107 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106951603	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (410 aa)
	sulf1	Sulfatase 1. (1143 aa)
	ebp	EBP cholestenol delta-isomerase. (229 aa)
	edar	Ectodysplasin A receptor. (536 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	LOC106961202	MADS-box domain-containing protein. (471 aa)
	LOC106941263	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	ENSPLAP00000004009	Nuclear receptor binding SET domain protein 2. (487 aa)
	ENSPLAP00000004039	PWWP domain-containing protein. (171 aa)
	ptprc	Uncharacterized protein. (884 aa)
	ENSPLAP00000004359	NGFI-A binding protein 2 (EGR1 binding protein 2). (460 aa)
	LOC106952760	RAP1A, member of RAS oncogene family a. (185 aa)
	LOC106941801	Uncharacterized protein. (184 aa)
	ostn	Uncharacterized protein. (147 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (778 aa)
	LOC106940094	Fibronectin type-III domain-containing protein. (932 aa)
	ENSPLAP00000006015	TPR_REGION domain-containing protein. (211 aa)
	ttc9	Tetratricopeptide repeat domain 9. (203 aa)
	LOC106961870	Abl-interactor 1b. (496 aa)
	LOC106937739	Myocyte enhancer factor 2d. (499 aa)
	ENSPLAP00000006928	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (65 aa)
	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2). (499 aa)
	EPYC	Epiphycan. (282 aa)
	ABI1	Abl-interactor 1a. (550 aa)
	pdgfc	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (361 aa)
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	sema4d	Uncharacterized protein; Belongs to the semaphorin family. (853 aa)
	ENSPLAP00000008584	Uncharacterized protein. (274 aa)
	MEF2D	MADS-box domain-containing protein. (496 aa)
	rab23	RAB23, member RAS oncogene family. (235 aa)
	anxa6	Annexin. (642 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	rap1a	RAP1A, member of RAS oncogene family b. (185 aa)
	mcph1	Microcephalin 1. (808 aa)
	LOC106939030	Vitamin K epoxide reductase complex, subunit 1. (167 aa)
	foxn3	Checkpoint suppressor 1. (485 aa)
	LOC106937107	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC106957674	Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (780 aa)
	LOC106949677	Si:ch211-129c21.1; Belongs to the semaphorin family. (806 aa)
	LOC106954227	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	LOC106935574	Phosphatase, orphan 2. (244 aa)
	frem1	Fras1 related extracellular matrix 1a. (961 aa)
	LOC106938496	Uncharacterized protein. (458 aa)
	sh2b3	SH2B adaptor protein 3. (710 aa)
	LOC106957509	Fras1 related extracellular matrix 1b. (1507 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	ENSPLAP00000013169	Uncharacterized protein. (99 aa)
	atg9a	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (874 aa)
	ENSPLAP00000013662	E1A binding protein p300 b. (2525 aa)
	ENSPLAP00000013773	Gla domain-containing protein. (172 aa)
	SPNS2	Sphingolipid transporter 2. (490 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	ankrd11	Ankyrin repeat domain 11. (2824 aa)
	ENSPLAP00000014986	Uncharacterized protein. (177 aa)
	ENSPLAP00000015049	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (272 aa)
	LOC106951432	Semaphorin 4e; Belongs to the semaphorin family. (754 aa)
	LOC106948090	Glycoprotein IX (platelet). (260 aa)
	sp5	Sp5 transcription factor a. (375 aa)
	dhrs3	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	LOC106939787	Uncharacterized protein. (1147 aa)
	srf	Serum response factor b. (601 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
	msx1	Muscle segment homeobox 1a. (238 aa)
	LOC106964852	Extracellular sulfatase. (885 aa)
	slc38a10	Solute carrier family 38 member 10. (1075 aa)
	trip11	Thyroid hormone receptor interactor 11. (1953 aa)
	LOC106940501	Leucine rich repeat containing 17. (263 aa)
	LOC106957301	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (261 aa)
	mbtps2	Membrane-bound transcription factor peptidase, site 2. (497 aa)
	LOC106954618	Tyrosine-protein kinase. (527 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	tsku	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (348 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	LOC106953209	Golgi glycoprotein 1b. (1146 aa)
	ENSPLAP00000020652	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (731 aa)
	ENSPLAP00000020663	Stealth_CR4 domain-containing protein. (139 aa)
	ENSPLAP00000020756	Uncharacterized protein. (289 aa)
	LOC106938905	Protein tyrosine phosphatase non-receptor type 11b. (581 aa)
	ecm1	Uncharacterized protein. (483 aa)
	LOC106939464	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (797 aa)
	lepr	Uncharacterized protein. (645 aa)
	LOC106940239	Ras-related protein Rap-1b. (184 aa)
	LOC106949284	Sphingomyelin phosphodiesterase 3, neutral. (549 aa)
	LOC106941016	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (426 aa)
	gnptab	Uncharacterized protein. (333 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	LOC106955505	Uncharacterized protein. (849 aa)
	trim45	Tripartite motif containing 45. (589 aa)
	atp6ap1	ATPase H+ transporting accessory protein 1a. (489 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	fam20c	FAM20C golgi associated secretory pathway kinase a. (569 aa)
	LOC106962322	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	LOC106964297	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (727 aa)
	ENSPLAP00000028265	LRRNT domain-containing protein. (100 aa)
	LOC106961570	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (792 aa)
	LOC106939157	Bone morphogenetic protein 16. (477 aa)
	ENSPLAP00000029964	Sema domain-containing protein; Belongs to the semaphorin family. (595 aa)
	ENSPLAP00000030099	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
	LOC106950777	Histone acetyltransferase KAT2A-like. (797 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	LOC106942256	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
	lrrk1	Leucine-rich repeat kinase 1. (2013 aa)
	EVC	EvC ciliary complex subunit 1. (967 aa)
	mef2d	MADS-box domain-containing protein. (173 aa)
	phex	Phosphate regulating endopeptidase homolog, X-linked. (710 aa)
	LOC106954613	ATPase H+ transporting accessory protein 1b. (449 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	LOC106954618	ENSPLAP00000008043	ENSPLAP00000018623	Abl-interactor 1a.	Tyrosine-protein kinase.	0.507
ABI1	LOC106961870	ENSPLAP00000008043	ENSPLAP00000006599	Abl-interactor 1a.	Abl-interactor 1b.	0.903
ABI1	SRC	ENSPLAP00000008043	ENSPLAP00000014667	Abl-interactor 1a.	Tyrosine-protein kinase.	0.507
ENSPLAP00000004009	ENSPLAP00000013662	ENSPLAP00000004009	ENSPLAP00000013662	Nuclear receptor binding SET domain protein 2.	E1A binding protein p300 b.	0.564
ENSPLAP00000004009	LOC106939464	ENSPLAP00000004009	ENSPLAP00000021234	Nuclear receptor binding SET domain protein 2.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.442
ENSPLAP00000004009	LOC106950777	ENSPLAP00000004009	ENSPLAP00000030148	Nuclear receptor binding SET domain protein 2.	Histone acetyltransferase KAT2A-like.	0.442
ENSPLAP00000004009	LOC106961570	ENSPLAP00000004009	ENSPLAP00000028466	Nuclear receptor binding SET domain protein 2.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.442
ENSPLAP00000004009	ankrd11	ENSPLAP00000004009	ENSPLAP00000014814	Nuclear receptor binding SET domain protein 2.	Ankyrin repeat domain 11.	0.488
ENSPLAP00000004039	ENSPLAP00000013662	ENSPLAP00000004039	ENSPLAP00000013662	PWWP domain-containing protein.	E1A binding protein p300 b.	0.564
ENSPLAP00000004039	LOC106939464	ENSPLAP00000004039	ENSPLAP00000021234	PWWP domain-containing protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.442
ENSPLAP00000004039	LOC106950777	ENSPLAP00000004039	ENSPLAP00000030148	PWWP domain-containing protein.	Histone acetyltransferase KAT2A-like.	0.442
ENSPLAP00000004039	LOC106961570	ENSPLAP00000004039	ENSPLAP00000028466	PWWP domain-containing protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.442
ENSPLAP00000004039	ankrd11	ENSPLAP00000004039	ENSPLAP00000014814	PWWP domain-containing protein.	Ankyrin repeat domain 11.	0.488
ENSPLAP00000006015	ppib	ENSPLAP00000006015	ENSPLAP00000008350	TPR_REGION domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.415
ENSPLAP00000006928	ENSPLAP00000030099	ENSPLAP00000006928	ENSPLAP00000030099	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.488
ENSPLAP00000006928	LOC106937107	ENSPLAP00000006928	ENSPLAP00000009947	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.488
ENSPLAP00000006928	LOC106938905	ENSPLAP00000006928	ENSPLAP00000020825	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Protein tyrosine phosphatase non-receptor type 11b.	0.406
ENSPLAP00000006928	ptpn11	ENSPLAP00000006928	ENSPLAP00000030257	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.406
ENSPLAP00000006928	ptpn6	ENSPLAP00000006928	ENSPLAP00000002707	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	Protein tyrosine phosphatase non-receptor type 6.	0.406
ENSPLAP00000013169	ENSPLAP00000013662	ENSPLAP00000013169	ENSPLAP00000013662	Uncharacterized protein.	E1A binding protein p300 b.	0.749