(36 nodes) Response to interleukin-1 network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	zc3h12a	Zinc finger CCCH-type containing 12A. (627 aa)
	tank	TRAF family member-associated NFKB activator. (336 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (152 aa)
	YTHDC2	YTH domain containing 2. (1391 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (581 aa)
	LOC106937259	SCY domain-containing protein. (99 aa)
	LOC106937258	SCY domain-containing protein. (99 aa)
	ENSPLAP00000007639	Uncharacterized protein. (107 aa)
	rbmx	RNA binding motif protein X-linked. (383 aa)
	LOC106935033	Nuclear receptor subfamily 1, group d, member 1. (565 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (776 aa)
	LOC106947649	Nuclear receptor subfamily 1, group D, member 4a. (580 aa)
	LOC106936436	Zmp:0000000936. (460 aa)
	ENSPLAP00000010930	Uncharacterized protein. (296 aa)
	LOC106956350	Hyaluronidase. (440 aa)
	LOC106951552	Si:dkey-206d17.12. (404 aa)
	LOC106959505	Ribosomal protein S6 kinase. (803 aa)
	LOC106963449	Ribosomal protein S6 kinase. (783 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (857 aa)
	acod1	Aconitate decarboxylase 1. (487 aa)
	akap12	A kinase (PRKA) anchor protein 12b. (1358 aa)
	LOC106940496	Interleukin-1. (247 aa)
	LOC106948683	Chemokine (C-C motif) ligand 25b. (100 aa)
	LOC106963210	NK3 homeobox 1. (183 aa)
	LOC106936431	Uncharacterized protein. (471 aa)
	LOC106962807	CD40 molecule, TNF receptor superfamily member 5. (313 aa)
	ENSPLAP00000026092	C-C motif chemokine. (94 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (601 aa)
	LOC106940818	Immunoresponsive gene 1, like. (472 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1120 aa)
	ENSPLAP00000029465	Uncharacterized protein. (491 aa)
	LOC106947492	SCY domain-containing protein. (118 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (659 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000010930	LOC106936431	ENSPLAP00000010930	ENSPLAP00000025646	Uncharacterized protein.	Uncharacterized protein.	0.897
ENSPLAP00000010930	LOC106936436	ENSPLAP00000010930	ENSPLAP00000010017	Uncharacterized protein.	Zmp:0000000936.	0.897
ENSPLAP00000010930	LOC106940496	ENSPLAP00000010930	ENSPLAP00000018515	Uncharacterized protein.	Interleukin-1.	0.822
ENSPLAP00000010930	map2k7	ENSPLAP00000010930	ENSPLAP00000026257	Uncharacterized protein.	Mitogen-activated protein kinase kinase 7.	0.656
ENSPLAP00000010930	ripk2	ENSPLAP00000010930	ENSPLAP00000005915	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 2.	0.725
ENSPLAP00000010930	traf6	ENSPLAP00000010930	ENSPLAP00000026462	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
ENSPLAP00000026092	LOC106940496	ENSPLAP00000026092	ENSPLAP00000018515	C-C motif chemokine.	Interleukin-1.	0.660
ENSPLAP00000026092	LOC106947492	ENSPLAP00000026092	ENSPLAP00000029963	C-C motif chemokine.	SCY domain-containing protein.	0.426
ENSPLAP00000026092	LOC106948683	ENSPLAP00000026092	ENSPLAP00000018729	C-C motif chemokine.	Chemokine (C-C motif) ligand 25b.	0.538
ENSPLAP00000029465	acod1	ENSPLAP00000029465	ENSPLAP00000016187	Uncharacterized protein.	Aconitate decarboxylase 1.	0.899
LOC106936431	ENSPLAP00000010930	ENSPLAP00000025646	ENSPLAP00000010930	Uncharacterized protein.	Uncharacterized protein.	0.897
LOC106936431	LOC106936436	ENSPLAP00000025646	ENSPLAP00000010017	Uncharacterized protein.	Zmp:0000000936.	0.867
LOC106936431	LOC106940496	ENSPLAP00000025646	ENSPLAP00000018515	Uncharacterized protein.	Interleukin-1.	0.988
LOC106936431	traf6	ENSPLAP00000025646	ENSPLAP00000026462	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.909
LOC106936436	ENSPLAP00000010930	ENSPLAP00000010017	ENSPLAP00000010930	Zmp:0000000936.	Uncharacterized protein.	0.897
LOC106936436	LOC106936431	ENSPLAP00000010017	ENSPLAP00000025646	Zmp:0000000936.	Uncharacterized protein.	0.867
LOC106936436	LOC106940496	ENSPLAP00000010017	ENSPLAP00000018515	Zmp:0000000936.	Interleukin-1.	0.988
LOC106936436	traf6	ENSPLAP00000010017	ENSPLAP00000026462	Zmp:0000000936.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.909
LOC106937258	LOC106948683	ENSPLAP00000006696	ENSPLAP00000018729	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25b.	0.652
LOC106937259	LOC106948683	ENSPLAP00000006684	ENSPLAP00000018729	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25b.	0.652