STRINGSTRING
dna2 dna2 mocs1 mocs1 dpyd dpyd ENSPLAP00000030472 ENSPLAP00000030472 ino80d ino80d ppat ppat serp1 serp1 MUTYH MUTYH brip1 brip1 ndufs7 ndufs7 cdk5rap1 cdk5rap1 NDUFS1-2 NDUFS1-2 NDUFS8 NDUFS8 LOC106947655 LOC106947655 ercc2 ercc2 rsad1 rsad1 ireb2 ireb2 LOC106938145 LOC106938145 cdkal1 cdkal1 nubpl nubpl lias lias aco1 aco1 LOC106938168 LOC106938168 NDUFS1 NDUFS1 ciapin1 ciapin1 rtel1 rtel1 nubp2 nubp2 ACO2 ACO2 LOC106940666 LOC106940666 SDHB SDHB ciao3 ciao3 elp3 elp3 pold1 pold1 etfdh etfdh LOC106950295 LOC106950295 prim2 prim2 rsad2 rsad2 LOC106960537 LOC106960537 ddx11 ddx11 NDUFV1 NDUFV1 isca2 isca2 dph2 dph2 dph1 dph1 ENSPLAP00000005060 ENSPLAP00000005060 LOC106938805 LOC106938805 nthl1 nthl1 LOC106958340 LOC106958340 pole pole LOC106935930 LOC106935930
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dna2Uncharacterized protein. (1190 aa)
mocs1Molybdenum cofactor synthesis 1. (397 aa)
dpydDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1026 aa)
ENSPLAP00000030472Uncharacterized protein. (97 aa)
ino80dINO80 complex subunit Da. (1006 aa)
ppatAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
serp1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (523 aa)
brip1BRCA1 interacting protein C-terminal helicase 1. (1163 aa)
ndufs7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (220 aa)
cdk5rap1CDK5 regulatory subunit associated protein 1. (580 aa)
NDUFS1-2NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (731 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (208 aa)
LOC106947655tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). (749 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
rsad1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (428 aa)
ireb2Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (990 aa)
LOC106938145Uncharacterized protein. (191 aa)
cdkal1CDK5 regulatory subunit associated protein 1-like 1. (535 aa)
nubplNucleotide binding protein-like. (330 aa)
liasLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (474 aa)
aco1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (870 aa)
LOC106938168NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae). (250 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1. (611 aa)
ciapin1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (313 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1177 aa)
nubp2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (268 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
LOC106940666NCK associated protein 5. (1862 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
ciao3Nuclear prelamin A recognition factor-like; Belongs to the NARF family. (476 aa)
elp3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (538 aa)
pold1DNA polymerase. (1105 aa)
etfdhElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (622 aa)
LOC106950295Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (504 aa)
rsad2Radical S-adenosyl methionine domain containing 2. (350 aa)
LOC106960537NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (472 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (897 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (436 aa)
isca2Iron-sulfur cluster assembly 2. (176 aa)
dph22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (467 aa)
dph12-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (383 aa)
ENSPLAP000000050602Fe-2S ferredoxin-type domain-containing protein. (260 aa)
LOC106938805Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (322 aa)
nthl1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (300 aa)
LOC106958340Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
LOC106935930Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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