30 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	agt	Angiotensinogen; Belongs to the serpin family. (462 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	LOC106936075	Uncharacterized protein. (222 aa)
	aida	Axin interactor, dorsalization associated. (305 aa)
	SPRY3	Sprouty RTK signaling antagonist 3. (294 aa)
	LOC106954089	Dual specificity phosphatase 19a. (198 aa)
	sh2b3	SH2B adaptor protein 3. (710 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (358 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
	LOC106950393	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (204 aa)
	LOC106962464	Progestin and adipoQ receptor family member IIIa. (375 aa)
	LOC106935197	SSD domain-containing protein. (776 aa)
	LOC106946506	Sprouty RTK signaling antagonist 2. (314 aa)
	nf1	Neurofibromin 1b. (2795 aa)
	LOC106957905	Progestin and adipoQ receptor family member IIIb. (311 aa)
	spry4	Sprouty homolog 4 (Drosophila). (381 aa)
	LOC106947136	Si:dkey-175m17.7. (893 aa)
	tmem130	PKD domain-containing protein. (308 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC106943151	3-hydroxy-3-methylglutaryl coenzyme A reductase. (867 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (506 aa)
	LOC106939157	Bone morphogenetic protein 16. (477 aa)
	dusp10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	gba	Glucosylceramidase. (522 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	LOC106946887	Apolipoprotein Ea. (251 aa)
	LOC106938463	Apolipoprotein Eb. (265 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (601 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC106942092	3-hydroxy-3-methylglutaryl coenzyme A reductase. (849 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106935197	LOC106938463	ENSPLAP00000000481	ENSPLAP00000027342	SSD domain-containing protein.	Apolipoprotein Eb.	0.487
LOC106935197	LOC106942092	ENSPLAP00000000481	ENSPLAP00000019738	SSD domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.898
LOC106935197	LOC106943151	ENSPLAP00000000481	ENSPLAP00000031295	SSD domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.898
LOC106936075	LOC106957905	ENSPLAP00000017930	ENSPLAP00000005128	Uncharacterized protein.	Progestin and adipoQ receptor family member IIIb.	0.405
LOC106936075	LOC106962464	ENSPLAP00000017930	ENSPLAP00000010450	Uncharacterized protein.	Progestin and adipoQ receptor family member IIIa.	0.405
LOC106938463	LOC106935197	ENSPLAP00000027342	ENSPLAP00000000481	Apolipoprotein Eb.	SSD domain-containing protein.	0.487
LOC106938463	agt	ENSPLAP00000027342	ENSPLAP00000022751	Apolipoprotein Eb.	Angiotensinogen; Belongs to the serpin family.	0.510
LOC106938463	cav1	ENSPLAP00000027342	ENSPLAP00000026042	Apolipoprotein Eb.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.422
LOC106938463	cav3	ENSPLAP00000027342	ENSPLAP00000011450	Apolipoprotein Eb.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.452
LOC106939157	bmp4	ENSPLAP00000029728	ENSPLAP00000019124	Bone morphogenetic protein 16.	Bone morphogenetic protein 4.	0.888
LOC106942092	LOC106935197	ENSPLAP00000019738	ENSPLAP00000000481	3-hydroxy-3-methylglutaryl coenzyme A reductase.	SSD domain-containing protein.	0.898
LOC106943151	LOC106935197	ENSPLAP00000031295	ENSPLAP00000000481	3-hydroxy-3-methylglutaryl coenzyme A reductase.	SSD domain-containing protein.	0.898
LOC106946506	spry1	ENSPLAP00000002737	ENSPLAP00000011825	Sprouty RTK signaling antagonist 2.	Sprouty homolog 1, antagonist of FGF signaling (Drosophila).	0.762
LOC106946887	agt	ENSPLAP00000028349	ENSPLAP00000022751	Apolipoprotein Ea.	Angiotensinogen; Belongs to the serpin family.	0.401
LOC106950393	cav3	ENSPLAP00000011427	ENSPLAP00000011450	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.959
LOC106950393	sfrp2	ENSPLAP00000011427	ENSPLAP00000031613	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Secreted frizzled-related protein 2.	0.447
LOC106954089	LOC106957905	ENSPLAP00000014221	ENSPLAP00000005128	Dual specificity phosphatase 19a.	Progestin and adipoQ receptor family member IIIb.	0.407
LOC106954089	LOC106962464	ENSPLAP00000014221	ENSPLAP00000010450	Dual specificity phosphatase 19a.	Progestin and adipoQ receptor family member IIIa.	0.407
LOC106957905	LOC106936075	ENSPLAP00000005128	ENSPLAP00000017930	Progestin and adipoQ receptor family member IIIb.	Uncharacterized protein.	0.405
LOC106957905	LOC106954089	ENSPLAP00000005128	ENSPLAP00000014221	Progestin and adipoQ receptor family member IIIb.	Dual specificity phosphatase 19a.	0.407