(44 nodes) Cellular response to glucose starvation network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	zc3h12a	Zinc finger CCCH-type containing 12A. (627 aa)
	tbl2	Transducin (beta)-like 2. (441 aa)
	ENSPLAP00000002770	Basic helix-loop-helix family, member a15. (192 aa)
	xbp1	X-box binding protein 1. (384 aa)
	LOC106963230	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (319 aa)
	ENSPLAP00000003531	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
	sirt1	Sirtuin 1. (677 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	LOC106949189	Si:ch211-117c9.1. (696 aa)
	brsk1	Protein kinase domain-containing protein. (848 aa)
	sik2	Salt-inducible kinase 2b. (933 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	nuak2	NUAK family, SNF1-like kinase, 2. (606 aa)
	prkag3	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (340 aa)
	itfg2	Integrin alpha FG-GAP repeat containing 2. (433 aa)
	kptn	Kaptin (actin binding protein). (440 aa)
	pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1325 aa)
	prkag1	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (329 aa)
	LOC106951552	Si:dkey-206d17.12. (404 aa)
	LOC106959558	Protein kinase domain-containing protein. (760 aa)
	LOC106936283	Si:dkey-16p21.7. (727 aa)
	ENSPLAP00000013433	UBA domain-containing protein. (448 aa)
	LOC106953474	Cytoplasmic polyadenylation element binding protein 4a. (763 aa)
	pick1	Protein interacting with prkca 1. (409 aa)
	impact	Impact RWD domain protein. (323 aa)
	LOC106939808	Si:ch211-22d5.2; Belongs to the protein kinase superfamily. (435 aa)
	LOC106940692	Uncharacterized protein. (654 aa)
	LOC106940689	Salt-inducible kinase 1. (806 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1104 aa)
	LOC106960832	NUAK family, SNF1-like kinase, 1b. (661 aa)
	sesn1	Sestrin 1. (545 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
	LOC106952592	Non-specific serine/threonine protein kinase. (557 aa)
	LOC106953096	Si:ch211-125a15.1. (452 aa)
	LOC106937241	Uncharacterized protein. (184 aa)
	LOC106949811	Si:zfos-80g12.1. (444 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (564 aa)
	rrp8	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (548 aa)
	LOC106949141	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (544 aa)
	ENSPLAP00000027489	Protein kinase domain-containing protein. (92 aa)
	LOC106934749	Protein kinase domain-containing protein. (92 aa)
	LOC106960824	Sestrin 2. (558 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (876 aa)
	ENSPLAP00000031447	Protein kinase domain-containing protein. (364 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000003531	LOC106940692	ENSPLAP00000003531	ENSPLAP00000015522	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.708
ENSPLAP00000003531	LOC106949141	ENSPLAP00000003531	ENSPLAP00000025795	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b.	0.708
ENSPLAP00000003531	LOC106949189	ENSPLAP00000003531	ENSPLAP00000007811	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Si:ch211-117c9.1.	0.443
ENSPLAP00000003531	LOC106960832	ENSPLAP00000003531	ENSPLAP00000016349	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	NUAK family, SNF1-like kinase, 1b.	0.433
ENSPLAP00000003531	LOC106963230	ENSPLAP00000003531	ENSPLAP00000003372	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit.	0.708
ENSPLAP00000003531	nuak2	ENSPLAP00000003531	ENSPLAP00000010604	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	NUAK family, SNF1-like kinase, 2.	0.448
ENSPLAP00000003531	pik3c3	ENSPLAP00000003531	ENSPLAP00000030684	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.582
ENSPLAP00000003531	pik3r4	ENSPLAP00000003531	ENSPLAP00000012301	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.587
ENSPLAP00000003531	prkag1	ENSPLAP00000003531	ENSPLAP00000012384	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit.	0.708
ENSPLAP00000003531	prkag3	ENSPLAP00000003531	ENSPLAP00000011296	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit.	0.708
ENSPLAP00000013433	LOC106934749	ENSPLAP00000013433	ENSPLAP00000028883	UBA domain-containing protein.	Protein kinase domain-containing protein.	0.694
ENSPLAP00000013433	LOC106952592	ENSPLAP00000013433	ENSPLAP00000020459	UBA domain-containing protein.	Non-specific serine/threonine protein kinase.	0.449
ENSPLAP00000027489	LOC106940692	ENSPLAP00000027489	ENSPLAP00000015522	Protein kinase domain-containing protein.	Uncharacterized protein.	0.708
ENSPLAP00000027489	LOC106949141	ENSPLAP00000027489	ENSPLAP00000025795	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b.	0.708
ENSPLAP00000027489	LOC106963230	ENSPLAP00000027489	ENSPLAP00000003372	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit.	0.708
ENSPLAP00000027489	pik3c3	ENSPLAP00000027489	ENSPLAP00000030684	Protein kinase domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.582
ENSPLAP00000027489	pik3r4	ENSPLAP00000027489	ENSPLAP00000012301	Protein kinase domain-containing protein.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.587
ENSPLAP00000027489	prkag1	ENSPLAP00000027489	ENSPLAP00000012384	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit.	0.708
ENSPLAP00000027489	prkag3	ENSPLAP00000027489	ENSPLAP00000011296	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit.	0.708
ENSPLAP00000031447	LOC106940692	ENSPLAP00000031447	ENSPLAP00000015522	Protein kinase domain-containing protein.	Uncharacterized protein.	0.708