30 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	htt	Huntingtin. (2588 aa)
	LOC106942609	CREB binding protein b. (2435 aa)
	LOC106941082	Huluwa. (217 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa)
	LOC106937213	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	LOC106935033	Nuclear receptor subfamily 1, group d, member 1. (565 aa)
	LOC106947649	Nuclear receptor subfamily 1, group D, member 4a. (580 aa)
	ENSPLAP00000009869	Uncharacterized protein. (143 aa)
	pex2	Peroxisomal biogenesis factor 2. (334 aa)
	ENSPLAP00000013662	E1A binding protein p300 b. (2525 aa)
	ENSPLAP00000014644	zf-RING_14 domain-containing protein. (96 aa)
	ENSPLAP00000014649	RBR-type E3 ubiquitin transferase. (166 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	ENSPLAP00000016728	Inhibitor_I29 domain-containing protein. (145 aa)
	rnf139	Ring finger protein 139. (701 aa)
	crebbp	CREB binding protein a. (2427 aa)
	xbp1	X-box binding protein 1. (384 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (255 aa)
	sirt6	Sirtuin 6. (351 aa)
	ENSPLAP00000028744	Ubiquitin-like domain-containing protein. (93 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (235 aa)
	gga3	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (742 aa)
	isoc2	Isochorismatase domain containing 2. (197 aa)
	fbxo4	F-box protein 4. (391 aa)
	fbxw11	F-box and WD repeat domain containing 11b. (527 aa)
	LOC106953779	Small EDRK-rich factor 2. (60 aa)
	utp25	UTP25 small subunit processor component. (747 aa)
	ENSPLAP00000004723	VHS domain-containing protein. (99 aa)
	sirt1	Sirtuin 1. (677 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	ENSPLAP00000009869	ENSPLAP00000015537	ENSPLAP00000009869	Cullin 3; Belongs to the cullin family.	Uncharacterized protein.	0.931
CUL3	LOC106937213	ENSPLAP00000015537	ENSPLAP00000007312	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.923
CUL3	fbxo4	ENSPLAP00000015537	ENSPLAP00000025801	Cullin 3; Belongs to the cullin family.	F-box protein 4.	0.794
CUL3	fbxw11	ENSPLAP00000015537	ENSPLAP00000025587	Cullin 3; Belongs to the cullin family.	F-box and WD repeat domain containing 11b.	0.931
ENSPLAP00000009869	CUL3	ENSPLAP00000009869	ENSPLAP00000015537	Uncharacterized protein.	Cullin 3; Belongs to the cullin family.	0.931
ENSPLAP00000009869	LOC106937213	ENSPLAP00000009869	ENSPLAP00000007312	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.931
ENSPLAP00000009869	fbxo4	ENSPLAP00000009869	ENSPLAP00000025801	Uncharacterized protein.	F-box protein 4.	0.903
ENSPLAP00000013662	LOC106935033	ENSPLAP00000013662	ENSPLAP00000008701	E1A binding protein p300 b.	Nuclear receptor subfamily 1, group d, member 1.	0.408
ENSPLAP00000013662	LOC106942609	ENSPLAP00000013662	ENSPLAP00000005927	E1A binding protein p300 b.	CREB binding protein b.	0.995
ENSPLAP00000013662	LOC106947649	ENSPLAP00000013662	ENSPLAP00000009838	E1A binding protein p300 b.	Nuclear receptor subfamily 1, group D, member 4a.	0.408
ENSPLAP00000013662	crebbp	ENSPLAP00000013662	ENSPLAP00000001834	E1A binding protein p300 b.	CREB binding protein a.	0.995
ENSPLAP00000013662	htt	ENSPLAP00000013662	ENSPLAP00000005791	E1A binding protein p300 b.	Huntingtin.	0.743
ENSPLAP00000013662	sirt1	ENSPLAP00000013662	ENSPLAP00000005614	E1A binding protein p300 b.	Sirtuin 1.	0.798
ENSPLAP00000013662	sirt6	ENSPLAP00000013662	ENSPLAP00000029180	E1A binding protein p300 b.	Sirtuin 6.	0.430
ENSPLAP00000014644	htt	ENSPLAP00000014644	ENSPLAP00000005791	zf-RING_14 domain-containing protein.	Huntingtin.	0.575
ENSPLAP00000014644	mul1	ENSPLAP00000014644	ENSPLAP00000015130	zf-RING_14 domain-containing protein.	Mitochondrial E3 ubiquitin protein ligase 1b.	0.628
ENSPLAP00000014649	htt	ENSPLAP00000014649	ENSPLAP00000005791	RBR-type E3 ubiquitin transferase.	Huntingtin.	0.575
ENSPLAP00000014649	mul1	ENSPLAP00000014649	ENSPLAP00000015130	RBR-type E3 ubiquitin transferase.	Mitochondrial E3 ubiquitin protein ligase 1b.	0.628
ENSPLAP00000016728	ctsh	ENSPLAP00000016728	ENSPLAP00000027840	Inhibitor_I29 domain-containing protein.	Cathepsin H; Belongs to the peptidase C1 family.	0.443
ENSPLAP00000028744	htt	ENSPLAP00000028744	ENSPLAP00000005791	Ubiquitin-like domain-containing protein.	Huntingtin.	0.575