60 items (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	REL	REL proto-oncogene, NF-kB subunit. (642 aa)
	nfkb1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (755 aa)
	LOC106938010	V-rel avian reticuloendotheliosis viral oncogene homolog A. (627 aa)
	LOC106944577	Uncharacterized protein. (530 aa)
	ENSPLAP00000002464	Myelin regulatory factor. (631 aa)
	tbx3	T-box transcription factor 3a. (703 aa)
	TBX2	T-box transcription factor 2. (686 aa)
	tp63	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (627 aa)
	LOC106954437	Signal transducer and activator of transcription. (801 aa)
	LOC106961120	Nuclear factor of activated T cells 2a. (614 aa)
	LOC106953622	T-box transcription factor Ta. (421 aa)
	ENSPLAP00000007593	DUF4801 domain-containing protein. (1799 aa)
	ENSPLAP00000008798	Uncharacterized protein. (170 aa)
	LOC106962496	Runt-related transcription factor. (411 aa)
	LOC106939021	Recombination signal binding protein for immunoglobulin kappa J region-like. (495 aa)
	LOC106945000	T-box transcription factor 16. (459 aa)
	stat4	Signal transducer and activator of transcription. (742 aa)
	TBX22	T-box transcription factor 22. (408 aa)
	LOC106951655	Signal transducer and activator of transcription. (754 aa)
	LOC106963750	Nuclear factor of activated T cells 1. (783 aa)
	rbpj	Recombination signal binding protein for immunoglobulin kappa J region. (468 aa)
	LOC106950871	Signal transducer and activator of transcription. (684 aa)
	nfatc3	Nuclear factor of activated T cells 3a. (1090 aa)
	stat3	Signal transducer and activator of transcription. (787 aa)
	LOC106963655	Signal transducer and activator of transcription. (787 aa)
	tp73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (710 aa)
	ENSPLAP00000013765	Uncharacterized protein. (196 aa)
	ENSPLAP00000015298	Signal transducer and activator of transcription 1a. (387 aa)
	LOC106959454	Uncharacterized protein. (346 aa)
	relb	V-rel avian reticuloendotheliosis viral oncogene homolog B. (575 aa)
	runx2	Runt-related transcription factor. (464 aa)
	LOC106952699	Recombination signal binding protein for immunoglobulin kappa J region a. (488 aa)
	tbx21	T-box transcription factor 21. (614 aa)
	LOC106936738	Nuclear factor of activated T cells 4. (841 aa)
	LOC106954620	Nuclear factor of activated T cells 2a. (882 aa)
	tbr1	T-box brain transcription factor 1b. (667 aa)
	nfkb2	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (887 aa)
	LOC106959978	Eomesodermin homolog a. (652 aa)
	LOC106959954	Runt domain-containing protein. (302 aa)
	tbxt	T-box transcription factor Tb. (436 aa)
	ENSPLAP00000020417	Uncharacterized protein. (367 aa)
	ENSPLAP00000020617	SH2 domain-containing protein. (231 aa)
	LOC106947933	Nuclear factor of activated T cells 5b. (1297 aa)
	LOC106944537	T-box transcription factor 5a. (517 aa)
	LOC106958307	T-box transcription factor 4. (549 aa)
	LOC106948392	Runt-related transcription factor. (406 aa)
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (342 aa)
	LOC106936637	Nuclear factor of activated T cells 5a. (1421 aa)
	LOC106940940	T-box transcription factor 18. (517 aa)
	LOC106936424	STAT_int domain-containing protein. (391 aa)
	tbx20	T-box transcription factor 20. (439 aa)
	ENSPLAP00000026775	RHD domain-containing protein. (462 aa)
	LOC106949059	T-box transcription factor 2a. (596 aa)
	eomes	Eomesodermin homolog b. (600 aa)
	tbx1	T-box transcription factor 1. (461 aa)
	tbx19	Uncharacterized protein. (407 aa)
	LOC106936953	RHD domain-containing protein. (505 aa)
	tbx15	T-box transcription factor 15. (614 aa)
	LOC106960253	RHD domain-containing protein. (880 aa)
	LOC106938275	RHD domain-containing protein. (940 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000007593	LOC106948392	ENSPLAP00000007593	ENSPLAP00000022267	DUF4801 domain-containing protein.	Runt-related transcription factor.	0.435
ENSPLAP00000007593	LOC106959954	ENSPLAP00000007593	ENSPLAP00000019641	DUF4801 domain-containing protein.	Runt domain-containing protein.	0.435
ENSPLAP00000007593	LOC106962496	ENSPLAP00000007593	ENSPLAP00000009113	DUF4801 domain-containing protein.	Runt-related transcription factor.	0.435
ENSPLAP00000007593	runx2	ENSPLAP00000007593	ENSPLAP00000016553	DUF4801 domain-containing protein.	Runt-related transcription factor.	0.435
ENSPLAP00000013765	LOC106948392	ENSPLAP00000013765	ENSPLAP00000022267	Uncharacterized protein.	Runt-related transcription factor.	0.435
ENSPLAP00000013765	LOC106952699	ENSPLAP00000013765	ENSPLAP00000016677	Uncharacterized protein.	Recombination signal binding protein for immunoglobulin kappa J region a.	0.405
ENSPLAP00000013765	LOC106953622	ENSPLAP00000013765	ENSPLAP00000006799	Uncharacterized protein.	T-box transcription factor Ta.	0.406
ENSPLAP00000013765	LOC106959954	ENSPLAP00000013765	ENSPLAP00000019641	Uncharacterized protein.	Runt domain-containing protein.	0.435
ENSPLAP00000013765	LOC106962496	ENSPLAP00000013765	ENSPLAP00000009113	Uncharacterized protein.	Runt-related transcription factor.	0.435
ENSPLAP00000013765	rbpj	ENSPLAP00000013765	ENSPLAP00000012067	Uncharacterized protein.	Recombination signal binding protein for immunoglobulin kappa J region.	0.405
ENSPLAP00000013765	runx2	ENSPLAP00000013765	ENSPLAP00000016553	Uncharacterized protein.	Runt-related transcription factor.	0.435
ENSPLAP00000015298	ENSPLAP00000020617	ENSPLAP00000015298	ENSPLAP00000020617	Signal transducer and activator of transcription 1a.	SH2 domain-containing protein.	0.571
ENSPLAP00000015298	LOC106936424	ENSPLAP00000015298	ENSPLAP00000025724	Signal transducer and activator of transcription 1a.	STAT_int domain-containing protein.	0.571
ENSPLAP00000015298	LOC106938010	ENSPLAP00000015298	ENSPLAP00000002173	Signal transducer and activator of transcription 1a.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.401
ENSPLAP00000015298	LOC106950871	ENSPLAP00000015298	ENSPLAP00000012839	Signal transducer and activator of transcription 1a.	Signal transducer and activator of transcription.	0.571
ENSPLAP00000015298	LOC106951655	ENSPLAP00000015298	ENSPLAP00000010471	Signal transducer and activator of transcription 1a.	Signal transducer and activator of transcription.	0.849
ENSPLAP00000015298	LOC106954437	ENSPLAP00000015298	ENSPLAP00000005967	Signal transducer and activator of transcription 1a.	Signal transducer and activator of transcription.	0.901
ENSPLAP00000015298	LOC106963655	ENSPLAP00000015298	ENSPLAP00000013288	Signal transducer and activator of transcription 1a.	Signal transducer and activator of transcription.	0.571
ENSPLAP00000015298	REL	ENSPLAP00000015298	ENSPLAP00000028761	Signal transducer and activator of transcription 1a.	REL proto-oncogene, NF-kB subunit.	0.401
ENSPLAP00000015298	relb	ENSPLAP00000015298	ENSPLAP00000015989	Signal transducer and activator of transcription 1a.	V-rel avian reticuloendotheliosis viral oncogene homolog B.	0.401