(13 nodes) Disordered domain specific binding network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106945122	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
	LOC106955542	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (767 aa)
	ENSPLAP00000011849	Uncharacterized protein. (87 aa)
	cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
	LOC106948504	Fibronectin 1a. (2133 aa)
	dffb	DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (346 aa)
	LOC106935035	Alpha_adaptinC2 domain-containing protein. (574 aa)
	LOC106955541	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
	LOC106938556	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1575 aa)
	numa1	Uncharacterized protein. (2535 aa)
	LOC106942468	Heat shock protein 90, alpha (cytosolic), class B member 1. (723 aa)
	rb1	Retinoblastoma 1. (913 aa)
	fkbp8	Peptidylprolyl isomerase. (396 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000011849	LOC106935035	ENSPLAP00000011849	ENSPLAP00000024779	Uncharacterized protein.	Alpha_adaptinC2 domain-containing protein.	0.920
ENSPLAP00000011849	LOC106945122	ENSPLAP00000011849	ENSPLAP00000008242	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.896
ENSPLAP00000011849	cltc	ENSPLAP00000011849	ENSPLAP00000014271	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.896
LOC106935035	ENSPLAP00000011849	ENSPLAP00000024779	ENSPLAP00000011849	Alpha_adaptinC2 domain-containing protein.	Uncharacterized protein.	0.920
LOC106935035	LOC106938556	ENSPLAP00000024779	ENSPLAP00000026169	Alpha_adaptinC2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.947
LOC106935035	LOC106945122	ENSPLAP00000024779	ENSPLAP00000008242	Alpha_adaptinC2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.953
LOC106935035	cltc	ENSPLAP00000024779	ENSPLAP00000014271	Alpha_adaptinC2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.953
LOC106938556	LOC106935035	ENSPLAP00000026169	ENSPLAP00000024779	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Alpha_adaptinC2 domain-containing protein.	0.947
LOC106938556	LOC106945122	ENSPLAP00000026169	ENSPLAP00000008242	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.930
LOC106938556	cltc	ENSPLAP00000026169	ENSPLAP00000014271	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.930
LOC106942468	LOC106955541	ENSPLAP00000028679	ENSPLAP00000025290	Heat shock protein 90, alpha (cytosolic), class B member 1.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.908
LOC106942468	LOC106955542	ENSPLAP00000028679	ENSPLAP00000009399	Heat shock protein 90, alpha (cytosolic), class B member 1.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.923
LOC106942468	fkbp8	ENSPLAP00000028679	ENSPLAP00000031507	Heat shock protein 90, alpha (cytosolic), class B member 1.	Peptidylprolyl isomerase.	0.781
LOC106945122	ENSPLAP00000011849	ENSPLAP00000008242	ENSPLAP00000011849	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.896
LOC106945122	LOC106935035	ENSPLAP00000008242	ENSPLAP00000024779	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Alpha_adaptinC2 domain-containing protein.	0.953
LOC106945122	LOC106938556	ENSPLAP00000008242	ENSPLAP00000026169	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.930
LOC106945122	cltc	ENSPLAP00000008242	ENSPLAP00000014271	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.948
LOC106955541	LOC106942468	ENSPLAP00000025290	ENSPLAP00000028679	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.908
LOC106955541	LOC106955542	ENSPLAP00000025290	ENSPLAP00000009399	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.908
LOC106955541	fkbp8	ENSPLAP00000025290	ENSPLAP00000031507	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Peptidylprolyl isomerase.	0.781