76 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBE2O	Ubiquitin conjugating enzyme E2 O. (1401 aa)
	rnf165	Ring finger protein 165a. (346 aa)
	LOC106944326	Mothers against decapentaplegic homolog. (503 aa)
	bmp2	Bone morphogenetic protein 2b. (409 aa)
	nog	Noggin; Belongs to the noggin family. (222 aa)
	ENSPLAP00000004745	Spartin b. (271 aa)
	htra3	HtrA serine peptidase 3a. (558 aa)
	smad7	Mothers against decapentaplegic homolog. (364 aa)
	LOC106956543	SMAD specific E3 ubiquitin protein ligase 1. (706 aa)
	ENSPLAP00000005767	SKI family transcriptional corepressor 1b. (691 aa)
	ENSPLAP00000005822	Metalloendopeptidase. (958 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (405 aa)
	LOC106953622	T-box transcription factor Ta. (421 aa)
	LOC106939239	Mothers against decapentaplegic homolog. (534 aa)
	LOC106949198	Uncharacterized protein. (275 aa)
	lemd3	LEM domain containing 3. (789 aa)
	grem2	Gremlin 2, DAN family BMP antagonist a. (192 aa)
	LOC106955590	Noggin; Belongs to the noggin family. (211 aa)
	fst	Follistatin a. (349 aa)
	dkk1	TNFR-Cys domain-containing protein. (251 aa)
	LOC106956402	RGM domain family, member D. (434 aa)
	ctdspl2	CTD small phosphatase like 2. (476 aa)
	sostdc1	Sclerostin domain containing 1a. (219 aa)
	ENSPLAP00000010696	Gremlin 1a, DAN family BMP antagonist. (159 aa)
	smad6	Mothers against decapentaplegic homolog. (490 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (645 aa)
	chrdl2	Chordin-like 2. (440 aa)
	b4galt5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5. (382 aa)
	ilk	Integrin linked kinase. (452 aa)
	LOC106944956	Ring finger protein 165b. (349 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (268 aa)
	fstl3	Follistatin-like 3 (secreted glycoprotein). (244 aa)
	LOC106958767	DAN domain family, member 5. (255 aa)
	foxh1	Forkhead box H1. (507 aa)
	GREM1	Gremlin. (182 aa)
	ENSPLAP00000017259	SKI family transcriptional corepressor 1. (720 aa)
	msx1	Muscle segment homeobox 1a. (238 aa)
	ENSPLAP00000017769	Integrin, alpha 3b; Belongs to the integrin alpha chain family. (846 aa)
	bmp1	Metalloendopeptidase. (970 aa)
	gdf5	Growth differentiation factor 5. (486 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	LOC106937460	Mothers against decapentaplegic homolog. (510 aa)
	LOC106951145	Uncharacterized protein; Belongs to the integrin alpha chain family. (915 aa)
	LOC106957970	Mothers against decapentaplegic homolog. (475 aa)
	LOC106945827	V-ski avian sarcoma viral oncogene homolog b. (672 aa)
	NOG	Noggin; Belongs to the noggin family. (212 aa)
	LOC106962619	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3. (403 aa)
	LOC106935788	FCP1 homology domain-containing protein. (473 aa)
	skil	SKI-like proto-oncogene a. (770 aa)
	fbxl15	F-box and leucine-rich repeat protein 15. (292 aa)
	ILK	Integrin linked kinase. (452 aa)
	LOC106959732	Mothers against decapentaplegic homolog. (332 aa)
	ENSPLAP00000025234	Uncharacterized protein. (152 aa)
	LOC106964417	Secreted frizzled-related protein 5. (318 aa)
	chrd	Chordin; Belongs to the chordin family. (933 aa)
	twsg1	Twisted gastrulation BMP signaling modulator 1. (222 aa)
	LOC106935579	Hemojuvelin BMP co-receptor. (419 aa)
	ccn1	Cellular communication network factor 1. (380 aa)
	ENSPLAP00000027090	C2 domain-containing protein. (54 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	numa1	Uncharacterized protein. (2535 aa)
	ENSPLAP00000028575	Spartin b. (271 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	ENSPLAP00000028836	V-ski avian sarcoma viral oncogene homolog a. (269 aa)
	vwc2l	Von Willebrand factor C domain containing 2 like. (225 aa)
	LOC106955430	Secreted frizzled-related protein 1a. (305 aa)
	LOC106944807	Muscle segment homeobox 3. (212 aa)
	ENSPLAP00000029815	SKI family transcriptional corepressor 2. (304 aa)
	LOC106960831	Sizzled. (304 aa)
	smurf2	HECT domain-containing protein. (417 aa)
	spart	Spartin a. (619 aa)
	gdf6	Growth differentiation factor 6a. (418 aa)
	bambi	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
	bmper	BMP binding endothelial regulator. (658 aa)
	fkbp8	Peptidylprolyl isomerase. (396 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000004745	spart	ENSPLAP00000004745	ENSPLAP00000030125	Spartin b.	Spartin a.	0.901
ENSPLAP00000005767	smad6	ENSPLAP00000005767	ENSPLAP00000011030	SKI family transcriptional corepressor 1b.	Mothers against decapentaplegic homolog.	0.634
ENSPLAP00000005822	LOC106960831	ENSPLAP00000005822	ENSPLAP00000029904	Metalloendopeptidase.	Sizzled.	0.585
ENSPLAP00000005822	bmp2	ENSPLAP00000005822	ENSPLAP00000003581	Metalloendopeptidase.	Bone morphogenetic protein 2b.	0.466
ENSPLAP00000005822	bmper	ENSPLAP00000005822	ENSPLAP00000030841	Metalloendopeptidase.	BMP binding endothelial regulator.	0.402
ENSPLAP00000005822	chrd	ENSPLAP00000005822	ENSPLAP00000025317	Metalloendopeptidase.	Chordin; Belongs to the chordin family.	0.903
ENSPLAP00000010696	GREM1	ENSPLAP00000010696	ENSPLAP00000016954	Gremlin 1a, DAN family BMP antagonist.	Gremlin.	0.898
ENSPLAP00000010696	bmp2	ENSPLAP00000010696	ENSPLAP00000003581	Gremlin 1a, DAN family BMP antagonist.	Bone morphogenetic protein 2b.	0.901
ENSPLAP00000010696	chrd	ENSPLAP00000010696	ENSPLAP00000025317	Gremlin 1a, DAN family BMP antagonist.	Chordin; Belongs to the chordin family.	0.422
ENSPLAP00000010696	gdf5	ENSPLAP00000010696	ENSPLAP00000018500	Gremlin 1a, DAN family BMP antagonist.	Growth differentiation factor 5.	0.756
ENSPLAP00000010696	gdf6	ENSPLAP00000010696	ENSPLAP00000030246	Gremlin 1a, DAN family BMP antagonist.	Growth differentiation factor 6a.	0.849
ENSPLAP00000010696	grem2	ENSPLAP00000010696	ENSPLAP00000007817	Gremlin 1a, DAN family BMP antagonist.	Gremlin 2, DAN family BMP antagonist a.	0.905
ENSPLAP00000017259	smad6	ENSPLAP00000017259	ENSPLAP00000011030	SKI family transcriptional corepressor 1.	Mothers against decapentaplegic homolog.	0.407
ENSPLAP00000017769	ILK	ENSPLAP00000017769	ENSPLAP00000024838	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Integrin linked kinase.	0.564
ENSPLAP00000017769	LOC106951145	ENSPLAP00000017769	ENSPLAP00000020351	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Uncharacterized protein; Belongs to the integrin alpha chain family.	0.936
ENSPLAP00000017769	ilk	ENSPLAP00000017769	ENSPLAP00000011483	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Integrin linked kinase.	0.564
ENSPLAP00000027090	ENSPLAP00000028836	ENSPLAP00000027090	ENSPLAP00000028836	C2 domain-containing protein.	V-ski avian sarcoma viral oncogene homolog a.	0.447
ENSPLAP00000027090	LOC106937460	ENSPLAP00000027090	ENSPLAP00000019866	C2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.769
ENSPLAP00000027090	LOC106939239	ENSPLAP00000027090	ENSPLAP00000006841	C2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.769
ENSPLAP00000027090	LOC106944326	ENSPLAP00000027090	ENSPLAP00000003577	C2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.769