(34 nodes) Defense response to Gram-positive bacterium network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106949328	Uncharacterized protein. (131 aa)
	adam17	ADAM metallopeptidase domain 17b. (841 aa)
	ENSPLAP00000000157	RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (128 aa)
	ENSPLAP00000001245	Jacalin-type lectin domain-containing protein. (162 aa)
	MPEG1	Macrophage expressed 1. (714 aa)
	LOC106939433	MACPF domain-containing protein. (706 aa)
	ENSPLAP00000004911	RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (184 aa)
	ENSPLAP00000005421	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (176 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (581 aa)
	LOC106957837	Uncharacterized protein. (489 aa)
	LOC106945134	Peptidoglycan recognition protein 5. (177 aa)
	ENSPLAP00000008499	Uncharacterized protein. (222 aa)
	IL18	Uncharacterized protein. (218 aa)
	ENSPLAP00000011139	Uncharacterized protein. (163 aa)
	LOC106954181	ADAM metallopeptidase domain 17a. (859 aa)
	ENSPLAP00000013918	TNFR-Cys domain-containing protein. (240 aa)
	LOC106949541	Peptidoglycan recognition protein 6. (471 aa)
	ENSPLAP00000015843	Uncharacterized protein. (178 aa)
	nod2	Nucleotide-binding oligomerization domain containing 2. (963 aa)
	ENSPLAP00000018100	CARD domain-containing protein. (151 aa)
	LOC106938220	Uncharacterized protein. (345 aa)
	LOC106940496	Interleukin-1. (247 aa)
	LOC106949327	Interleukin 17a/f1. (155 aa)
	ENSPLAP00000020693	RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (132 aa)
	ENSPLAP00000020699	RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (147 aa)
	LOC106935001	Tumor necrosis factor a (TNF superfamily, member 2); Belongs to the tumor necrosis factor family. (247 aa)
	PLA2G1B	Phospholipase A(2). (147 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (577 aa)
	LOC106949028	Phospholipase A(2). (149 aa)
	ENSPLAP00000028279	TNFR-Cys domain-containing protein. (257 aa)
	ppp1r11	Protein phosphatase 1, regulatory (inhibitor) subunit 11. (123 aa)
	nod1	Nucleotide-binding oligomerization domain containing 1. (941 aa)
	ENSPLAP00000029430	Si:ch211-108d22.2. (1498 aa)
	drosha	Uncharacterized protein. (1313 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000005421	LOC106940496	ENSPLAP00000005421	ENSPLAP00000018515	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	Interleukin-1.	0.416
ENSPLAP00000005421	ripk2	ENSPLAP00000005421	ENSPLAP00000005915	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	Receptor-interacting serine-threonine kinase 2.	0.603
ENSPLAP00000008499	ENSPLAP00000029430	ENSPLAP00000008499	ENSPLAP00000029430	Uncharacterized protein.	Si:ch211-108d22.2.	0.540
ENSPLAP00000008499	IL18	ENSPLAP00000008499	ENSPLAP00000009040	Uncharacterized protein.	Uncharacterized protein.	0.773
ENSPLAP00000008499	LOC106940496	ENSPLAP00000008499	ENSPLAP00000018515	Uncharacterized protein.	Interleukin-1.	0.783
ENSPLAP00000008499	nod1	ENSPLAP00000008499	ENSPLAP00000029365	Uncharacterized protein.	Nucleotide-binding oligomerization domain containing 1.	0.540
ENSPLAP00000008499	nod2	ENSPLAP00000008499	ENSPLAP00000018069	Uncharacterized protein.	Nucleotide-binding oligomerization domain containing 2.	0.540
ENSPLAP00000011139	ENSPLAP00000015843	ENSPLAP00000011139	ENSPLAP00000015843	Uncharacterized protein.	Uncharacterized protein.	0.567
ENSPLAP00000011139	LOC106940496	ENSPLAP00000011139	ENSPLAP00000018515	Uncharacterized protein.	Interleukin-1.	0.439
ENSPLAP00000011139	LOC106949327	ENSPLAP00000011139	ENSPLAP00000018926	Uncharacterized protein.	Interleukin 17a/f1.	0.957
ENSPLAP00000011139	LOC106949328	ENSPLAP00000011139	ENSPLAP00000031591	Uncharacterized protein.	Uncharacterized protein.	0.909
ENSPLAP00000013918	LOC106935001	ENSPLAP00000013918	ENSPLAP00000025103	TNFR-Cys domain-containing protein.	Tumor necrosis factor a (TNF superfamily, member 2); Belongs to the tumor necrosis factor family.	0.795
ENSPLAP00000015843	ENSPLAP00000011139	ENSPLAP00000015843	ENSPLAP00000011139	Uncharacterized protein.	Uncharacterized protein.	0.567
ENSPLAP00000015843	LOC106940496	ENSPLAP00000015843	ENSPLAP00000018515	Uncharacterized protein.	Interleukin-1.	0.413
ENSPLAP00000015843	LOC106949327	ENSPLAP00000015843	ENSPLAP00000018926	Uncharacterized protein.	Interleukin 17a/f1.	0.567
ENSPLAP00000015843	LOC106949328	ENSPLAP00000015843	ENSPLAP00000031591	Uncharacterized protein.	Uncharacterized protein.	0.567
ENSPLAP00000018100	ENSPLAP00000029430	ENSPLAP00000018100	ENSPLAP00000029430	CARD domain-containing protein.	Si:ch211-108d22.2.	0.433
ENSPLAP00000018100	LOC106938220	ENSPLAP00000018100	ENSPLAP00000018117	CARD domain-containing protein.	Uncharacterized protein.	0.716
ENSPLAP00000018100	nod1	ENSPLAP00000018100	ENSPLAP00000029365	CARD domain-containing protein.	Nucleotide-binding oligomerization domain containing 1.	0.433
ENSPLAP00000018100	nod2	ENSPLAP00000018100	ENSPLAP00000018069	CARD domain-containing protein.	Nucleotide-binding oligomerization domain containing 2.	0.433