50 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wfs1	Wolfram syndrome 1b (wolframin). (971 aa)
	LOC106963867	Uncharacterized protein. (597 aa)
	LOC106963657	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa)
	LOC106954737	Zgc:123321. (235 aa)
	tmem106b	Transmembrane protein 106Ba. (262 aa)
	znhit6	Zinc finger HIT-type containing 6. (424 aa)
	LOC106942681	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (235 aa)
	LOC106950393	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (204 aa)
	LOC106959088	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
	LOC106950370	Uncharacterized protein. (200 aa)
	LOC106941066	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	tmtc4	Transmembrane O-mannosyltransferase targeting cadherins 4. (741 aa)
	ENSPLAP00000005282	Sodium/potassium transporting ATPase interacting 1. (196 aa)
	nkain2	Sodium/potassium transporting ATPase interacting 2. (208 aa)
	LOC106939331	Uncharacterized protein. (681 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (255 aa)
	vcpkmt	Valosin containing protein lysine (K) methyltransferase. (223 aa)
	nop58	NOP58 ribonucleoprotein homolog (yeast). (534 aa)
	LOC106941936	Uncharacterized protein. (94 aa)
	atp1b3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa)
	LOC106959891	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (346 aa)
	atp6v0a2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (850 aa)
	ENSPLAP00000014227	Uncharacterized protein. (67 aa)
	tmem106a	Transmembrane protein 106A. (244 aa)
	RALB	RAS like proto-oncogene B. (207 aa)
	clpp	ATP-dependent Clp protease proteolytic subunit. (269 aa)
	selenos	Selenoprotein S. (190 aa)
	LOC106936733	Peroxisomal biogenesis factor 19. (256 aa)
	LOC106936741	Uncharacterized protein. (292 aa)
	LOC106959994	Protein S100; Belongs to the S-100 family. (101 aa)
	yipf5	Protein YIPF. (257 aa)
	nufip1	C2H2-type domain-containing protein. (536 aa)
	trpc1	Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
	pih1d1	PIH1 domain containing 1. (285 aa)
	atp5if1	Uncharacterized protein. (108 aa)
	LOC106936522	V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
	ncstn	Ncstrn_small domain-containing protein. (604 aa)
	AR	Androgen receptor. (757 aa)
	ATP6V0A1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	pex26	Uncharacterized protein. (297 aa)
	LOC106945617	ATP synthase inhibitory factor subunit 1b. (107 aa)
	LOC106963895	Uncharacterized protein. (524 aa)
	tcirg1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (826 aa)
	pelp1	Proline, glutamate and leucine rich protein 1. (1266 aa)
	ENSPLAP00000029398	Wolfram syndrome 1a (wolframin). (775 aa)
	LOC106936849	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (93 aa)
	TMEM106B	Transmembrane protein 106B. (269 aa)
	atp1b2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (285 aa)
	snu13	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	LOC106939331	ENSPLAP00000025137	ENSPLAP00000005224	Androgen receptor.	Uncharacterized protein.	0.924
ATP6V0A1	LOC106941066	ENSPLAP00000025748	ENSPLAP00000006754	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.988
ATP6V0A1	LOC106959088	ENSPLAP00000025748	ENSPLAP00000008251	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.857
ATP6V0A1	LOC106963657	ENSPLAP00000025748	ENSPLAP00000013083	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.799
ATP6V0A1	atp6v0a2	ENSPLAP00000025748	ENSPLAP00000001827	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.831
ATP6V0A1	tcirg1	ENSPLAP00000025748	ENSPLAP00000028515	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.832
ENSPLAP00000014227	cav1	ENSPLAP00000014227	ENSPLAP00000026042	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.435
ENSPLAP00000029398	wfs1	ENSPLAP00000029398	ENSPLAP00000023999	Wolfram syndrome 1a (wolframin).	Wolfram syndrome 1b (wolframin).	0.905
LOC106936522	LOC106941066	ENSPLAP00000024311	ENSPLAP00000006754	V-ral simian leukemia viral oncogene homolog Aa (ras related).	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.403
LOC106936522	cav1	ENSPLAP00000024311	ENSPLAP00000026042	V-ral simian leukemia viral oncogene homolog Aa (ras related).	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.430
LOC106936733	pex26	ENSPLAP00000017673	ENSPLAP00000027247	Peroxisomal biogenesis factor 19.	Uncharacterized protein.	0.461
LOC106936741	pex26	ENSPLAP00000017763	ENSPLAP00000027247	Uncharacterized protein.	Uncharacterized protein.	0.461
LOC106936849	LOC106941936	ENSPLAP00000029474	ENSPLAP00000002622	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Uncharacterized protein.	0.578
LOC106936849	LOC106942681	ENSPLAP00000029474	ENSPLAP00000011565	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.578
LOC106936849	LOC106959891	ENSPLAP00000029474	ENSPLAP00000002209	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.578
LOC106936849	atp1b2	ENSPLAP00000029474	ENSPLAP00000030525	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.578
LOC106936849	atp1b3	ENSPLAP00000029474	ENSPLAP00000002413	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.578
LOC106939331	AR	ENSPLAP00000005224	ENSPLAP00000025137	Uncharacterized protein.	Androgen receptor.	0.924
LOC106941066	ATP6V0A1	ENSPLAP00000006754	ENSPLAP00000025748	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.988
LOC106941066	LOC106936522	ENSPLAP00000006754	ENSPLAP00000024311	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-ral simian leukemia viral oncogene homolog Aa (ras related).	0.403