(13 nodes) Protein kinase A signaling network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prkacb	Uncharacterized protein. (300 aa)
	LOC106945099	Myomesin 1b. (1434 aa)
	mroh1	Maestro heat-like repeat family member 1. (1649 aa)
	LOC106955479	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	LOC106941471	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	ENSPLAP00000017458	Uncharacterized protein. (684 aa)
	LOC106952668	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (515 aa)
	prkaca	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (333 aa)
	LOC106946593	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
	LOC106938025	Uncharacterized protein. (200 aa)
	RAB13	RAB13, member RAS oncogene family. (213 aa)
	LOC106946879	Endothelin 1. (183 aa)
	LOC106955448	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106938025	LOC106941471	ENSPLAP00000020335	ENSPLAP00000015353	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.867
LOC106938025	LOC106946593	ENSPLAP00000020335	ENSPLAP00000020103	Uncharacterized protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.871
LOC106938025	LOC106955448	ENSPLAP00000020335	ENSPLAP00000028959	Uncharacterized protein.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.896
LOC106938025	prkaca	ENSPLAP00000020335	ENSPLAP00000018989	Uncharacterized protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.857
LOC106941471	LOC106938025	ENSPLAP00000015353	ENSPLAP00000020335	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.867
LOC106941471	LOC106946593	ENSPLAP00000015353	ENSPLAP00000020103	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.891
LOC106941471	LOC106955448	ENSPLAP00000015353	ENSPLAP00000028959	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.896
LOC106941471	RAB13	ENSPLAP00000015353	ENSPLAP00000021789	Uncharacterized protein; Belongs to the protein kinase superfamily.	RAB13, member RAS oncogene family.	0.867
LOC106941471	prkaca	ENSPLAP00000015353	ENSPLAP00000018989	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.891
LOC106946593	LOC106938025	ENSPLAP00000020103	ENSPLAP00000020335	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.871
LOC106946593	LOC106941471	ENSPLAP00000020103	ENSPLAP00000015353	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.891
LOC106946593	LOC106955448	ENSPLAP00000020103	ENSPLAP00000028959	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	0.897
LOC106946593	RAB13	ENSPLAP00000020103	ENSPLAP00000021789	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	RAB13, member RAS oncogene family.	0.871
LOC106946593	prkaca	ENSPLAP00000020103	ENSPLAP00000018989	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.	0.891
LOC106946593	prkacb	ENSPLAP00000020103	ENSPLAP00000005677	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.872
LOC106946879	LOC106952668	ENSPLAP00000028390	ENSPLAP00000018035	Endothelin 1.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.996
LOC106946879	LOC106955479	ENSPLAP00000028390	ENSPLAP00000014086	Endothelin 1.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.998
LOC106952668	LOC106946879	ENSPLAP00000018035	ENSPLAP00000028390	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.996
LOC106952668	LOC106955479	ENSPLAP00000018035	ENSPLAP00000014086	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.905
LOC106955448	LOC106938025	ENSPLAP00000028959	ENSPLAP00000020335	Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.896