27 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2). (499 aa)
	mef2d	MADS-box domain-containing protein. (173 aa)
	ENSPLAP00000030099	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
	LOC106962322	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	ext2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	LOC106941016	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (426 aa)
	LOC106949284	Sphingomyelin phosphodiesterase 3, neutral. (549 aa)
	LOC106940239	Ras-related protein Rap-1b. (184 aa)
	ENSPLAP00000020756	Uncharacterized protein. (289 aa)
	LOC106959966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
	tsku	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (348 aa)
	trip11	Thyroid hormone receptor interactor 11. (1953 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	LOC106954227	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	LOC106951603	Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (410 aa)
	LOC106937107	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	rap1a	RAP1A, member of RAS oncogene family b. (185 aa)
	anxa6	Annexin. (642 aa)
	MEF2D	MADS-box domain-containing protein. (496 aa)
	LOC106937739	Myocyte enhancer factor 2d. (499 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (778 aa)
	LOC106941801	Uncharacterized protein. (184 aa)
	LOC106952760	RAP1A, member of RAS oncogene family a. (185 aa)
	ENSPLAP00000004359	NGFI-A binding protein 2 (EGR1 binding protein 2). (460 aa)
	LOC106941263	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106940239	LOC106952760	ENSPLAP00000021580	ENSPLAP00000004370	Ras-related protein Rap-1b.	RAP1A, member of RAS oncogene family a.	0.895
LOC106940239	rap1a	ENSPLAP00000021580	ENSPLAP00000009594	Ras-related protein Rap-1b.	RAP1A, member of RAS oncogene family b.	0.895
LOC106941263	LOC106962322	ENSPLAP00000003997	ENSPLAP00000027647	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.954
LOC106941801	LOC106952760	ENSPLAP00000005264	ENSPLAP00000004370	Uncharacterized protein.	RAP1A, member of RAS oncogene family a.	0.895
LOC106941801	rap1a	ENSPLAP00000005264	ENSPLAP00000009594	Uncharacterized protein.	RAP1A, member of RAS oncogene family b.	0.895
LOC106952760	LOC106940239	ENSPLAP00000004370	ENSPLAP00000021580	RAP1A, member of RAS oncogene family a.	Ras-related protein Rap-1b.	0.895
LOC106952760	LOC106941801	ENSPLAP00000004370	ENSPLAP00000005264	RAP1A, member of RAS oncogene family a.	Uncharacterized protein.	0.895
LOC106952760	rap1a	ENSPLAP00000004370	ENSPLAP00000009594	RAP1A, member of RAS oncogene family a.	RAP1A, member of RAS oncogene family b.	0.923
LOC106954227	TGFBR2	ENSPLAP00000011505	ENSPLAP00000016741	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.905
LOC106959966	bmpr2	ENSPLAP00000019635	ENSPLAP00000027360	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.850
LOC106962322	LOC106941263	ENSPLAP00000027647	ENSPLAP00000003997	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.954
TGFBR2	LOC106954227	ENSPLAP00000016741	ENSPLAP00000011505	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.905
bmpr2	LOC106959966	ENSPLAP00000027360	ENSPLAP00000019635	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.850
ift80	trip11	ENSPLAP00000005778	ENSPLAP00000018423	Intraflagellar transport 80 homolog (Chlamydomonas).	Thyroid hormone receptor interactor 11.	0.474
rap1a	LOC106940239	ENSPLAP00000009594	ENSPLAP00000021580	RAP1A, member of RAS oncogene family b.	Ras-related protein Rap-1b.	0.895
rap1a	LOC106941801	ENSPLAP00000009594	ENSPLAP00000005264	RAP1A, member of RAS oncogene family b.	Uncharacterized protein.	0.895
rap1a	LOC106952760	ENSPLAP00000009594	ENSPLAP00000004370	RAP1A, member of RAS oncogene family b.	RAP1A, member of RAS oncogene family a.	0.923
trip11	ift80	ENSPLAP00000018423	ENSPLAP00000005778	Thyroid hormone receptor interactor 11.	Intraflagellar transport 80 homolog (Chlamydomonas).	0.474