	sp1	Sp1 transcription factor. (656 aa)
	aamp	Angio-associated, migratory cell protein. (418 aa)
	LOC106949014	SAM and SH3 domain containing 1a. (1352 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	LOC106944955	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1344 aa)
	LOC106962807	CD40 molecule, TNF receptor superfamily member 5. (313 aa)
	hspb1	Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (200 aa)
	srpx2	Sushi-repeat containing protein X-linked 2. (420 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (462 aa)
	LOC106934453	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
	LOC106945885	Uncharacterized protein. (1387 aa)
	LOC106947507	Transforming growth factor beta; Belongs to the TGF-beta family. (373 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (561 aa)
	LOC106939608	Uncharacterized protein. (909 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	lgmn	Legumain. (437 aa)
	atp5f1b	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
	LOC106963543	Ras and Rab interactor 2. (1121 aa)
	LOC106955382	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (141 aa)
	ENSPLAP00000013913	Fibroblast growth factor binding protein 1b. (226 aa)
	LOC106951552	Si:dkey-206d17.12. (404 aa)
	LOC106954181	ADAM metallopeptidase domain 17a. (859 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	LOC106937107	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)
	pik3cg	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1121 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (530 aa)
	LOC106962867	SAM and SH3 domain containing 1b. (874 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (208 aa)
	bcas3	BCAS3 microtubule associated cell migration factor. (821 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	ATP5F1A	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (548 aa)
	LOC106937281	Basigin. (272 aa)
	sirt1	Sirtuin 1. (677 aa)
	LOC106956587	SAM domain-containing protein. (409 aa)
	tsta3	Tissue specific transplantation antigen P35B. (315 aa)
	LOC106938894	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	LOC106963298	Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (199 aa)
	LOC106959917	Insulin-like growth factor 2b. (235 aa)
	LOC106950541	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
	LOC106953245	GATA binding protein 2a. (456 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	LOC106958419	Uncharacterized protein. (461 aa)
	adam17	ADAM metallopeptidase domain 17b. (841 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5F1A	LOC106938894	ENSPLAP00000006491	ENSPLAP00000002910	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.779
ATP5F1A	LOC106944955	ENSPLAP00000006491	ENSPLAP00000026991	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.978
ATP5F1A	atp5f1b	ENSPLAP00000006491	ENSPLAP00000017841	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ATP5F1A	gpi	ENSPLAP00000006491	ENSPLAP00000009180	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.779
ENSPLAP00000013913	ENSPLAP00000030099	ENSPLAP00000013913	ENSPLAP00000030099	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.687
ENSPLAP00000013913	LOC106937107	ENSPLAP00000013913	ENSPLAP00000009947	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.687
ENSPLAP00000013913	LOC106950541	ENSPLAP00000013913	ENSPLAP00000001812	Fibroblast growth factor binding protein 1b.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.828
ENSPLAP00000013913	LOC106955382	ENSPLAP00000013913	ENSPLAP00000016140	Fibroblast growth factor binding protein 1b.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.828
ENSPLAP00000013913	fgf16	ENSPLAP00000013913	ENSPLAP00000000359	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.610
ENSPLAP00000013913	fgf2	ENSPLAP00000013913	ENSPLAP00000011793	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.520
ENSPLAP00000029046	LOC106949456	ENSPLAP00000029046	ENSPLAP00000030032	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Macrophage stimulating 1 receptor a.	0.839
ENSPLAP00000029046	LOC106959917	ENSPLAP00000029046	ENSPLAP00000001936	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Insulin-like growth factor 2b.	0.610
ENSPLAP00000029046	fgf2	ENSPLAP00000029046	ENSPLAP00000011793	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.469
ENSPLAP00000029046	met	ENSPLAP00000029046	ENSPLAP00000026056	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	MET proto-oncogene, receptor tyrosine kinase.	0.839
ENSPLAP00000029046	mst1r	ENSPLAP00000029046	ENSPLAP00000030460	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Macrophage stimulating 1 receptor b.	0.839
ENSPLAP00000029046	nrp1	ENSPLAP00000029046	ENSPLAP00000030551	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Neuropilin; Belongs to the neuropilin family.	0.475
ENSPLAP00000029046	vegfa	ENSPLAP00000029046	ENSPLAP00000008541	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.734
ENSPLAP00000030099	ENSPLAP00000013913	ENSPLAP00000030099	ENSPLAP00000013913	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor binding protein 1b.	0.687
ENSPLAP00000030099	LOC106947507	ENSPLAP00000030099	ENSPLAP00000020747	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.400
ENSPLAP00000030099	LOC106949456	ENSPLAP00000030099	ENSPLAP00000030032	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Macrophage stimulating 1 receptor a.	0.638