38 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mettl16	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (551 aa)
	prpf8	Pre-mRNA processing factor 8. (2323 aa)
	LOC106942356	Gem-associated protein 5-like. (1479 aa)
	LOC106942475	Gem (nuclear organelle) associated protein 5. (1479 aa)
	LOC106958867	Leucine rich repeat containing 51. (185 aa)
	LOC106941577	Si:ch1073-157b13.1. (550 aa)
	LOC106964943	Cyclin T1; Belongs to the cyclin family. (684 aa)
	lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (143 aa)
	ENSPLAP00000027105	Uncharacterized protein. (183 aa)
	ccnt2	Cyclin T2; Belongs to the cyclin family. (693 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	snu13	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
	ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
	snrnp70	Small nuclear ribonucleoprotein 70 (U1). (466 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	lrmda	Leucine rich melanocyte differentiation associated. (192 aa)
	rbm41	RNA binding motif protein 41. (422 aa)
	snrpa1	Small nuclear ribonucleoprotein polypeptide A. (258 aa)
	LOC106943238	WD_REPEATS_REGION domain-containing protein. (1186 aa)
	snrpa	Small nuclear ribonucleoprotein polypeptide A. (273 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (304 aa)
	toe1	Target of EGR1, exonuclease. (506 aa)
	ENSPLAP00000014309	Cyclin N-terminal domain-containing protein. (188 aa)
	lsm10	LSM10, U7 small nuclear RNA associated. (131 aa)
	LOC106960930	Methylphosphate capping enzyme. (712 aa)
	sf3b3	Splicing factor 3b, subunit 3. (1217 aa)
	prpf31	PRP31 pre-mRNA processing factor 31 homolog (yeast). (508 aa)
	snrpc	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (147 aa)
	larp7	La ribonucleoprotein domain family, member 7. (558 aa)
	rnpc3	RNA-binding region (RNP1, RRM) containing 3. (507 aa)
	prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast). (339 aa)
	rbmx	RNA binding motif protein X-linked. (383 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (971 aa)
	ro60	Ro60, Y RNA binding protein. (537 aa)
	rbm22	RNA binding motif protein 22. (426 aa)
	snrpb2	Small nuclear ribonucleoprotein polypeptide B2. (220 aa)
	sart3	Spliceosome associated factor 3, U4/U6 recycling protein. (945 aa)
	LOC106953289	HEXIM P-TEFb complex subunit 1. (367 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000014309	LOC106941577	ENSPLAP00000014309	ENSPLAP00000028237	Cyclin N-terminal domain-containing protein.	Si:ch1073-157b13.1.	0.473
ENSPLAP00000014309	LOC106953289	ENSPLAP00000014309	ENSPLAP00000001308	Cyclin N-terminal domain-containing protein.	HEXIM P-TEFb complex subunit 1.	0.779
ENSPLAP00000014309	LOC106960930	ENSPLAP00000014309	ENSPLAP00000011319	Cyclin N-terminal domain-containing protein.	Methylphosphate capping enzyme.	0.489
ENSPLAP00000014309	larp7	ENSPLAP00000014309	ENSPLAP00000009430	Cyclin N-terminal domain-containing protein.	La ribonucleoprotein domain family, member 7.	0.792
ENSPLAP00000014309	ncbp2	ENSPLAP00000014309	ENSPLAP00000030930	Cyclin N-terminal domain-containing protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.633
ENSPLAP00000014309	rbmx	ENSPLAP00000014309	ENSPLAP00000008003	Cyclin N-terminal domain-containing protein.	RNA binding motif protein X-linked.	0.467
ENSPLAP00000027105	eftud2	ENSPLAP00000027105	ENSPLAP00000007888	Uncharacterized protein.	Elongation factor Tu GTP binding domain containing 2.	0.882
ENSPLAP00000027105	larp7	ENSPLAP00000027105	ENSPLAP00000009430	Uncharacterized protein.	La ribonucleoprotein domain family, member 7.	0.415
ENSPLAP00000027105	lsm10	ENSPLAP00000027105	ENSPLAP00000013093	Uncharacterized protein.	LSM10, U7 small nuclear RNA associated.	0.860
ENSPLAP00000027105	lsm3	ENSPLAP00000027105	ENSPLAP00000019977	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.723
ENSPLAP00000027105	lsm4	ENSPLAP00000027105	ENSPLAP00000027560	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.826
ENSPLAP00000027105	ncbp2	ENSPLAP00000027105	ENSPLAP00000030930	Uncharacterized protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.828
ENSPLAP00000027105	prpf31	ENSPLAP00000027105	ENSPLAP00000010384	Uncharacterized protein.	PRP31 pre-mRNA processing factor 31 homolog (yeast).	0.826
ENSPLAP00000027105	prpf4	ENSPLAP00000027105	ENSPLAP00000008717	Uncharacterized protein.	PRP4 pre-mRNA processing factor 4 homolog (yeast).	0.661
ENSPLAP00000027105	prpf8	ENSPLAP00000027105	ENSPLAP00000029997	Uncharacterized protein.	Pre-mRNA processing factor 8.	0.868
ENSPLAP00000027105	rbm22	ENSPLAP00000027105	ENSPLAP00000004610	Uncharacterized protein.	RNA binding motif protein 22.	0.637
ENSPLAP00000027105	rbm41	ENSPLAP00000027105	ENSPLAP00000018190	Uncharacterized protein.	RNA binding motif protein 41.	0.870
ENSPLAP00000027105	rbmx	ENSPLAP00000027105	ENSPLAP00000008003	Uncharacterized protein.	RNA binding motif protein X-linked.	0.415
ENSPLAP00000027105	rnpc3	ENSPLAP00000027105	ENSPLAP00000009298	Uncharacterized protein.	RNA-binding region (RNP1, RRM) containing 3.	0.870
ENSPLAP00000027105	sf3b3	ENSPLAP00000027105	ENSPLAP00000011218	Uncharacterized protein.	Splicing factor 3b, subunit 3.	0.944