76 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lef1	Lymphoid enhancer-binding factor 1. (364 aa)
	il10	Interleukin 10. (181 aa)
	socs3	Suppressor of cytokine signaling 3a. (201 aa)
	ilk	Integrin linked kinase. (452 aa)
	LOC106954227	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	spry1	Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (358 aa)
	ENSPLAP00000011906	Musculin (activated B-cell factor-1). (163 aa)
	LOC106964331	Uncharacterized protein. (188 aa)
	SOX10	SRY-box transcription factor 10. (476 aa)
	ENSPLAP00000013169	Uncharacterized protein. (99 aa)
	LOC106941608	Polycystic kidney disease 1a. (3231 aa)
	LOC106955479	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	LOC106951492	Serine peptidase inhibitor, Kunitz type, 2. (437 aa)
	LOC106954095	Low density lipoprotein receptor-related protein 6. (1608 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	LOC106955382	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (141 aa)
	srf	Serum response factor b. (601 aa)
	ENSPLAP00000016728	Inhibitor_I29 domain-containing protein. (145 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
	LOC106936785	Dystroglycan 1. (892 aa)
	LOC106936738	Nuclear factor of activated T cells 4. (841 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
	LOC106952668	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (515 aa)
	ENSPLAP00000018666	Transmembrane protein 59-like. (320 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	LOC106937460	Mothers against decapentaplegic homolog. (510 aa)
	sars1	Seryl-tRNA synthetase. (493 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (747 aa)
	LOC106947507	Transforming growth factor beta; Belongs to the TGF-beta family. (373 aa)
	greb1	Growth regulating estrogen receptor binding 1. (1789 aa)
	LOC106963210	NK3 homeobox 1. (183 aa)
	fem1b	Fem-1 homolog b (C. elegans). (656 aa)
	LOC106941242	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
	tcf21	Transcription factor 21. (175 aa)
	ENSPLAP00000022886	R-spondin 2. (227 aa)
	spint1	Serine peptidase inhibitor, Kunitz type 1 a. (481 aa)
	ENSPLAP00000023467	Uncharacterized protein. (462 aa)
	wt1	WT1 transcription factor b. (422 aa)
	LOC106949804	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (454 aa)
	ILK	Integrin linked kinase. (452 aa)
	AR	Androgen receptor. (757 aa)
	LOC106954882	Peptidase S72 domain-containing protein. (907 aa)
	LOC106965139	HMG box domain-containing protein. (450 aa)
	sox9	SRY-box transcription factor 9b. (482 aa)
	LOC106959588	Suppressor of cytokine signaling 3. (208 aa)
	ENSPLAP00000027758	Uncharacterized protein. (270 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (235 aa)
	ctsz	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	ENSPLAP00000027977	Laminin, alpha 1. (1501 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
	ppp3r1	Uncharacterized protein. (170 aa)
	LOC106946879	Endothelin 1. (183 aa)
	LOC106939913	FZ domain-containing protein. (289 aa)
	LOC106961533	Uncharacterized protein. (499 aa)
	LOC106939157	Bone morphogenetic protein 16. (477 aa)
	tmed2	Transmembrane p24 trafficking protein 2. (201 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	nrarp	NOTCH regulated ankyrin repeat protein a. (112 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2011 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	sox10	SRY-box transcription factor 10. (457 aa)
	timeless	Timeless circadian clock. (1176 aa)
	LOC106950541	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
	btbd7	BTB (POZ) domain containing 7. (407 aa)
	hhip	Hedgehog interacting protein. (697 aa)
	LOC106946506	Sprouty RTK signaling antagonist 2. (314 aa)
	LOC106963207	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
	LOC106944326	Mothers against decapentaplegic homolog. (503 aa)
	bmp2	Bone morphogenetic protein 2b. (409 aa)
	LOC106961202	MADS-box domain-containing protein. (471 aa)
	LOC106939331	Uncharacterized protein. (681 aa)
	LOC106940123	Uncharacterized protein. (255 aa)
	LOC106939239	Mothers against decapentaplegic homolog. (534 aa)
	LOC106950363	Gastrulation brain homeobox 2. (340 aa)
	LOC106961822	WT1 transcription factor a. (445 aa)
	LOC106940998	BTB (POZ) domain containing 7. (738 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ENSPLAP00000013169	ENSPLAP00000025137	ENSPLAP00000013169	Androgen receptor.	Uncharacterized protein.	0.711
AR	ENSPLAP00000018666	ENSPLAP00000025137	ENSPLAP00000018666	Androgen receptor.	Transmembrane protein 59-like.	0.431
AR	LOC106939331	ENSPLAP00000025137	ENSPLAP00000005224	Androgen receptor.	Uncharacterized protein.	0.924
AR	LOC106963210	ENSPLAP00000025137	ENSPLAP00000021280	Androgen receptor.	NK3 homeobox 1.	0.610
ENSPLAP00000011906	LOC106961822	ENSPLAP00000011906	ENSPLAP00000008192	Musculin (activated B-cell factor-1).	WT1 transcription factor a.	0.402
ENSPLAP00000011906	wt1	ENSPLAP00000011906	ENSPLAP00000023873	Musculin (activated B-cell factor-1).	WT1 transcription factor b.	0.402
ENSPLAP00000013169	AR	ENSPLAP00000013169	ENSPLAP00000025137	Uncharacterized protein.	Androgen receptor.	0.711
ENSPLAP00000013169	ENSPLAP00000018666	ENSPLAP00000013169	ENSPLAP00000018666	Uncharacterized protein.	Transmembrane protein 59-like.	0.455
ENSPLAP00000013169	LOC106939331	ENSPLAP00000013169	ENSPLAP00000005224	Uncharacterized protein.	Uncharacterized protein.	0.711
ENSPLAP00000013169	sars1	ENSPLAP00000013169	ENSPLAP00000020629	Uncharacterized protein.	Seryl-tRNA synthetase.	0.452
ENSPLAP00000016728	LOC106941242	ENSPLAP00000016728	ENSPLAP00000021891	Inhibitor_I29 domain-containing protein.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.641
ENSPLAP00000016728	LOC106963207	ENSPLAP00000016728	ENSPLAP00000003537	Inhibitor_I29 domain-containing protein.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.641
ENSPLAP00000016728	ctsh	ENSPLAP00000016728	ENSPLAP00000027840	Inhibitor_I29 domain-containing protein.	Cathepsin H; Belongs to the peptidase C1 family.	0.443
ENSPLAP00000016728	ctsz	ENSPLAP00000016728	ENSPLAP00000027870	Inhibitor_I29 domain-containing protein.	Cathepsin Z; Belongs to the peptidase C1 family.	0.641
ENSPLAP00000018666	AR	ENSPLAP00000018666	ENSPLAP00000025137	Transmembrane protein 59-like.	Androgen receptor.	0.431
ENSPLAP00000018666	ENSPLAP00000013169	ENSPLAP00000018666	ENSPLAP00000013169	Transmembrane protein 59-like.	Uncharacterized protein.	0.455
ENSPLAP00000018666	LOC106939331	ENSPLAP00000018666	ENSPLAP00000005224	Transmembrane protein 59-like.	Uncharacterized protein.	0.431
ENSPLAP00000023467	LOC106939913	ENSPLAP00000023467	ENSPLAP00000028818	Uncharacterized protein.	FZ domain-containing protein.	0.528
ENSPLAP00000023467	LOC106954095	ENSPLAP00000023467	ENSPLAP00000014136	Uncharacterized protein.	Low density lipoprotein receptor-related protein 6.	0.936
ENSPLAP00000023467	sfrp2	ENSPLAP00000023467	ENSPLAP00000031613	Uncharacterized protein.	Secreted frizzled-related protein 2.	0.528