135 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPLAP00000030078	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (692 aa)
	tomm70	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (578 aa)
	LOC106942687	Sema domain-containing protein; Belongs to the semaphorin family. (489 aa)
	CCN3	Cellular communication network factor 3. (412 aa)
	LOC106934884	SH3-domain binding protein 4. (871 aa)
	LOC106956347	Interferon-related developmental regulator 2. (436 aa)
	LOC106950548	Inositol hexakisphosphate kinase 2-like. (461 aa)
	LOC106965115	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H; Belongs to the semaphorin family. (766 aa)
	st7	Suppression of tumorigenicity 7. (511 aa)
	bmp10	Bone morphogenetic protein 10. (488 aa)
	LOC106937682	Slit homolog 1b (Drosophila). (1382 aa)
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (312 aa)
	LOC106960571	Uncharacterized protein. (269 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa)
	LOC106941702	Unc-51 like autophagy activating kinase 1. (939 aa)
	LOC106940045	Sema domain-containing protein; Belongs to the semaphorin family. (507 aa)
	LOC106954993	Sema domain-containing protein. (913 aa)
	fhl1	Four and a half LIM domains 1a. (297 aa)
	wt1	WT1 transcription factor b. (422 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	LOC106940152	Si:dkey-177p2.6. (259 aa)
	prdm11	PR domain containing 11. (1033 aa)
	LOC106941245	Uncharacterized protein; Belongs to the semaphorin family. (852 aa)
	ENSPLAP00000021539	Uncharacterized protein. (358 aa)
	ENSPLAP00000021271	SCP domain-containing protein; Belongs to the CRISP family. (293 aa)
	ENSPLAP00000021211	Sema domain-containing protein; Belongs to the semaphorin family. (261 aa)
	LOC106947507	Transforming growth factor beta; Belongs to the TGF-beta family. (373 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (747 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
	cdkn2aip	CDKN2A interacting protein. (317 aa)
	LOC106953256	Kinase; Belongs to the inositol phosphokinase (IPK) family. (502 aa)
	sh3bp4	SH3-domain binding protein 4a. (960 aa)
	LOC106937460	Mothers against decapentaplegic homolog. (510 aa)
	ENSPLAP00000019695	Reticulon 4 receptor. (470 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	sema6d	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like; Belongs to the semaphorin family. (1037 aa)
	dcun1d3	DCN1-like protein. (320 aa)
	rb1	Retinoblastoma 1. (913 aa)
	sema4b	Uncharacterized protein; Belongs to the semaphorin family. (838 aa)
	epha4	Eph receptor A4, like. (1000 aa)
	ulk1	Unc-51 like autophagy activating kinase 1a. (892 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (396 aa)
	LOC106958413	Kinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
	slit2	Slit homolog 2 (Drosophila). (1416 aa)
	LOC106934605	Sema domain-containing protein; Belongs to the semaphorin family. (1170 aa)
	LOC106954457	Testis specific protein Y-linked; Belongs to the nucleosome assembly protein (NAP) family. (561 aa)
	rerg	RAS like estrogen regulated growth inhibitor. (191 aa)
	ryk	Receptor like tyrosine kinase. (634 aa)
	MINAR1	Membrane integral NOTCH2 associated receptor 1. (815 aa)
	ENSPLAP00000031114	FCP1 homology domain-containing protein. (324 aa)
	LOC106936703	Transforming growth factor beta; Belongs to the TGF-beta family. (399 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1644 aa)
	LOC106954400	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga; Belongs to the semaphorin family. (744 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	sertad3	SERTA domain-containing protein. (213 aa)
	LOC106962300	Four and a half LIM domains 1b. (294 aa)
	LOC106944871	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (817 aa)
	ENSPLAP00000028575	Spartin b. (271 aa)
	LOC106952074	SERTA domain containing 2b. (311 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (648 aa)
	SERTAD2	SERTA domain-containing protein 2-like. (311 aa)
	LOC106944807	Muscle segment homeobox 3. (212 aa)
	gdf9	Growth differentiation factor 9. (427 aa)
	nme6	Nucleoside diphosphate kinase. (182 aa)
	ENSPLAP00000029964	Sema domain-containing protein; Belongs to the semaphorin family. (595 aa)
	dip2a	Disco-interacting protein 2 homolog A. (1612 aa)
	msx1	Muscle segment homeobox 1a. (238 aa)
	LOC106938230	Sema domain-containing protein. (1052 aa)
	GREM1	Gremlin. (182 aa)
	LOC106953399	Sema domain-containing protein; Belongs to the semaphorin family. (771 aa)
	LOC106948096	Vestigial-like family member 4a. (248 aa)
	LOC106951425	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba; Belongs to the semaphorin family. (849 aa)
	LOC106951432	Semaphorin 4e; Belongs to the semaphorin family. (754 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	cgrrf1	Cell growth regulator with ring finger domain 1. (311 aa)
	LOC106954812	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1636 aa)
	LOC106949677	Si:ch211-129c21.1; Belongs to the semaphorin family. (806 aa)
	LOC106961712	Uncharacterized protein. (1003 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	LOC106954860	Disco-interacting protein 2 homolog Cb. (1615 aa)
	flcn	Folliculin. (554 aa)
	SEMA4F	Ssemaphorin 4F; Belongs to the semaphorin family. (841 aa)
	LOC106960985	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family. (1086 aa)
	st7l	Suppression of tumorigenicity 7 like. (553 aa)
	wnt3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
	LOC106959178	Uncharacterized protein. (1607 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	LOC106937635	Uncharacterized protein; Belongs to the semaphorin family. (714 aa)
	sema4d	Uncharacterized protein; Belongs to the semaphorin family. (853 aa)
	LOC106961822	WT1 transcription factor a. (445 aa)
	eaf2	ELL associated factor 2. (264 aa)
	LOC106962535	Disco-interacting protein 2 homolog Bb. (1507 aa)
	LOC106936529	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (702 aa)
	phb	Prohibitin. (271 aa)
	LOC106959606	Uncharacterized protein; Belongs to the semaphorin family. (889 aa)
	LOC106939239	Mothers against decapentaplegic homolog. (534 aa)
	SEMA6A	Semaphorin 6A. (609 aa)
	dcbld2	Discoidin, CUB and LCCL domain containing 2. (687 aa)
	SEMA3B	Semaphorin 3B; Belongs to the semaphorin family. (668 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (793 aa)
	sirt1	Sirtuin 1. (677 aa)
	ostn	Uncharacterized protein. (147 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (593 aa)
	slit1	Slit homolog 1a (Drosophila). (1496 aa)
	ENSPLAP00000004745	Spartin b. (271 aa)
	ndufs3	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (260 aa)
	cdkn2c	ANK_REP_REGION domain-containing protein. (161 aa)
	LOC106955125-2	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (151 aa)
	sema5a	Sema domain-containing protein. (1078 aa)
	vgll4	Vestigial-like family member 4b. (309 aa)
	dab2	DAB adaptor protein 2. (737 aa)
	LOC106950879	Disco-interacting protein 2 homolog Ba. (1342 aa)
	LOC106965029	Si:dkey-49n23.1; Belongs to the semaphorin family. (800 aa)
	LOC106934832	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (788 aa)
	LOC106938489	Uncharacterized protein; Belongs to the semaphorin family. (770 aa)
	ENSPLAP00000012053	Uncharacterized protein. (265 aa)
	sema6b	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family. (868 aa)
	ENSPLAP00000011711	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	crlf3	Cytokine receptor-like factor 3. (445 aa)
	LOC106944326	Mothers against decapentaplegic homolog. (503 aa)
	LOC106944344	Bone morphogenetic protein 10, like. (462 aa)
	ifrd1	Interferon-related developmental regulator 1. (428 aa)
	LOC106955203	Disco interacting protein 2 homolog C. (1610 aa)
	sema3e	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (766 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (761 aa)
	LOC106954575	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (135 aa)
	LOC106953690	Mitochondrial E3 ubiquitin protein ligase 1a. (357 aa)
	LOC106959995	Si:ch211-113g11.6; Belongs to the semaphorin family. (478 aa)
	wnt11	Wnt family member 11. (357 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	sema3g	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (755 aa)
	DCSTAMP	DC_STAMP domain-containing protein. (453 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000011711	LOC106939913	ENSPLAP00000011711	ENSPLAP00000028818	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	FZ domain-containing protein.	0.950
ENSPLAP00000011711	WNT11	ENSPLAP00000011711	ENSPLAP00000022826	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.616
ENSPLAP00000011711	epha4	ENSPLAP00000011711	ENSPLAP00000019283	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Eph receptor A4, like.	0.409
ENSPLAP00000011711	ryk	ENSPLAP00000011711	ENSPLAP00000017674	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Receptor like tyrosine kinase.	0.846
ENSPLAP00000011711	sfrp2	ENSPLAP00000011711	ENSPLAP00000031613	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2.	0.947
ENSPLAP00000011711	wnt11	ENSPLAP00000011711	ENSPLAP00000027361	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Wnt family member 11.	0.616
ENSPLAP00000021211	ENSPLAP00000029964	ENSPLAP00000021211	ENSPLAP00000029964	Sema domain-containing protein; Belongs to the semaphorin family.	Sema domain-containing protein; Belongs to the semaphorin family.	0.463
ENSPLAP00000021211	LOC106949677	ENSPLAP00000021211	ENSPLAP00000011085	Sema domain-containing protein; Belongs to the semaphorin family.	Si:ch211-129c21.1; Belongs to the semaphorin family.	0.463
ENSPLAP00000021211	LOC106951432	ENSPLAP00000021211	ENSPLAP00000015349	Sema domain-containing protein; Belongs to the semaphorin family.	Semaphorin 4e; Belongs to the semaphorin family.	0.463
ENSPLAP00000021211	cdk5	ENSPLAP00000021211	ENSPLAP00000027485	Sema domain-containing protein; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.528
ENSPLAP00000021211	sema4d	ENSPLAP00000021211	ENSPLAP00000008458	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein; Belongs to the semaphorin family.	0.463
ENSPLAP00000021539	LOC106938489	ENSPLAP00000021539	ENSPLAP00000012123	Uncharacterized protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.406
ENSPLAP00000021539	LOC106940045	ENSPLAP00000021539	ENSPLAP00000024175	Uncharacterized protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.701
ENSPLAP00000021539	cdk5	ENSPLAP00000021539	ENSPLAP00000027485	Uncharacterized protein.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.528
ENSPLAP00000029964	ENSPLAP00000021211	ENSPLAP00000029964	ENSPLAP00000021211	Sema domain-containing protein; Belongs to the semaphorin family.	Sema domain-containing protein; Belongs to the semaphorin family.	0.463
ENSPLAP00000029964	LOC106937635	ENSPLAP00000029964	ENSPLAP00000013854	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein; Belongs to the semaphorin family.	0.463
ENSPLAP00000029964	LOC106941245	ENSPLAP00000029964	ENSPLAP00000021813	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein; Belongs to the semaphorin family.	0.463
ENSPLAP00000029964	LOC106959606	ENSPLAP00000029964	ENSPLAP00000006870	Sema domain-containing protein; Belongs to the semaphorin family.	Uncharacterized protein; Belongs to the semaphorin family.	0.463
ENSPLAP00000029964	SEMA4F	ENSPLAP00000029964	ENSPLAP00000009836	Sema domain-containing protein; Belongs to the semaphorin family.	Ssemaphorin 4F; Belongs to the semaphorin family.	0.463
ENSPLAP00000031114	eaf2	ENSPLAP00000031114	ENSPLAP00000008121	FCP1 homology domain-containing protein.	ELL associated factor 2.	0.698